Subcellular pathways through VGluT3-expressing mouse amacrine cells provide locally tuned object-motion-selective signals in the retina How the spatial distribution of synapses relates to the subcellular integration and transmission of signals is not fully understood. Here authors combine functional and connectomic analysis to map the subcellular flow of information in retinal amacrine cells ..read more

Parafoveal cone function in choroideremia assessed with adaptive optics optoretinography ..read more

Revealing speckle obscured living human retinal cells with artificial intelligence assisted adaptive optics optical coherence tomography Das and colleagues develop and evaluate a parallel discriminator generative adversarial network (P-GAN) for improved in-vivo imaging of retinal cellular structures. The P-GAN network improves retinal pigment epithelium contrast 3.5-fold and the overall throughput 99-fold ..read more

Phototoxicity of low doses of light and influence of the spectral composition on human RPE cells ..read more

Voluntary exercise preserves visual function and reduces inflammatory response in an adult mouse model of autosomal dominant retinitis pigmentosa ..read more

Abusive head trauma and the eye in infants and children - clinical guideline update by the royal college of ophthalmologists and the royal college of paediatrics and child health: executive summary ..read more

Papillary and peripapillary vascular densities and corresponding correlation with peripapillary retinal thicknesses using optical coherence tomography angiography in healthy children and adolescents ..read more

Intercellular communication atlas reveals Oprm1 as a neuroprotective factor for retinal ganglion cells How the neighboring cells contribute to the survival and functions of neuronal cells remains elusive. Here, authors identified the cell-cell interactions between retinal ganglion cells (RGCs) and other cells after RGC injury and discovered the μ-opioid receptor promotes RGC resilience ..read more

Dendritic mGluR2 and perisomatic Kv3 signaling regulate dendritic computation of mouse starburst amacrine cells How starburst amacrine cell (SAC) dendrites transform concentrically distributed synaptic inputs into branch-specific directional outputs is not fully understood. Here the authors report that dendritic mGluR2 signaling and somatic Kv3-mediated shunting coordinately implement SAC dendritic direction selectivity ..read more

Distributed feature representations of natural stimuli across parallel retinal pathways The precise organization of ON bipolar cells in the visual system remains poorly understood. Here, the authors discover that the mammalian ON bipolar pathway is divided into two streams that distribute the encoding of spatial and temporal information from naturalistic visual stimuli, respectively ..read more