Is the future of medicine sweetened by the study of glycans? As GlycanHub rounds off its season, we've brought back the insights of 11 eminent scientists spanning from neuroscience to nanotechnology. Each guest delves into their vision of how glycans could shape medical advancements in their respective fields. Join Rina, our host, for a grand finale that paints a holistic picture of the promising horizon glycobiology is steering us towards. Answers to the question: What role do you think glycans will play in the future of medicine relevant to your area of study?  Salome Pinho [01:21] &nb ..read more

Could your steak dinner be tricking your immune system? In this episode we shed light on the connection between specific foods and colorectal cancer. Explore xeno-autoantigens, grasp the nuances of immunotherapy, and question the reliability of animal-derived heart valves. Vered Padler-Karavani is the principal investigator in the Department of Cell Research and Immunology at Tel Aviv University. Her research combines glycobiology, immunology, bio-nanotechnology, cancer research and xenotransplantation. Tune in to uncover the hidden connections between glycans, our diet, and the potential heal ..read more

Does menopause hold implications beyond reproductive health? This episode reveals that the shift in hormonal balance affects inflammatory patterns, mediated by complex carbohydrates called glycans. We unravel the overlooked role of perimenopause in chronic disease onset and debunk common myths. Exploring hormone replacement therapy, we discuss its wider health impact, beyond mere symptom management. Louise Newson, a distinguished GP and Menopause Specialist, is the founder of the Balance App, The Menopause Charity, and the Newson Health Menopause Society. An active member of the UK Government ..read more

In an era defined by COVID-19, understanding the intricacies of our immune response and the profound role our lifestyle choices play in shaping our resilience or vulnerability to future pandemics is of great importance. In this episode, we unravel the influence of glycans, complex carbohydrates instrumental in immune response regulation, on our understanding of COVID-19 susceptibility and severity. We explore the role of lifestyle in disease prevention, particularly focusing on diet and obesity. Gordan Lauc is a Professor of Biochemistry and Molecular Biology at the University of Zagreb Facult ..read more

The longer lifespans we enjoy come shadowed by age-related diseases, notably Alzheimer's. This episode shines a light on the often-overlooked glycans, complex carbohydrates that play a pivotal role in healthy brain function. Our understanding of Alzheimer's causation has evolved, moving beyond just 'trash accumulation' to include problems with 'trash clearance.' Discover the potential of glycans in healing spinal cord injuries, the hurdles in identifying early biomarkers and delivering drugs to the brain. We delve into the essential role of gangliosides, a unique class of glycolipids, and sepa ..read more

Are you ready to journey through the intricate layers of Omics, a rapidly developing field that's reshaping our understanding of biological systems? From genomics to proteomics and metabolomics, the multi-omics approach intertwines these layers, offering a rich, multidimensional view of human biology. Today's conversation unravels the fascinating complexity within our bodies, spotlighting the current advancements in multi-omics research and its transformative potential in disease diagnosis and treatment. You'll also discover why glycans, despite often being overlooked in multi-omics studies, a ..read more

The concept of biological age might sound like a new notion, but it’s something researchers have been looking at for 35 years. A person’s biological age can tell us more about them than chronological age because it includes genetics, lifestyle and environmental factors. Since it’s such an individualised metric, it’s important to find a reliable way of measuring it. In the episode, Rina and her guest Dr Peter Joshi describe 11 different biological ageing clocks, the research behind them and why GlycanAge is such a great tool for providing not just an accurate measurement of your biological age ..read more

Menopause is no laughing matter, but having humour about it might be the key to breaking down the stigma.  In order to celebrate World Menopause Day, we’re bringing you an uplifting interview with Suzzane Parkes - a person near and dear to all of us in GlycanAge. Suzanne is a consultant that spent her career in the fitness industry and has always prioritized a holistic approach to her health.  Suzanne is passionate about sharing her menopause journey in order to prevent future generations from suffering the way she has. Her vulnerability has helped us prepare an amazing episode which ..read more

Have you ever heard that “Art is I and science is we”? This is a great sentence to introduce our new episode in which we cover the topics of:  Proactive cancer treatment  Using mice models in cancer research The First Cell Center  How big of an impact cancer can leave on a family,  and so much more.   We’re excited to introduce our guest Dr Azra Raza, who is a Professor of Medicine and the Director of the MDS Center at Colombia University in New York. She is an accomplished scientist who supervises a state-of-the-art basic research lab and a Tissue Repository of b ..read more

Is it enough to conduct medical research only on white men? Why are women more affected by autoimmune diseases? Do menopause and pregnancy trigger different ailments? Is there such a thing as a male and a female hormone?  In this episode of The Age of You - a sweet secret to longevity, we discuss male-centric medicine and the effects created by the exclusion of women in medical research.  Our guests are DR Alka Patel, a TEDx speaker, GP, lifestyle doctor, longevity coach, author, podcaster, the founder of Lifestyle First, a platform that helps people change their lifestyles for the b ..read more