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Alzheimer's Research & Therapy

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Alzheimer's Research & Therapy is the major forum for translational research into Alzheimer's disease. An international peer-reviewed journal, it publishes open access basic research with a translational focus, as well as clinical trials, research into drug discovery and development, and epidemiologic studies.

Associations of plasma neurofilament light chain with cognition and neuroimaging measures in community-dwelling early old age men

Alzheimer's Research & Therapy

3d ago

Rongxiang Tang, Erik Buchholz, Anders M. Dale, Robert A. Rissman, Christine Fennema-Notestine, Nathan A. Gillespie, Donald J Hagler Jr, Michael J. Lyons, Michael C. Neale, Matthew S. Panizzon, Olivia K. Puckett, Chandra A. Reynolds, Carol E. Franz, William S. Kremen and Jeremy A. Elman ..read more

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Association of midlife body-weight variability and cycles with earlier dementia onset: a nationwide cohort study

Alzheimer's Research & Therapy

3d ago

Yujin Park, Su Hwan Kim, Jiwon Ryu and Hyung-Jin Yoon ..read more

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Utilization of fluid-based biomarkers as endpoints in disease-modifying clinical trials for Alzheimer’s disease: a systematic review

Alzheimer's Research & Therapy

3d ago

Marlies Oosthoek, Lisa Vermunt, Arno de Wilde, Bram Bongers, Daniel Antwi-Berko, Philip Scheltens, Pieter van Bokhoven, Everard G. B. Vijverberg and Charlotte E. Teunissen ..read more

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Alzheimer’s and neurodegenerative disease biomarkers in blood predict brain atrophy and cognitive decline

Alzheimer's Research & Therapy

3d ago

Heather E. Dark, Yang An, Michael R. Duggan, Cassandra Joynes, Christos Davatzikos, Guray Erus, Alexandria Lewis, Abhay R. Moghekar, Susan M. Resnick and Keenan A. Walker ..read more

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N, N-Dimethyltryptamine, a natural hallucinogen, ameliorates Alzheimer’s disease by restoring neuronal Sigma-1 receptor-mediated endoplasmic reticulum-mitochondria crosstalk

Alzheimer's Research & Therapy

3d ago

Dan Cheng, Zhuo-Gui Lei, Kin Chu, Oi Jin Honey Lam, Chun Yuan Chiang and Zhang-Jin Zhang ..read more

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Risk of conversion to mild cognitive impairment or dementia among subjects with amyloid and tau pathology: a systematic review and meta-analysis

Alzheimer's Research & Therapy

2w ago

Zsolt Huszár, Marie Anne Engh, Márk Pavlekovics, Tomoya Sato, Yalea Steenkamp, Bernard Hanseeuw, Tamás Terebessy, Zsolt Molnár, Péter Hegyi and Gábor Csukly ..read more

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Synaptic vesicle glycoprotein 2 A in serum is an ideal biomarker for early diagnosis of Alzheimer’s disease

Alzheimer's Research & Therapy

2w ago

Xiaoling Wang, Xiaomin Zhang, Jing Liu, Jingjing Zhang, Congcong Liu, Yuting Cui, Qiao Song, Yuli Hou, Yaqi Wang, Qian Zhang, Yingzhen Zhang, Yujian Fan, Jianping Jia and Peichang Wang ..read more

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Prefrontal intra-individual ERP variability and its asymmetry: exploring its biomarker potential in mild cognitive impairment

Alzheimer's Research & Therapy

2w ago

Joel Eyamu, Wuon-Shik Kim, Kahye Kim, Kun Ho Lee and Jaeuk U. Kim ..read more

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Pathophysiology characterization of Alzheimer’s disease in South China’s aging population: for the Greater-Bay-Area Healthy Aging Brain Study (GHABS)

Alzheimer's Research & Therapy

2w ago

Zhen Liu, Dai Shi, Yue Cai, Anqi Li, Guoyu Lan, Pan Sun, Lin Liu, Yalin Zhu, Jie Yang, Yajing Zhou, Lizhi Guo, Laihong Zhang, Shuqing Deng, Shuda Chen, Xianfeng Yu, Xuhui Chen ..read more

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Who am I with my Lewy bodies? The insula as a core region of the self-concept networks

Alzheimer's Research & Therapy

2w ago

Alice Tisserand, Frédéric Blanc, Mary Mondino, Candice Muller, Hélène Durand, Catherine Demuynck, Paulo Loureiro de Sousa, Alix Ravier, Léa Sanna, Anne Botzung and Nathalie Philippi ..read more

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