Autologous stem cell transplant shows promise for young patients with severe juvenile systemic sclerosis
News Medical Life Sciences » Scleroderma
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3w ago
New research at ACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeting, shows that patients with refractory juvenile systemic sclerosis improved significantly on nearly all measures for two years following autologous stem cell transplant ..read more
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Genetic causes of Raynaud’s phenomenon identified
News Medical Life Sciences » Scleroderma
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1M ago
Researchers at Queen Mary University of London’s Precision Healthcare Research Institute (PHURI) and the Berlin Institute of Health (BIH) at Charité – Universitätsmedizin Berlin have identified the genetic causes of Raynaud’s phenomenon. Their findings, published today (12 October) in Nature Communications, could lead to the first effective treatments for people with Raynaud’s ..read more
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Extracellular vesicles may drive fibrosis in scleroderma
News Medical Life Sciences » Scleroderma
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4M ago
Extracellular vesicles, responsible for cell-to-cell communication, might be a driver of fibrosis in systemic sclerosis, according to a recent paper in Arthritis and Rheumatology ..read more
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Study finds improved survival in patients with SLE-associated PAH
News Medical Life Sciences » Scleroderma
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6M ago
A team from Peking Union Medical College Hospital in Beijing, China, have explored changes in the characteristics, treatment, and 5-year survival for SLE-associated PAH in the last decade, and possible reasons for survival change ..read more
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A critical subset of fibroblasts may lie at the origins of rare autoimmune disease
Scleroderma News, Articles and Research
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11M ago
Supporting actors sometimes steal the show. In a new study published today in Cell, researchers headed by Prof. Ido Amit at the Weizmann Institute of Science have shown that supporting cells called fibroblasts, long viewed as uniform background players, are in fact extremely varied and vital ..read more
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Biodegradable nanoparticle used in medical sutures could help combat scleroderma
Scleroderma News, Articles and Research
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11M ago
Investigators have discovered that a biodegradable nanoparticle used in medical sutures could combat a rare, sometimes-fatal autoimmune disease ..read more
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Elevated and sustained autoantibodies following COVID-19
News Medical Life Sciences » Scleroderma
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11M ago
A new study demonstrated that autoantibody levels rise following acute SARS-CoV-2 infection and remain to be elevated for about six months ..read more
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Urgent action needed to address disparities in women’s heart health
News Medical Life Sciences » Scleroderma
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11M ago
Investing in and improving research, awareness and equity in women's heart health are critical for the health and well-being of women, according to a new Presidential Advisory from the American Heart Association, published today in the Association's flagship journal Circulation ..read more
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Chemokine-DNA nanoparticles can induce chronic, dysfunctional immune responses
News Medical Life Sciences » Scleroderma
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11M ago
Small proteins, called chemokines, that direct immune cells toward sites of infection can also form DNA-bound nanoparticles that can induce chronic, dysfunctional immune responses, according to a new study by researchers at Weill Cornell Medicine and Hospital for Special Surgery (HSS ..read more
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Study identifies mechanism behind 'cytokine storm' in COVID-19 patient lungs
News Medical Life Sciences » Scleroderma
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11M ago
A new study by HSS Research Institute scientists identifies a mechanism by which SARS-CoV-2 induces the inflammatory response in COVID-19 patient lungs, so-called "cytokine storm", that can lead to lasting tissue damage and poor patient outcomes ..read more
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