Spatial biology, cell therapy, targeted protein degradation, omics, and large-scale computational analyses of all types dominated at this year’s American Association of Cancer Research (AACR) Annual Meeting in San Diego, California. Among the over 7,200 abstracts, 3,000 posters, and dozens of symposia presented—the largest in the event’s history—show attendees got a glimpse of the future of what’s to come for cancer care ..read more

Previously considered distinct disciplines, the fields of immunology and metabolism are converging in a groundbreaking realization that metabolic processes intricately regulate immune cell function. Known as immunometabolism, the field explores the intricate interplay between metabolism and immune function and helps unravel the complex web of interactions that shape how our body responds to pathogens, diseases, and therapies. Current studies seek to understand how metabolic processes influence the behavior of immune cells such as their development, activation, and function, ultimately hoping ..read more

Peer review is the independent assessment of a manuscript by experts in related academic fields. It is designed to evaluate the quality, validity, and originality of papers for publication in scholarly journals. The ultimate purpose of a peer review is to preserve the integrity of science, and it’s one of the fairest methods of evaluating the quality of research.1 Despite its critical importance, early-career researchers often have limited resources for learning about peer review.2 If you’re getting ready to submit a paper or have one currently going through review, this post can help familia ..read more

We’re proud to partner with The Michael J. Fox Foundation for Parkinson’s Research (MJFF) to move Parkinson's disease (PD) research forward. Learn more about the partnership and explore PD resources. —  ..read more

At Cell Signaling Technology (CST), our philosophy of giving and supporting those in need is at the heart of everything we do. Our annual Global Giving program represents a portion of our total giving for each year, and is one of many ways we help the impoverished and underserved in our global communities ..read more

The need for antibody conjugation is on the rise due to the increased use of multiplexing. Not only are existing platforms such as traditional and spectral flow cytometry seeing panel sizes grow, but the development of advanced technologies for spatial biology has meant that more targets are being simultaneously detected with novel immunofluorescent (IF) and immunohistochemistry (IHC) methods. Yet, while antibodies labeled with fluorophores, enzymes, metal ions, or oligonucleotides are in high demand, they may not always be available commercially ..read more

Networking is an important part of any research career,1 with many experts considering networking and networking-focused training an essential part of the PhD and postdoctoral experience. Such experience is an invaluable asset to any individual, significantly enhancing their personal profile when searching for job opportunities or when it comes to establishing new working relationships ..read more

We’re thrilled to announce the winners of the 4th annual Rising Black Scientists Awards essay competition! We were captivated from the onset after receiving the submissions and reading the inspiring stories of the researchers behind them. Read on to learn more about the Rising Black Scientists Awards and find links to the winning essays ..read more

Chromatin profiling with methods like ChIP-Seq, CUT&RUN, and now CUT&Tag have significantly contributed to our understanding of disease mechanisms and how modulating epigenetic changes can be used to develop novel therapeutics. After DNA libraries are generated using one of these three techniques, the libraries can be quantitated using platforms like the NanoDrop or Qubit system, QC’d with instruments like the Bioanalyzer or TapeStation system, and analyzed with next-generation sequencing (NGS). But what happens if the CUT&Tag DNA library concentration or the signal generated by ..read more

Networking and self-promotion are essential parts of any scientist's career, and while many might find them daunting, there are tricks and skills you can learn to help make the networking process a little easier.1 One of the most important parts of networking is the so-called ‘elevator pitch’–a short summary of your research project or skills that is easy for a general scientific audience to understand.  This post will share tips on how to craft an effective elevator pitch and adapt it for networking in an increasingly online world ..read more