Dive into the world of lab testing and unlock the secrets to optimal health. In this episode, Joe sheds light on the crucial role lab tests play in understanding our health, cautioning against the limitations of standard tests often offered by conventional medicine.  Delve deep into the realm of comprehensive testing as Joe shares his insights on a variety of essential lab markers, including Complete Metabolic Panel, Complete Blood Count, Thyroid Panel, and Amino Acid Panel, among others.  Learn why these tests are vital for gaining a holistic view of your well-being. Discover common ..read more

We unravel the intricate relationship between sunlight, Vitamin D, and your genetic makeup, as we explore the pivotal role of Vitamin D in optimizing health and well-being. At the heart of this discussion lies the VDR gene, a genetic blueprint responsible for producing the Vitamin D receptor, as we uncover it’s role alongside Vitamin D in the body. We delve into the fascinating journey of Vitamin D synthesis, from sun-kissed skin to the activation of calcitriol, the biologically active form of Vitamin D.  Understanding your unique genetic profile empowers you to make informed decisions ab ..read more

Join Joe in a conversation with successful biohacker and CEO of Neurohacker Collective, James Schmachtenberger.  James shares his two-decade-long journey with biohacking, focusing on improved energy, cognitive function and how NAD changed his life. Learn about utilizing research, software solutions like genetics and lab tests, lifestyle changes, and supplementation for optimizing your health.  - Use code “SELFDECODE” to get 15% OFF any product at neurohacker.com - Check out SelfDecode: https://selfdecode.com/ - Join Joe’s online community: https://thejoecohenshow.com/  Timestamp ..read more

Unlock the secrets to longevity with our deep dive into biohacking, lab tests, and supplements! In this episode, we explore the crucial role of lab markers in longevity, optimal lab test ranges, and associations that impact aging. Dive into the world of supplements, addressing concerns about tolerance and when is the right time to supplement for lifespan. Joe and Michael discuss the Dunedin Pace Test and its significance in aging, while shedding light on the impact of lifestyle changes and immune system health. Going deeper into the science, Michael and Joe analyze mortality risk, liver damage ..read more

This episode explores the transformative potential of the UGT1A1 gene in your body’s ability to detox toxins. Uncover the role of this gene in Glucuronidation, a crucial chemical reaction that enhances the body's ability to detoxify. Learn about the impact of genetic variations which can reduce the activity of the UGT enzyme, hindering the body's detox capabilities. Discover practical solutions to counteract toxic buildup and support the body's natural detoxification processes. This episode unveils the science behind genetic detoxification, providing valuable insights into personalized approac ..read more

In this episode, Joe discusses the fascinating topic of methylation and its importance for overall health.  From explaining the tests that can determine if you're an over or under methylator, to providing recommendations on how to support your methylation process, Joe covers everything you need to know.  Discover how genetic variations, such as MTHFR and MTRR, can impact your need for nutrients like folate and B12.  Get insights into specific lab markers and supplements that can help optimize your methylation levels.  Find out how sleep, exercise, stress management, and det ..read more

Join us on an exhilarating journey into the intricate world of choline and the PEMT gene. Delve into the significance of choline and how it impacts cellular health, brain function, and beyond, and how PEMT plays a role in choline production. Discover the intricate genetic variants within PEMT, unravelling how certain alleles influence susceptibility to choline deficiency and associated risks. Plus, learn how estrogen stimulation plays a crucial role, posing unique challenges for different demographics. Tune in to 'SNPits' on The Joe Cohen Show to grasp the genetic intricacies impacting our hea ..read more

In this episode, Joe dives deep into the fascinating world of MTHFR and what you can do if you carry the negative variants! Join us as we unravel the mysteries surrounding these important topic and explore everything you need to know about genetic variations, folate metabolism, and the crucial role of methylation in our bodies.  Joe breaks down the science behind MTHFR, explains how to interpret your genetic results, and shares valuable insights on optimizing your folate levels.  Discover the benefits of methylfolate, explore the connection between homocysteine and methylation, and l ..read more

You’ve probably heard of the hype around MTHFR and how it affects methylation, but what about other genes implicated in the methylation process? In this SNPit the spotlight shifts to MTR and MTRR, and how they can affect levels of homocysteine in the body. Learn all about why homocysteine is important, how genetic variants can affect your levels, and other factors that affect methylation. … Because MTHFR doesn’t tell the whole story ..read more

In this episode of the Joe Cohen Show, we welcome Dr. Darshan Shah, a renowned health specialist, surgeon, author, and founder of Next Health. We dive deep into the cutting-edge health optimization methods used at his clinic to extend lifespan and health span. Dr. Shah shares intriguing insights on the role of biohacking, the importance of managing metabolic disease, micronutrient testing, and the function of certain nutrients in our bodies. Throughout the discussion, Joe demonstrates how he uses SelfDecode to analyze his personal health data, illuminating the power of personalized health mana ..read more