My oxalate story - from high sensitivity to tolerance
Gutsy By Nutrition Blog » Gut Health
by Gutsy by Nutrition
3d ago
cutting out oxalates vs healing the body Most people resolve oxalate sensitivity by cutting out oxalates. They look to the external source. But not me. I’m always asking why is someone sensitive to oxalates, and what can be done to allow greater food freedom, and actually, better health at the same time. I know that reducing oxalate intake works to an extent by reducing our oxalate load. But I also know that our own body continues to create them due to dysfunction, putting us constantly at the edge of our oxalate tipping point. Then there’s genetics. I have all the genetics for oxalate sensiti ..read more
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How to get around antibiotic resistance
Gutsy By Nutrition Blog » Gut Health
by Gutsy by Nutrition
3d ago
Antibiotic resistance occurs when some of the trillions of microorganisms there develop mechanisms to withstand the effects of antibiotics, rendering them partially or entirely ineffective in treating bacterial infections. These are the mechanisms Gene Transfer – Bacteria in the gut microbiome can exchange genetic material through various processes. This horizontal gene transfer enables the spread of antibiotic resistance genes among bacterial species, including pathogens, normal and beneficial bacteria Selective Pressure – Antibiotic exposure favours the survival and proliferation of ant ..read more
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Is it possible to 'switch off' the gene involved in halitosis?
Gutsy By Nutrition Blog » Gut Health
by Gutsy by Nutrition
6d ago
about FMO3 & halitosis The FMO3 gene plays a crucial role in extra-oral halitosis, particularly in a condition known as trimethylaminuria (TMAU).  The FMO3 gene, which encodes the enzyme flavin-containing monooxygenase 3 (FMO3), can be affected by various factors that can either reduce its expression or inhibit its activity. These factors can be genetic, epigenetic (external like environmental), or pharmacological in nature. Here are some key factors that can switch off or down-regulate the FMO3 gene. factors that impact fmo3 expression Genetics FMO3 and other genetics impacting halit ..read more
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What hinders bio-transformation (detoxification)?
Gutsy By Nutrition Blog » Gut Health
by Gutsy by Nutrition
1w ago
what is biotransformation? Biotransformation, or metabolism, is the chemical modification of substances within the body to make them more easily excreted. This is important for detoxification, nutrient metabolism, hormone regulation, drug metabolism and the elimination of waste products. Factors that can compromise bio-transformation (detoxification) Biotransformation and detoxification pathway impairment e.g. low amino acids, genetic variants like COMT, CYP, MTHFR), fatty liver, poor gallbladder function Inadequate methylation e.g. insufficient B vitamins caused by low stomach acid or dig ..read more
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Nutrient shortages can increase your own body's production of oxalates
Gutsy By Nutrition Blog » Gut Health
by Gutsy by Nutrition
2w ago
Nutrient shortages can increase endogenous (your own body's) production of oxalates, as opposed to getting from food. Here's how nutrient shortages increase oxalate production in the body Glyoxylate – is an oxalate precursor. Its metabolism is tightly regulated to prevent oxalate accumulation. Inadequate levels of nutrients like B6 and magnesium (common) can impair the activity of enzymes involved in glyoxylate metabolism, leading to an accumulation of glyoxylate, which can be converted to oxalate Mitochondria – play a critical role in energy production and other metabolic (conversion) pr ..read more
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Low stomach acid causes histamine issues
Gutsy By Nutrition Blog » Gut Health
by Gutsy by Nutrition
3w ago
Low stomach acid, or hypochlorhydria, can lead to histamine problems through numerous mechanisms: Increased Bacterial Overgrowth – Stomach acid acts as a barrier to prevent bacterial overgrowth in the stomach and small intestine. Low stomach acid can lead to bacterial overgrowth, including bacteria that produce histamine. This can result in higher levels of histamine in the gut. Impaired Protein Digestion – Adequate stomach acid is essential for the proper digestion of protein. When stomach acid is low, protein may not be fully broken down, leading to the accumulation of partially digeste ..read more
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Which gut bacteria can contribute to halitosis?
Gutsy By Nutrition Blog » Gut Health
by Gutsy by Nutrition
1M ago
Halitosis, gut bacteria & TMA Several gut bacteria are known to produce trimethylamine (TMA). Trimethylamine is an organic compound that has a strong, fishy odor. It is produced in the body through the digestion of certain nutrients, particularly choline and carnitine, which are found in foods like eggs, liver, fish and legumes. Gut bacteria play a key role in converting these nutrients into TMA by metabolising dietary compounds like choline and carnitine. TMA is then absorbed into the bloodstream and processed by the liver enzyme called flavin-containing monooxygenase 3 (FMO3). Here are s ..read more
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The connection between your stomach & high oxalates
Gutsy By Nutrition Blog » Gut Health
by Gutsy by Nutrition
1M ago
The relationship between a damaged stomach lining, low stomach acid (hydrochloric acid or HCl), and high oxalates involves several inter-connected physiological processes. In short, by addressing both low stomach acid and (an often consequent) damaged stomach lining, it’s possible to reduce oxalate issues, and support overall digestive and systemic health. Low Stomach Acid (Hypochlorhydria) & Oxalate Absorption Adequate stomach acid is crucial for the absorption of minerals like calcium and magnesium. These minerals can bind to oxalates in the gut, forming insoluble compounds that are e ..read more
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I did a gut protocol & now I feel worse
Gutsy By Nutrition Blog » Gut Health
by Gutsy by Nutrition
1M ago
Feeling worse after doing a gut protocol? Whether it was drug or natural medicine based, professionally guided or self-guided, I get plenty of clients coming to me with this issue. What went wrong? The eradication of gut infections (microbial, fungal/yeast, parasitic) using drugs or natural medicine often decreases beneficial or commensal gut bacteria ie it kills off the good along with the bad Beneficial bacteria protect against harmful microbes or dysbiosis (imbalances) by competing for resources, producing antimicrobial substances and supporting gut barrier function. Their reduction lea ..read more
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These probiotics can lower histamine levels
Gutsy By Nutrition Blog » Gut Health
by Gutsy by Nutrition
1M ago
While some probiotic species can increase histamine levels in susceptible individuals, others have histamine-lowering effects such. some probiotic strains that lower histamines Bifidobacterium infantis 35624, DSM 33361 – Reduce histamine levels, may modulate immune responses and reduce gut inflammation Bifidobacterium longum BB536, Rosell-175 – May be anti-inflammatory and lower histamines in the gut Lactobacillus rhamnosus GG (LGG), HN001, GR-1 – Possible anti-inflammatory properties and mitigate histamine symptoms Lactobacillus plantarum 299v, DSM 9843 – Can modulate immune response ..read more
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