Predicting Human Liver Damage With A More Accurate In Vitro Hepatotoxicity Assay
Drug Discovery Online
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1w ago
This study explores whether a species-specific, multicellular, in vitro hepatotoxicity assays utilizing Liver-Chips can provide a greater understanding of hepatotoxicity mechanisms than animal models ..read more
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Investigating Key Mechanisms Of Parkinson’s With A Novel Model
Drug Discovery Online
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1w ago
Efforts to develop a dynamic “brain-on-a-chip” model that closely resembles the human substantia nigra could be applied to study mechanisms of Parkinson’s disease ..read more
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Studying Gut Inflammation And Barrier Disruption With Organ-On-A-Chip Technology
Drug Discovery Online
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1w ago
See how the Colon Intestine-Chip has been employed to model cytokine-mediated inflammation and barrier disruption in the intestine ..read more
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Evaluating CAR T-Cell Therapy Vascular Recruitment, Trafficking, And Killing
Drug Discovery Online
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1w ago
Learn about a more human-relevant platform that enables researchers to assess the trafficking and killing efficiency of immunotherapy as well as the proof-of-concept of immuno-oncology co-therapy ..read more
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Bulk Filling Of Drug Substance | Accurate Aliquoting
Drug Discovery Online
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1w ago
Bulk filling drug substances in traditional facilities is often a lengthy, manual process where operators are relied upon to adjust pump controls to achieve accurate filling. This method, spanning multiple shifts, increases process risk through errors that can compromise accuracy ..read more
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Expansion Of Specific Lymphocytes With A Xeno-Free, Serum-Free Medium
Drug Discovery Online
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1w ago
Explore the advantages of utilizing a xeno- and serum-free medium for the targeted expansion of cell subpopulations without the addition of serum ..read more
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Optimizing Human iPSC Aggregate And Organoid Production For Bioprinting
Drug Discovery Online
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2w ago
This study aimed to identify the optimal cell culture conditions to yield high cell density and maintain high cell viability with consistent aggregate morphology and pluripotency marker expression ..read more
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Evaluating Cell Culture Medium Performance In CAR-T Processes
Drug Discovery Online
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1M ago
This study examines the expansion, functionality, and phenotype of CAR-T cells cultured in the CellGenix® GMP T cell culture medium (TCM) compared to other commercially available T cell media ..read more
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Revolutionizing Viral Infectious Disease Research And Drug Discovery
Drug Discovery Online
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1M ago
Learn how Organ-Chips are being used to rapidly identify promising treatments, investigate virus evolution, and analyze how mechanical forces influence the innate immune response to viral infections ..read more
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Creating An Effective Pre-Clinical Model Of Bone Marrow
Drug Discovery Online
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1M ago
A Bone Marrow-Chip (BM-Chip) was created to recapitulate relevant hematopoietic cell types in a three-dimensional (3D), mechanically active next-generation ..read more
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