This blog is the first in a series exploring the critical role of safety pharmacology in drug discovery. In this post, we delve into the importance of human tissue studies in ensuring drug safety. Stay tuned for our next installment, where we will showcase real-world case studies highlighting our innovative approaches and successes in using human tissue models for safety assessment ..read more

Alzheimer's disease (AD) remains one of the most devastating neurodegenerative disorders, marked by progressive memory loss and cognitive decline. Central to this degeneration is the loss of neuronal connectivity, driven by the toxic accumulation of amyloid-β (Aβ) peptides in the brain. Despite extensive research, the precise mechanisms by which Aβ disrupts neural networks have remained elusive—until now ..read more

In the ever-evolving landscape of drug discovery, the ability to extract and analyze DNA and RNA from clinical biospecimens has become a cornerstone of innovative research. As we delve deeper into the molecular mechanisms of diseases, the quality of nucleic acid extraction plays a critical role in unlocking new therapeutic avenues. It is critical for downstream applications such as RT-PCR, RNA sequencing, and Next Generation Sequencing (NGS). The data obtained from these techniques can provide valuable insights that serve drug discovery and clinical research. At REPROCELL, we are leveraging h ..read more

In April 2015, the 106th annual meeting of the American Association for Cancer Research was held in Philadelphia, Pennsylvania. REPROCELL USA was in attendance and submitted a poster titled, Family History of Cancer in First-degree Relatives and Increased Cancer Risk: A Multinational Study ..read more

In recent years, artificial intelligence (AI) and machine learning have become integral to the field of pharmacology, revolutionizing how we approach drug discovery, diagnosis, and treatment pathways. As AI's influence grows, so does the necessity for transparency in its decision-making processes. This is where explainable AI comes into play, providing a crucial bridge between advanced computational models and human understanding.  ..read more

In the fast-paced world of biotechnology, quality and customization are crucial. Researchers constantly seek innovative ways to optimize their experiments and achieve specific outcomes. This is where custom oligosynthesis comes into play, offering tailored solutions that meet the unique requirements of various research projects ..read more

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Rapid advancements in biomedical research have underscored the need for new drug discovery tools that offer a transformative pathway to expedite the identification and development of novel therapeutic interventions. Mesenchymal Stem Cells (MSCs; also known as Mesenchymal Stromal Cells) provide researchers with a crucial tool they need to revolutionize therapeutic development ..read more

What are central laboratory services?  Central laboratory services encompass a range of crucial functions tailored to support complex, multi-site clinical trials. Contract research organizations (CROs) offering central laboratory services typically manage projects, prepare kits, and provide logistical support. They conduct laboratory assays and analyses required for sample testing, compile test results, and manage electronic data and document archiving. Additionally, they play a role in the collection, receipt, management, storage, and disposal of samples, ensuring seamless and efficient ..read more

The translation of preclinical findings to effective therapies requires overcoming a set of hurdles. These challenges are faced by all entities engaged in therapeutic drug discovery. Whether they follow the traditional pharmaceutical chemistry approach or use biotechnology to manufacture new molecules, they need to identify and test promising drug candidates, and to progress them though preclinical and clinical trials to prove that they can effectively and safely meet medical needs ..read more