A team of researchers at the Keck School of Medicine of USC have found a drug with the potential for curbing painful hyperinflammation from osteoarthritis, according to results of an animal study ..read more

Arthritis in the knee's patellofemoral joint (PFJ) is common following anterior cruciate ligament reconstruction (ACLR) and may be linked with altered loading, or stress, at the joint. In a study published in the Journal of Orthopaedic Research, young adults post‐ACLR who exhibited lower PFJ loading during hopping were more likely to have PFJ osteoarthritis at 1‐year and worsening PFJ osteoarthritis between 1‐ and 5‐years ..read more

Knee osteoarthritis (OA) is the most common form of arthritis worldwide, affecting more than 500 million people worldwide and 34 million people in the U.S. There are no treatments available that prevent its progression and recommended pharmacological treatments and other treatments (exercise, weight loss) have either small-to moderate effects or short-term effects. As such, knee replacement (KR) is considered one of few therapies that can considerably improve pain and function in patients with severe, end-stage knee OA ..read more

A new blood test that can identify progression of osteoarthritis in the knee is more accurate than current methods, providing an important tool to advance research and speed discovery of new therapies ..read more

"Speed or strength, which is more important?" This may be a critical question not only for athletes, but also knee surgery patients. Osaka Metropolitan University scientists have revealed that knee extension velocity while seated is a stronger predictor of walking performance than muscle strength in elderly patients after their total knee arthroplasty (TKA) surgery ..read more

A Michigan Medicine study has identified a new potential target for treating osteoarthritis—a debilitating joint disease that affects over 31 million Americans and is a leading cause of disability worldwide ..read more

Researchers in the United States and Japan have discovered a new mechanism that links age-related cartilage tissue stiffening with the repression of a key protein associated with longevity. These findings enhance the understanding of mechanisms that lead to the deterioration of joints that causes osteoarthritis, according to the authors of a new study, published January 10th in Nature Communications ..read more

For selected patients with knee osteoarthritis, unicompartmental (or "partial") knee arthroplasty (UKA) shortens the recovery time for two key measures of physical function, as compared with total knee arthroplasty (TKA), reports a randomized trial in The Journal of Bone & Joint Surgery ..read more

Osteoarthritis is a common chronic condition that usually causes joint pain and can be severe enough to require knee and hip replacements. In the United States, the number of total knee replacement (TKR) and total hip replacement (THR) surgeries is estimated to reach 572 000 per year by 2030. No medications are currently known to prevent or reverse osteoarthritis ..read more

For overweight or obese patients with knee osteoarthritis, diet and exercise result in a small but statistically significant difference in knee pain over 18 months compared with an attention control, according to a study published in the Dec. 13 issue of the Journal of the American Medical Association ..read more