Researchers create new platform to identify proteins for targeted treatment of disease
News Medical » Chronic Myeloid Leukemia
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1M ago
Researchers at the University of Toronto and Sinai Health have created a new platform to identify proteins that can be co-opted to control the stability of other proteins -; a new but largely unrealized approach to the treatment of disease ..read more
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Novel assay may improve detection and treatment of acute myeloid leukemia
News Medical » Chronic Myeloid Leukemia
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6M ago
A novel assay that detects a unique molecular marker in patients with acute myeloid leukemia (AML) may revolutionize the way this disease is detected and treated according to a new report in The Journal of Molecular Diagnostics published by Elsevier ..read more
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New study highlights risks of anti-ERBB2 cancer drugs during pregnancy
News Medical » Chronic Myeloid Leukemia
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6M ago
Study finds that anti-ERBB2 inhibitors used in breast cancer treatment pose significant risks to pregnancy and fetal health, including higher likelihoods of congenital defects and intrauterine growth restriction. Researchers recommend careful monitoring and possibly discontinuing these drugs during pregnancy despite their effectiveness against cancer ..read more
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Annual NCCN Congress to focus on latest advances in blood cancer treatment
News Medical » Chronic Myeloid Leukemia
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8M ago
The National Comprehensive Cancer Network 2023 Annual Congress: Hematologic Malignancies returns to San Francisco this week, for the first time since 2019 ..read more
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ECOG-ACRIN launches new trial to evaluate nilotinib and paclitaxel for advanced cancers
News Medical » Chronic Myeloid Leukemia
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10M ago
The ECOG-ACRIN Cancer Research Group has enrolled the first patient in a new treatment trial to evaluate the effectiveness of adding nilotinib to standard paclitaxel chemotherapy ..read more
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PREACH-M trial: Lenzilumab may improve treatment response in chronic myelomonocytic leukemia
News Medical » Chronic Myeloid Leukemia
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11M ago
Humanigen, Inc.today extended previously reported results by presenting additional, statistically significant hematologic improvements and reductions in inflammatory markers from lenzilumab, its investigational drug, in a Phase 2/3 trial of treatment-naïve participants with chronic myelomonocytic leukemia and RAS-pathway mutations ..read more
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Mast cells play a crucial role in the development of chronic myeloid leukemia
News Medical » Chronic Myeloid Leukemia
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1y ago
Chronic myeloid leukemia (CML) is a type of blood cancer that arises from malignant changes in blood-forming cells of the bone marrow ..read more
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Small molecule inhibitor reverses malignant hyper-editing by an inflammation-induced protein isoform
News Medical » Chronic Myeloid Leukemia
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1y ago
Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called rebecsinib, reverses malignant hyper-editing by an inflammation-induced protein isoform, known as ADAR1 p150 ..read more
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Protein degradation approach can be used to hit an ‘undruggable’ target against cancer
News Medical » Chronic Myeloid Leukemia
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1y ago
The protein STAT5 has long been an appealing target against cancer, but after decades of research it was consigned to the "undruggable" category ..read more
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Targeted therapies and novel drug combinations show promise for the treatment of multiple leukemias
News Medical » Chronic Myeloid Leukemia
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1y ago
Researchers from The University of Texas MD Anderson Cancer Center are presenting compelling findings from three clinical trials at the 2022 American Society of Hematology Annual Meeting ..read more
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