Optimizing Human iPSC Aggregate And Organoid Production For Bioprinting
Drug Discovery Online
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3d ago
This study aimed to identify the optimal cell culture conditions to yield high cell density and maintain high cell viability with consistent aggregate morphology and pluripotency marker expression ..read more
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Evaluating Cell Culture Medium Performance In CAR-T Processes
Drug Discovery Online
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2w ago
This study examines the expansion, functionality, and phenotype of CAR-T cells cultured in the CellGenix® GMP T cell culture medium (TCM) compared to other commercially available T cell media ..read more
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Revolutionizing Viral Infectious Disease Research And Drug Discovery
Drug Discovery Online
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2w ago
Learn how Organ-Chips are being used to rapidly identify promising treatments, investigate virus evolution, and analyze how mechanical forces influence the innate immune response to viral infections ..read more
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Creating An Effective Pre-Clinical Model Of Bone Marrow
Drug Discovery Online
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2w ago
A Bone Marrow-Chip (BM-Chip) was created to recapitulate relevant hematopoietic cell types in a three-dimensional (3D), mechanically active next-generation ..read more
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A Better Immune Response To Vaccination: Using Lymphoid Follicle Organ-Chips
Drug Discovery Online
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2w ago
Discover a first-of-its-kind human LF-Chip containing B, T, plasma and antigen-presenting cells to test functional immunization responses to vaccines and adjuvants ..read more
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Proximal Tubule Kidney-Chip For Modeling Human Physiology
Drug Discovery Online
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3w ago
Discover how an Organ-Chip can be used to create a comprehensive recapitulation of the proximal tubule, addressing the need for more human-relevant preclinical models in the pharmaceutical industry ..read more
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Get Full Control Of Your T Cell Isolation
Drug Discovery Online
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3w ago
This study demonstrates the automated magnetic isolation of CD4/CD8+ cells from fresh or frozen leukapheresis using a functionally closed cell processing system paired with a modular application ..read more
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Sterilizing Grade Filter Performance With Biologic Drugs
Drug Discovery Online
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1M ago
Here, we analyze the throughput performance of sterilizing grade filters across moderate-to-high concentrations of mAbs and immunoglobulins and demonstrate how filter selection can impact your process ..read more
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Cytokine-Mediated Inflammation In A Relevant Preclinical Model
Drug Discovery Online
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1M ago
Learn about a novel preclinical model and how it enables the study of cytokine-mediated barrier inflammation mechanisms as well as the efficacy of anti-inflammatory therapeutics ..read more
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The Application Of The Species-Specific Liver-Chip In Predicting Hepatoxicity
Drug Discovery Online
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1M ago
An evaluation of 150 drug candidates causing adverse events in humans revealed testing in rats and dogs predicted only 71% of toxicities in humans. Discover a solution to this translational challenge ..read more
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