Correction: Comparative analysis of the interactions of different Streptococcus suis strains with monocytes, granulocytes and the complement system in porcine blood
Veterinary Research
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1w ago
Epithelial damage due to gastrointestinal disorders frequently causes severe disease in horses. To study the underlying pathophysiological processes, we aimed to establish equine jejunum and colon enteroids (e ..read more
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A matter of differentiation: equine enteroids as a model for the in vivo intestinal epithelium
Veterinary Research
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1w ago
Epithelial damage due to gastrointestinal disorders frequently causes severe disease in horses. To study the underlying pathophysiological processes, we aimed to establish equine jejunum and colon enteroids (e ..read more
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Pasteurella multocida activates Rassf1-Hippo-Yap pathway to induce pulmonary epithelial apoptosis
Veterinary Research
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1w ago
is an opportunistic zoonotic pathogen that primarily causes fatal respiratory diseases, such as pneumonia and respiratory syndromes. However, the precise mechanistic understanding of how ..read more
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An equine iPSC-based phenotypic screening platform identifies pro- and anti-viral molecules against West Nile virus
Veterinary Research
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1w ago
Outbreaks of West Nile virus (WNV) occur periodically, affecting both human and equine populations. There are no vaccines for humans, and those commercialised for horses do not have sufficient coverage. Specif ..read more
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Construction of recombinant fluorescent LSDV for high-throughput screening of antiviral drugs
Veterinary Research
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1w ago
Lumpy skin disease virus (LSDV) infection is a major socio-economic issue that seriously threatens the global cattle-farming industry. Here, a recombinant virus LSDV-ΔTK/EGFP, expressing enhanced green fluores ..read more
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Equine enteroid-derived monolayers recapitulate key features of parasitic intestinal nematode infection
Veterinary Research
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3w ago
Stem cell-derived organoid cultures have emerged as attractive experimental models for infection biology research regarding various types of gastro-intestinal pathogens and host species. However, the large siz ..read more
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Molecular mechanism of bovine Gasdermin D-mediated pyroptosis
Veterinary Research
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3w ago
Pyroptosis is a form of programmed cell death characterized by cell swelling, pore formation in the plasma membrane, lysis, and releases of cytoplasmic contents. To date, the molecular mechanism of human and m ..read more
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Non-cytopathic bovine viral diarrhea virus (BVDV) inhibits innate immune responses via induction of mitophagy
Veterinary Research
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3w ago
Bovine viral diarrhea virus (BVDV) belongs to the genus . Mitophagy plays important roles in virus-host interactions. Here, we provide evidence that non-cytopathic (NCP) B ..read more
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A chimeric porcine reproductive and respiratory syndrome virus 1 strain containing synthetic ORF2-6 genes can trigger T follicular helper cell and heterologous neutralizing antibody responses and confer enhanced cross-protection
Veterinary Research
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3w ago
The prevalence of porcine reproductive and respiratory syndrome virus 1 (PRRSV1) isolates has continued to increase in Chinese swine herds in recent years. However, no effective control strategy is available f ..read more
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Characterizing the detection of inactivated Mycoplasma hyopneumoniae DNA in the respiratory tract of pigs
Veterinary Research
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1M ago
PCR result in a clinical specimen may eventually represent the mere detection of non-viable bacteria, complicating the diagnostic interpretation. Thus, the objective of this st ..read more
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