KarXT Effective in Improving Schizophrenia Symptoms at 52 Weeks
HCPLive » Schizophrenia
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2d ago
EMERGENT-3 trial showed xanomeline-trospium was effective in improving schizophrenia symptoms at 52 weeks, for participants who took either placebo or KarXT in acute trials ..read more
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Phase 3 Data Shows Pimavanserin for Schizophrenia is No Better Than Placebo
HCPLive » Schizophrenia
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1M ago
Acadia Pharmaceuticals decided to stop conducting further clinical trials with pimavanserin for negative symptoms of negative due to topline results ..read more
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FDA Issues CRL for Roluperidone for Treatment of Negative Symptoms in Schizophrenia
HCPLive » Schizophrenia
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1M ago
Minerva Neurosciences announced the receipt of a Complete Response Letter for roluperidone in treatment of negative symptoms in patients with schizophrenia on February 27, 2024 despite clinical trial data indicating improved Negative Symptom Factor Scores and Personal and Social Performance scale scores ..read more
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Antipsychotic Injections for Schizophrenia Linked to Decline in Hospital Readmissions
HCPLive » Schizophrenia
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2M ago
In a study comparing readmission rates for patients with schizophrenia or schizoaffective disorder on oral or long-acting injections, investigators found after 30 days the readmission rate was 8.3% among patients who received pills and 1.9% among patients who received injections ..read more
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Psychiatry Month in Review: January 2024
HCPLive » Schizophrenia
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2M ago
Our January 2024 psychiatry month in review includes studies finding associations with depression, anxiety, and anorexia nervosa, as well as a phase 3 study looking into long-term safety of olanzapine, samidorphan ..read more
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Lurasidone Linked to Improving Social Functioning for Schizophrenia
HCPLive » Schizophrenia
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2M ago
A new study found patients with schizophrenia on lurasidone had an effect size change of 0.33 on the PANSS prosocial subscale, suggesting improvements in social functioning ..read more
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Young Adults at Greater Risk of Adverse Events with Clozapine than Older Adults
HCPLive » Schizophrenia
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2M ago
A new study found individuals aged 18 – 55 with treatment-resistant schizophrenia had significantly greater adverse events than individuals aged ≥ 55 years ..read more
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Jacob Ballon, MD, MPH: Discusses Takeaways from Studying Long-Term Olanzapine and Samidorphan
HCPLive » Schizophrenia
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3M ago
In an interview, Jacob Ballon, MD, MPH, discusses the significance of his team’s study which found olanzapine and samidorphan was well-tolerable for up to 4 years of treatment for schizophrenia and bipolar disorder treatment ..read more
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Olanzapine, Samidorphan Effective for Long-Term Schizophrenia, Bipolar Disorder Treatment
HCPLive » Schizophrenia
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3M ago
A study demonstrated olanzapine and samidorphan’s (LYBALVI) safety, tolerability, and durability during a 4-yeat treatment period ..read more
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Peer-Reviewed EMERGENT-2 Trial Data Supports Xanomeline-Trospium for Schizophrenia
HCPLive » Schizophrenia
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4M ago
In a phase 3 EMERGENT-2 trial, the study found 55% of participants with schizophrenia taking xanomeline-trospium had a ≥30% improvement from baseline to week 5, compared to the placebo group ..read more
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