Satellite cells in ageing: use it or lose it
The Royal Society » Open Biology
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1y ago
Individuals that maintain healthy skeletal tissue tend to live healthier, happier lives as proper muscle function enables maintenance of independence and actuation of autonomy. The onset of skeletal muscle decline begins around the age of 30, and muscle ..read more
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A new perspective for mitigation of SARS-CoV-2 infection: priming the innate immune system for viral attack
The Royal Society » Open Biology
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1y ago
The course of infection by SARS-CoV-2 frequently includes a long asymptomatic period, followed in some individuals by an immune dysregulation period that may lead to complications and immunopathology-induced death. This course of disease suggests that the ..read more
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Age separation dramatically reduces COVID-19 mortality rate in a computational model of a large population
The Royal Society » Open Biology
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1y ago
COVID-19 pandemic has caused a global lockdown in many countries throughout the world. Faced with a new reality, and until a vaccine or efficient treatment is found, humanity must figure out ways to keep the economy going, on one hand, while keeping the ..read more
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A practical view of fine-mapping and gene prioritization in the post-genome-wide association era
The Royal Society » Open Biology
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1y ago
Over the past 15 years, genome-wide association studies (GWASs) have enabled the systematic identification of genetic loci associated with traits and diseases. However, due to resolution issues and methodological limitations, the true causal variants and ..read more
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