Protective effects of Notoginsenoside R2 on reducing lipid accumulation and mitochondrial dysfunction in diabetic nephropathy through regulation of c-Src
BioMed Central » Chinese Medicine
by Xieyi Guo, Liu Yang, Xiaoning An, Maofang Hu, Yilan Shen, Niansong Wang, Youhua Xu and Dingkun Gui
4d ago
The treatment options to delay the progression of diabetic nephropathy (DN), a key contributor to chronic kidney disease (CKD), are urgently needed. Previous studies reported that traditional Chinese medicine ..read more
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Tangeretin alleviates sepsis-induced acute lung injury by inhibiting ferroptosis of macrophage via Nrf2 signaling pathway
BioMed Central » Chinese Medicine
by Hui Zhang, Yan Wang, Shenghua Wang, Xiaomei Xue, Kai Huang, Dunfeng Xu, Lai Jiang, Siyuan Li and Yunqian Zhang
4d ago
Sepsis-induced acute lung injury (ALI) is a severe clinical condition accompanied with high mortality. Tangeretin, which is widely found in citrus fruits, has been reported to exert antioxidant and anti-inflam ..read more
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Electroacupuncture alleviates paclitaxel-induced peripheral neuropathy by reducing CCL2-mediated macrophage infiltration in sensory ganglia and sciatic nerve
BioMed Central » Chinese Medicine
by Yuanyuan Li, Ruoyao Xu, Muyan Chen, Kaige Zheng, Huimin Nie, Chengyu Yin, Boyu Liu, Yan Tai, Junying Du, Jie Wang, Jianqiao Fang and Boyi Liu
4d ago
Paclitaxel-induced peripheral neuropathy (PIPN) is prevalent among patients receiving paclitaxel chemotherapy, which results in sensory abnormality as well as neuropathic pain. Conventional medications lack ef ..read more
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Network pharmacology: a crucial approach in traditional Chinese medicine research
BioMed Central » Chinese Medicine
by Yiyan Zhai, Liu Liu, Fanqin Zhang, Xiaodong Chen, Haojia Wang, Jiying Zhou, Keyan Chai, Jiangying Liu, Huiling Lei, Peiying Lu, Meiling Guo, Jincheng Guo and Jiarui Wu
1w ago
Network pharmacology plays a pivotal role in systems biology, bridging the gap between traditional Chinese medicine (TCM) theory and contemporary pharmacological research. Network pharmacology enables research ..read more
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Construction of machine learning-based models for screening the high-risk patients with gastric precancerous lesions
BioMed Central » Chinese Medicine
by Shuxian Yu, Haiyang Jiang, Jing Xia, Jie Gu, Mengting Chen, Yan Wang, Xiaohong Zhao, Zehua Liao, Puhua Zeng, Tian Xie and Xinbing Sui
1w ago
The individualized prediction and discrimination of precancerous lesions of gastric cancer (PLGC) is critical for the early prevention of gastric cancer (GC). However, accurate non-invasive methods for disting ..read more
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Two-dimensional cell membrane chromatography guided screening of myocardial protective compounds from Yindan Xinnaotong soft capsule
BioMed Central » Chinese Medicine
by Si-Min Shao, Xuan Ji, Xing Wang, Run-Zhou Liu, Yu-Ru Cai, Xiaobing Lin, Ze-Jie Zeng, Ling Chen, Liu Yang, Hua Yang and Wen Gao
1w ago
Cell membrane chromatography (CMC) is a biochromatography with a dual function of recognition and separation, offering a distinct advantage in screening bioactive compounds from Chinese medicines (CMs). Yindan ..read more
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Electroacupuncture attenuates ferroptosis by promoting Nrf2 nuclear translocation and activating Nrf2/SLC7A11/GPX4 pathway in ischemic stroke
BioMed Central » Chinese Medicine
by Xi-chen Yang, Ya-ju Jin, Rong Ning, Qiu-yue Mao, Peng-yue Zhang, Li Zhou, Cheng-cai Zhang, Yi-chen Peng and Na Chen
1w ago
Electroacupuncture has been shown to play a neuroprotective role following ischemic stroke, but the underlying mechanism remains poorly understood. Ferroptosis has been shown to play a key role in the injury p ..read more
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Jianwei Xiaoshi oral liquid attenuates high-calorie diet-induced dyspepsia in immature rats via regulating the pancreatic secretion pathway and maintaining the homeostasis of intestinal microbiota
BioMed Central » Chinese Medicine
by Yan Zhang, Xiaolu Wei, Shan Jiang, Wenya Gao, Kun Wang, Hongjie Wang, Huijun Wang, Nan Si, Yanyan Zhou, Keke Luo, Mengxiao Wang, Yuyang Liu, Lihua Chen, Liqi Ni and Haiyu Zhao
1w ago
Jianwei Xiaoshi oral liquid (JWXS), a classical traditional prescription comprising various edible medicinal plants, has demonstrated significant efficacy in treating paediatric indigestion. It originates from ..read more
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Wu-Mei-Wan enhances brown adipose tissue function and white adipose browning in obese mice via upregulation of HSF1
BioMed Central » Chinese Medicine
by Shen Chen, Kexin Nie, Hongzhan Wang, Yang Gao, Xinyue Jiang, Hao Su, Zhi Wang, Yueheng Tang, Fuer Lu, Hui Dong and Jingbin Li
1w ago
This research aims to explore the anti-obesity potential of Wu-Mei-Wan (WMW), particularly its effects on adipose tissue regulation in obese mice induced by a high-fat diet (HFD). The study focuses on understa ..read more
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Magnolia kobus DC. suppresses neointimal hyperplasia by regulating ferroptosis and VSMC phenotypic switching in a carotid artery ligation mouse model
BioMed Central » Chinese Medicine
by Jong Min Kim, Yiseul Kim, Hyun-Jin Na, Haeng Jeon Hur, Sang Hee Lee and Sung
1w ago
Magnolia kobus DC (MO), as a plant medicine, has been reported to have various physiological activities, including neuroprotective, anti-inflammatory, and anti-diabetic effects. However, vascular protective effec ..read more
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