The Journal of Pharmacology and Experimental Therapeutics
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Aspet | Pharmacology & Experimental Therapeutics is a blog that is dedicated to promoting the field of pharmacology and therapeutics by publishing original research articles, reviews, and commentaries. Founded by the American Society for Pharmacology and Experimental Therapeutics in 1909, the blog provides insights into the development of new drugs, drug interactions, and the mechanism of..
The Journal of Pharmacology and Experimental Therapeutics
1d ago
Sensory-motor neuropathy in Mfn2 T105M knock-in mice and its reversal by a novel piperine-derived mitofusin activator ..read more
The Journal of Pharmacology and Experimental Therapeutics
1d ago
Nonclinical Profile of PF-06952229 (MDV6058), a Novel TGFβRI/Activin Like Kinase 5 (ALK-5) Inhibitor Supports Clinical Evaluation in Cancer ..read more
The Journal of Pharmacology and Experimental Therapeutics
1d ago
Evaluating the potential for psilocybin as a treatment for post-traumatic stress disorder ..read more
The Journal of Pharmacology and Experimental Therapeutics
1d ago
Factors influencing the Central Nervous System (CNS) distribution of the ATR inhibitor elimusertib (BAY1895344): Implications for the treatment of CNS tumors ..read more
The Journal of Pharmacology and Experimental Therapeutics
1d ago
Identification of pyrimidine structure-based compounds as allosteric ligands of the dopamine transporter as therapeutic agents for NeuroHIV ..read more
The Journal of Pharmacology and Experimental Therapeutics
1d ago
Alternative reinforcers enhance the effects of opioid antagonists, but not agonists, on oxycodone choice self-administration in nonhuman primates ..read more
The Journal of Pharmacology and Experimental Therapeutics
1M ago
Primaquine-5,6-orthoquinone is directly hemolytic to older G6PD deficient RBCs in a humanized mouse model ..read more
The Journal of Pharmacology and Experimental Therapeutics
1M ago
Effect of vascular senescence on the efficacy and safety of warfarin: insights from rat models and a prospective cohort study ..read more
The Journal of Pharmacology and Experimental Therapeutics
1M ago
Regulation of cannabinoid and opioid receptor levels by endogenous and pharmacological chaperones ..read more
The Journal of Pharmacology and Experimental Therapeutics
1M ago
Dysregulation of Human Hepatic Drug Transporters by Proinflammatory Cytokines ..read more