Ultra-low-dose ketamine can curb opioid withdrawal
ScienceDaily » Pharmacology
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6h ago
A pilot study showed that a small amount of ketamine can reduce or eliminate the withdrawal symptoms associated with quitting fentanyl ..read more
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Team discovers naturally occurring DNA-protein hybrids
ScienceDaily » Pharmacology
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6h ago
Thanks to a serendipitous discovery and a lot of painstaking work, scientists can now build biohybrid molecules that combine the homing powers of DNA with the broad functional repertoire of proteins -- without having to synthesize them one by one, researchers report. Using a naturally occurring process, laboratories can harness the existing molecule-building capacities of bacteria to generate vast libraries of potentially therapeutic DNA-protein hybrid molecules ..read more
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Cow slime can help disc herniation patients after surgery, research shows
ScienceDaily » Pharmacology
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6h ago
Researchers have developed a gel inspired by cow slime for patients suffering from disc herniation. By adding the mucin gel immediately after surgery, it is possible to create a protective barrier around the discs to prevent the immune system from attacking their nucleus pulposus. This keeps the discs intact and reduces the risk of further damage ..read more
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Cancer cells may be using lipids to hide from the immune system
ScienceDaily » Pharmacology
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1d ago
New study demonstrates that one type of lipid is so critical for immune evasion that certain cancers cannot proliferate without them. Modulating intake of dietary lipids could open up an avenue for treatment ..read more
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Risk of clots, stroke from incorrect blood thinner dosing reduced using online dashboard
ScienceDaily » Pharmacology
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1d ago
Doctors and pharmacists treating people with blood thinners can reduce the rate of inappropriate dosing -- as well as blood clots and strokes that can result from it -- using an electronic patient management system, a study suggests. Direct oral anticoagulants can be incorrectly prescribed up to 20% of the time ..read more
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New treatment extends ovarian function in older mice
ScienceDaily » Pharmacology
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1d ago
Scientists have discovered a novel way to lengthen the 'healthspan' of a women's ovaries -- improving maintenance of the ovaries and preventing key age-related changes in ovarian function. 'Healthspan' refers to the length of time a person remains healthy and free from serious illness or chronic diseases ..read more
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CREME AI and CRISPR in tandem
ScienceDaily » Pharmacology
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2d ago
CREME is a virtual laboratory that allows scientists to simulate specific decreases in gene activity. It offers a powerful new tool for identifying and understanding important parts of the genome. And it could one day give scientists who don't have access to real laboratories the power to make breakthrough discoveries ..read more
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Monoclonal antibodies offer hope for tackling antimicrobial resistance
ScienceDaily » Pharmacology
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2d ago
Monoclonal antibodies -- treatments developed by cloning a cell that makes an antibody -- could help provide an answer to the growing problem of antimicrobial resistance, say scientists ..read more
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Experimental mRNA cancer vaccine shows potential for advanced stage cancer patients in Phase 1 trial
ScienceDaily » Pharmacology
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5d ago
Interim data from the Phase I dose escalation part of the mRNA cancer immunotherapy (mRNA-4359), show promise in patients with advanced solid cancers. The investigational mRNA cancer immunotherapy is targeted for patients with lung cancer, melanoma and other solid tumours. Nineteen patients with advanced stage cancers received between one and nine doses of the immunotherapy treatment. Scientists have found the immunotherapy created an immune response against cancer and was well tolerated, with adverse events including fatigue, injection site pain and fever ..read more
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Key factors that impact long-term weight loss in patients prescribed GLP-1 RA medications
ScienceDaily » Pharmacology
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5d ago
A new study identified key factors that can impact the long-term weight loss of patients with obesity who were prescribed injectable semaglutide or liraglutide for the treatment of type 2 diabetes or obesity ..read more
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