
Creative Biolabs Vaccine Blog
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Creative Biolabs is the leading custom service provider that has extensive experience in various antibody production and engineering fields.Our service portfolio includes mouse and rat monoclonal antibody production using hybridoma technology, human, monkey, rabbit, chicken, dog, llama and camel monoclonal antibody production using various antibody library technologies. Know more about our..
Creative Biolabs Vaccine Blog
3w ago
Introduction Vaccines have transformed public health, limiting infectious disease spread and saving millions of lives worldwide. mRNA vaccines, by which medical science developed a method of vaccination without losing effectiveness, have made itRead More ..read more
Creative Biolabs Vaccine Blog
1M ago
Vaccines are the most successful public health measure ever, halting the spread of infectious diseases and slowing some of the worst disease ever seen in the vast majority of the world. AsRead More ..read more
Creative Biolabs Vaccine Blog
2M ago
mRNA vaccines are one of the best medical and immunological discoveries of the past few years. While vaccines themselves aren’t exactly new, mRNA technology flips the script on how we think about immunization.Read More ..read more
Creative Biolabs Vaccine Blog
6M ago
The team of Professor Michael J. Mitchell of the University of Pennsylvania and Professor Drew Weissman, winner of the 2023 Nobel Prize in Physiology and Medicine, published a review paper titled “EnhancingRead More ..read more
Creative Biolabs Vaccine Blog
7M ago
Recently, the journal Nature Biomedical Engineering published a research paper titled “Dendritic-cell-targeting virus-like particles as latent mRNA vaccine carriers” about a new vaccine platform technology that can specifically target dendritic cells (DCs) and efficiently deliver mRNA and protein—DC-targeted viroid vector (DVLP).
This brand-new vaccine technology can not only carry mRNA but also display the three-dimensional structure of antigenic proteins on the surface of vaccine particles. It has the ability to effectively activate humoral immunity and cellular immunity and can significantl ..read more
Creative Biolabs Vaccine Blog
8M ago
In a first-of-its-kind human clinical trial involving four adult patients, an mRNA cancer vaccine developed by the University of Florida rapidly reprograms the immune system to attack glioblastoma, the most aggressive and deadly brain tumor.
These results reflect the treatment outcomes of 10 pet dogs with naturally occurring brain tumors, whose owners agreed to participate in the treatment as they had no other options, as well as the results of a preclinical mouse model. This breakthrough will now be tested in a pediatric phase 1 clinical trial for the treatment of brain cancer. The findings w ..read more
Creative Biolabs Vaccine Blog
10M ago
Gamma delta (γδ) T cells are a type of innate-like T cell that possess dual anti-tumor activities, capable of directly eliminating tumor cells and acting as immunostimulatory cells to enhance the body’s anti-tumor immunity. In a recent research report titled “Tumor vaccine based on extracellular vesicles derived from γδ-T cells exerts dual antitumor activities” published in the international journal Journal of Extracellular Vesicles, scientists discovered that extracellular vesicles (exosomes) derived from γδ-T cells not only exhibit direct anti-tumor effects but also, if developed into a tumo ..read more
Creative Biolabs Vaccine Blog
1y ago
Vaccination is undoubtedly one of the most remarkable health achievements in human history. In just over two centuries, vaccines have enabled us to achieve extraordinary goals, such as eradicating smallpox, eradicating polio from most parts of the world, and dramatically reducing mortality and morbidity from many infectious diseases.
Vaccination policies are the cornerstone of public health, and there is a strong emphasis on ensuring safe and effective vaccines. The effectiveness of the vaccine depends not only on the antigenic composition, but also on the adjuvants that are often used, stimul ..read more
Creative Biolabs Vaccine Blog
1y ago
The development of effective vaccines for infectious diseases is one of the most successful global health interventions ever. Although subunit vaccines largely depend on the selection of antigens and adjuvants, the exposure modes and time scales of the immune system are often overlooked. Adjuvants play a crucial role in enhancing the quality and efficacy of immune responses, but unfortunately, poor control over the delivery of many adjuvants can limit their efficacy and lead to off-target toxicity. Therefore, there is an urgent need to improve adjuvant delivery technologies to improve the effi ..read more
Creative Biolabs Vaccine Blog
1y ago
The trend in the field of cancer immunotherapy is the use of cancer vaccines. By using identified tumor antigens to stimulate the immune system, cancer vaccines can generate a specific immune response against tumor cells, thus causing the destruction of these cells and preventing recurrences and metastasis. Recently, a research team led by Zhao Xiao and Nie Guangjun at the National Center for Nanoscience and Technology of the Chinese Academy of Sciences proposed a strategy dubbed “peri-vaccination immune priming,” which involves enhancing the immune system through the use of bacterial nanopart ..read more