Driven in part by climate change, epidemics from mosquito-spread viruses are occurring with increasing frequency. Yet few among the American public are worried about getting West Nile or dengue virus in the coming months, and knowledge about how to protect oneself from these illnesses is spotty, a new survey finds ..read more

Scientists have uncovered how the parasite that causes malaria orchestrates their cell division -- which is key in enabling the parasite to transmit this deadly disease. They show how they have uncovered key regulators of how malaria parasites manage their cell division ..read more

A team has designed a new drug against malaria and identified its mechanism of action ..read more

Malaria is caused by a eukaryotic microbe of the Plasmodium genus, and is responsible for more deaths than all other parasitic diseases combined. In order to transmit from the human host to the mosquito vector, the parasite has to differentiate to its sexual stage, referred to as the gametocyte stage. Unlike primary sex determination in mammals, which occurs at the chromosome level, it is not known what causes this unicellular parasite to form males and females. New research has implemented high-resolution genomic tools to map the global repertoire of genes of gametocyte development towards th ..read more

While a mosquito bite is often no more than a temporary bother, in many parts of the world it can be scary. One mosquito species, Aedes aegypti, spreads the viruses that cause over 100,000,000 cases of dengue, yellow fever, Zika and other diseases every year. Another, Anopheles gambiae, spreads the parasite that causes malaria. The World Health Organization estimates that malaria alone causes more than 400,000 deaths every year. Indeed, their capacity to transmit disease has earned mosquitoes the title of deadliest animal ..read more

Circadian rhythms appear to influence vulnerability to malaria parasites ..read more

More than a quarter of Australians over the age of 50 take cholesterol-lowering drugs to prevent heart disease and strokes, but our bodies also need cholesterol to survive. Now, scientists say its role as a basic building block of life holds the key to treating deadly diseases caused by parasites, including malaria ..read more

Recent trials of an experimental malaria vaccine in healthy Malian adults found that all three tested regimens were safe. One of the trials enrolled 300 healthy women ages 18 to 38 years who anticipated becoming pregnant soon after immunization. That trial began with drug treatment to remove malaria parasites, followed by three injections spaced over a month of either saline placebo or the investigational vaccine at one of two dosages ..read more

Researchers have found a new way to identify genetic targets useful for control of mosquito populations, potentially offering an alternative to insecticides. Their study focused on the genetic basis of species incompatibility. They crossed Ae. aegypti, a major global arboviral disease vector, and its sibling species, Ae. mascarensis, from the Indian Ocean. When offspring is crossed back with one parent, about 10 percent of the progeny becomes intersex and is unable to reproduce ..read more

The insecticide-treated bed nets and insecticide sprays that were so effective in preventing mosquito bites -- and therefore malaria -- are increasingly viewed as the causes of household pest resurgence after pests became resistant to pesticides, according to a new article ..read more