Understanding how the knee joint environment affects cartilage cells is crucial for joint health. Knowledge of cell-driven cartilage degeneration mechanisms can support the development of effective pharmaceutical interventions for osteoarthritis. Researchers have now incorporated the influence of cells in a new numerical model to discover degeneration processes in mechanically loaded and inflamed cartilage ..read more

Strengthening hip muscles could be key to improve mobility in people with a below-the-knee amputation, new research has shown ..read more

Scientists delved into the relationship between gait function and knee extension velocity after total knee arthroplasty and compared the effects of various factors on walking. The results reveal that knee extension velocity, measured while seated, on the operated side was the most important determinant of gait function. These findings are expected to contribute to the development of new rehabilitation programs for efficient gait function improvement ..read more

Large doses of opioids are commonly prescribed after total knee and hip arthroplasty to avoid call-ins for refills, but smaller doses can be just as effective ..read more

A new study has identified that Talarozole, a drug that is known to increase retinoic acid, was able to prevent osteoarthritis (OA) in disease models ..read more

Researchers have developed an AI based neural network to detect an early knee osteoarthritis from x-ray images. AI was able to match a doctors' diagnosis in 87% of cases. The result is important because x-rays are the primary diagnostic method for early knee osteoarthritis. An early diagnosis can save the patient from unnecessary examinations, treatments and even knee joint replacement surgery ..read more

Scientists identify a new molecular model and potential therapeutic target for gout, the most common form of inflammatory arthritis ..read more

Commonly used drugs that reduce joint inflammation in patients with rheumatoid arthritis also reduce vascular inflammation and cardiovascular risk, finds a new study ..read more

Competing at elite level in sport is linked with an increased risk of developing osteoarthritis and joint pain in later life, a study suggests. One in four retired Olympians reported a diagnosis of osteoarthritis, the form of arthritis that causes changes in the joint and can lead to discomfort, pain and disability, the research found ..read more

So far, there no uniform guidelines have existed for the treatment of arthritis of the jaw, a potentially debilitating consequence of juvenile arthritis ..read more