New 3D genomic profiling technique details PanINs
Drug Target Review » Chemotherapy
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3w ago
Researchers have developed a 3D approach to improve the characterisation of pancreatic intraepithelial neoplasias ..read more
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Using AI to predict metastatic behaviour of NSCLC
Drug Target Review » Chemotherapy
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3M ago
Dr Richard Cote and Dr Ramaswamy Govindan of the Washington University School of Medicine elucidate how AI, particularly deep learning networks, could identify histopathologic features in non-small cell lung cancer, and impact the treatment approach for early-stage patients. Dr Ramaswamy Govindan (Washington University School of Medicine) Dr Richard Cote (Washington University School of Medicine ..read more
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B-ALL: combination therapy effectively controls high-risk subtypes
Drug Target Review » Chemotherapy
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3M ago
The combination therapy worked faster and was lessened the number of leukaemia cells compared to asparaginase or venetoclax alone ..read more
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Reversing malignant cancer cells to a normal state
Drug Target Review » Chemotherapy
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3M ago
A new proof-of-principle study demonstrates the DCAF5 protein is a promising target, which could avoid the need for toxic therapies ..read more
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Potential for personalised, molecularly guided UTUC treatments
Drug Target Review » Chemotherapy
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4M ago
The findings from DNA and RNA sequencing in primary and metastatic UTUC tumours could lead to strategies to improve patient outcomes ..read more
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Transforming cancer treatment for greatest impact
Drug Target Review » Chemotherapy
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5M ago
In this Q&A, Dr Lev Becker, Associate Professor, University of Chicago and Cofounder of Onchilles Pharma, reveals how his company is directing research into neutrophil biology to the advantage of cancer patients that need it most ..read more
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New algorithm can predict when cancer will resist chemotherapy
Drug Target Review » Chemotherapy
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5M ago
The ML algorithm explores how genetic mutations collectively influence a tumour’s reaction to drugs impeding DNA replication ..read more
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The potential of PD-L2 inhibitors for cancer treatment
Drug Target Review » Chemotherapy
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5M ago
Researchers discover that blocking PD-L2 in senescent cells increases the efficacy of chemotherapy in mouse models ..read more
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How the DA subtype of Wilms tumour resists chemotherapy
Drug Target Review » Chemotherapy
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5M ago
Researchers suggest that DA histology slowly emerges by accumulating burdens of DNA damage and copy number aberrations ..read more
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Organoid drug testing predicts bowel cancer treatment response
Drug Target Review » Chemotherapy
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5M ago
A new study proves that organoid drug testing is highly accurate at predicting effective treatments and finds a novel therapeutic option ..read more
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