MERCURIUS™ DRUG-seq is a rapid, cost-effective, RNA-extraction-free bulk 3’ mRNA-seq method. It provides ultra-high-throughput studies, such as drug discovery and toxicogenomic screens, with unbiased, transcriptome-wide gene expression data for hundreds of compounds or experimental conditions simultaneously. Featuring early sample barcoding technology, MERCURIUS™ DRUG-seq kits enable a single next-generation sequencing (NGS) lab technician to generate sequencing libraries from up to 5000-10’000 cells per well in 384 plates in less than two days without relying on any devoted automation. MERCU ..read more

Single-cell RNA sequencing (scRNA-seq) has created a new era of understanding cellular diversity by allowing gene expression analysis in individual cells, revealing details that are masked when studying bulk cell populations. This fine-tuned resolution is critical for unraveling cellular functions, states, and interactions, especially in complex tissues or disease environments ..read more

Revolutionizing Single-Cell RNA Sequencing with FLASH-seq  ..read more

Full-Length BRB-seq is a rapid, cost-effective, massively multiplexed bulk mRNA-seq library preparation method that harnesses poly(A) tailing, sample barcoding, and early sample pooling to provide users with robust transcriptome-wide data across the entire length of transcripts for up to 96 samples simultaneously. Our technology meets the demand for comprehensive ultra-high-throughput transcriptomic solutions that accelerate diverse pipelines, including drug discovery and development, toxicogenomics, biomarker discovery, agrogenomics, and basic research ..read more

As the field of genomics continues to expand, bulk RNA-seq has solidified its place as an essential technique for capturing a comprehensive snapshot of gene expression in a wide variety of biological samples. This method is particularly valuable for researchers who require a broad view of transcriptomic activity across entire tissues or cell populations, offering a balance between depth of insight and cost efficiency ..read more

Ultra-low input RNA-seq library preparation methods like our  MERCURIUS™ High Sensitivity BRB-seq kit provide researchers with powerful tools to explore the transcriptomes of small cell populations or precious clinical samples where extracted RNA quantities are minimal.  ..read more

A core goal of large-scale drug discovery screens is to use the transcriptomic effects of novel compounds on cells as indicators of both drug toxicity and potential mechanisms of action ..read more

Ion AmpliSeq™ from Thermo Fisher Scientific is a targeted PCR-based transcriptome profiling technology that allows users to measure the expression levels of over 20,000 genes, even in challenging low-quantity or degraded RNA samples such as from formalin-fixed paraffin-embedded (FFPE) tissue ..read more

MERCURIUS™ formalin-fixed paraffin-embedded sequencing (FFPE-seq) is a scalable and cost-effective full-length bulk RNA sequencing technology optimized for heavily degraded RNA samples with RNA integrity numbers (RIN) as low as 1 ..read more

QuantiGene™ Plex Gene Expression Assays from Invitrogen™ use hybridization-probe-based branched DNA technology to simultaneously quantify up to 80 known genes of interest per well of a 96- or 384-well plate ..read more