Thyroid Feedback Quantile-based Index and cardiovascular diseases. Abstract Background Previous study has demonstrated a link between TFQI, indicating the central sensitivity of thyroid hormones, and conditions like obesity, diabetes, and metabolic syndrome. Hypothesis Nevertheless, the potential relationship between TFQI and cardiovascular disease (CVD) in individuals with normal thyroid function has yet to be established. Methods The present research is a retrospective cohort investigation that included a total of 6297 individuals who had normal function of the thyroid and no history of th ..read more

Abstract Background Rate control is the most commonly employed first-line management strategy for atrial fibrillation (AF) in patients with chronic kidney disease (CKD). Principal agents used to control heart rate (HR) include beta-blockers (BB) and nondihydropyridine calcium channel blockers (ND-CCB). However, there is a paucity of published studies of the differences between those drugs in CKD patients. Hypothesis The present study aimed to investigate the differences, in terms of hospitalizations due to a poor HR control, in patients with AF under a rate-control strategy according to glomer ..read more

we performed a meta-analysis to establish the overall incidence of chemotherapy-related cardiac dysfunction in cancer patients. The overall pooled incidence of chemotherapy-related cardiac dysfunction in cancer patients was 63.21 per 1000 person-years (95% CI: 57.28−69.14). Abstract Background Cancer patients are increasingly affected by chemotherapy-related cardiac dysfunction. The reported incidence of this condition vary significantly across different studies. Hypothesis A better comprehensive understanding of chemotherapy-related cardiac dysfunction incidence in cancer patients is impera ..read more

The results of this study showed a negative correlation between life's essential 8 (LE8) and high-sensitivity C-reactive protein (hs-CRP), and a stronger association between health factors and hs-CRP than health behaviors. Abstract Background Earlier studies showed a negative correlation between life's simple 7 (LS7) and high-sensitivity C-reactive protein (hs-CRP), but no association has been found between life's essential 8 (LE8), an improved version of LS7, and hs-CRP. Hypothesis This study investigated the association between LE8 and hs-CRP utilizing data from the National Health and Nut ..read more

Advanced HF patients with a higher QRS duration (QRSd)/LV end-diastolic volume (LVEDV) ratio showed better survival in this small-body–size population. Thus, the QRSd/LVEDV might serve as a relatively simple index to improve patient selection for cardiac resynchronization therapy in patients with mid-wide QRSd. Abstract Background We analyzed the influence of the QRS duration (QRSd) to LV end-diastolic volume (LVEDV) ratio on cardiac resynchronization therapy (CRT) outcomes in heart failure patients classified as III/IV per the New York Heart Association (NYHA) and with small body size. Hypo ..read more

This study compared an artificial intelligence (AI) (convolutional neural network [CNN])-based 2 hours single-lead Holter and a traditional 24 hours Holter for premature supraventricular contraction (PSVC)/premature ventricular contraction (PVC) detection. The two methods showed good diagnostic consistency. In conclusion, the AI-based 2 hours single-lead Holter improved the PSVC/PVC detection efficiency, shortened the wearing period, and provided new insights for future arrhythmia diagnosis. Abstract Background Electrocardiography (ECG) and 24 hours Holter monitoring (24 h-Holter) provided v ..read more

For the first time ever, our study utilized artificial intelligence to build the prediction model for vascular calcification (VC) risk in Chinese type 2 diabetics aged 27–92. The 10 important characteristics that affect VC were identified and ranked. Serum uric acid, a newly discovered possible factor influencing VC, has attracted our attention. Abstract Background Recently, patients with type 2 diabetes mellitus (T2DM) have experienced a higher incidence and severer degree of vascular calcification (VC), which leads to an increase in the incidence and mortality of vascular complications in ..read more

Key findings: A simple and effective indicator of high mortality risk in AMI patients is needed. The relationship between BPV and AMI is poorly understood and controversial. We show that DBP-ARV is significantly associated with short- and long-term mortality. SBP-ARV is not significantly associated with mortality risk in patients with AMI. Abstract Background In recent years, the mortality of patients with AMI has not declined significantly. The relationship between blood pressure variability (BPV) and acute myocardial infarction (AMI) is unclear. We explored the relationship between 24-h BP ..read more

Based on a cohort of 13 682 patients with acute coronary syndrome (ACS) who underwent percutaneous coronary intervention (PCI), prediabetes was not associated with a higher rate of adverse events; however, diabetes significantly increased the rates of major adverse cardiac and cerebrovascular events (MACCE) and all-cause mortality. Abstract Background Unlike diabetes, the effect of prediabetes on outcomes in patients with acute coronary syndrome (ACS) who underwent percutaneous coronary intervention (PCI) is not much investigated. We investigated the association between fasting glycemic stat ..read more

Abstract Background The association between Interdialytic home blood pressure variability (BPV) and the prognosis of patients undergoing maintenance hemodialysis (MHD) largely unknown. Hypothesis We proposed the hypothesis that interdialytic home BPV exert effect on cardiac and all-cause mortality among individuals undergoing MHD. Methods A total of 158 patients receiving MHD at the hemodialysis unit of Wuhan Fourth Hospital between December 2019 and August 2020 were included in this prospective cohort study. Patients were divided into tertiles according to the systolic BPV (SBPV), and the pr ..read more