Single-Cell Transcriptomic Analysis Uncovers Diverse and Dynamic Senescent Cell Populations
Aging
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1w ago
“In summary, single-cell transcriptomic analysis has allowed us to identify the specific populations and the dynamic transition states during senescence initiation and progression ..read more
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An Epigenetic Approach to Modulating Aging With Nutrition and Exercise
Aging
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1w ago
“In this review, we describe how aging impacts epigenetics and how nutrition and physical exercise can positively impact the aging process, from an epigenetic point of view ..read more
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Effects of Zoledronic Acid on Senescence and SASP Markers
Aging
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1w ago
“In the present study, we used multiple complementary approaches to evaluate the possible effects of zoledronic acid on cellular senescence ..read more
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Musashi 1 in Breast Cancer: Implications for Dormancy and Survival in Bone Marrow
Aging
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1w ago
“This study now links Msi 1 to PD-L1 ..read more
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A Chronic Wound Model to Investigate Skin Cellular Senescence
Aging
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2w ago
“Here, we report a chronic wound healing model that can be used to decipher the paradoxical role of cellular senescence in acute versus chronic wound healing ..read more
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Serine Racemase Upregulation Improves Learning and Synaptic Function
Aging
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1M ago
“The results from this study support the beneficial effects of the D-serine pathway involvement in NMDAR-mediated transmission and cognitive function ..read more
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Characterization of the HDAC/PI3K Inhibitor CUDC-907 as a Novel Senolytic
Aging
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1M ago
“The mechanisms of induction of senescent cell death by CUDC-907 remain to be fully elucidated ..read more
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Effect of Deferoxamine and Ferrostatin-1 on Salivary Gland Dysfunction in Ovariectomized Rats
Aging
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1M ago
“[...] this study is expected to be helpful in [...] developing a treatment for postmenopausal dry mouth ..read more
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Knockout of AMD-Associated Gene POLDIP2 Reduces Mitochondrial Superoxide in Retinal Cells
Aging
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1M ago
“To our knowledge, this is the first functional study of POLDIP2 in retinal cells to understand its potential role in AMD ..read more
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Selenium as a Predictor of Metabolic Syndrome in Middle Age Women
Aging
by
1M ago
“Recently, optimizing selenium intake in the population to prevent diseases [...] has been an important issue in modern health care worldwide ..read more
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