
MedEvidence! Truth Behind the Data
156 FOLLOWERS
Welcome to the MedEvidence podcast, hosted by Dr. Michael Koren and Michelle McCormick. MedEvidence, where we help you navigate the real truth behind medical research with both a clinical and research perspective. In this podcast, we will have discussions with physicians that have extensive experience in patient care and research. How do you know that something works? In medicine, we conduct..
MedEvidence! Truth Behind the Data
4d ago
Send us a text
Join Pulmonologist Dr. Mitchell Rothstein and Allergist and Immunologist Dr. Steve Dorman as they explore the violent activity that can project particles at 100 miles an hour out of your mouth: coughing! The doctors explain the varied approaches doctors take when trying to find the cause of a cough and what happens inside the body to turn a cough from productive to chronic. They explore things that can stimulate a coughing event and review what medications are currently approved for chronic cough. Finally, the two doctors discuss the possibility of new medications being develope ..read more
MedEvidence! Truth Behind the Data
1w ago
Send us a text
Technology like Artificial Intelligence (AI) is being integrated more and more into our lives. It's fast, convenient, and can be used at home to gather more health data than ever. But how do we know if the benefits of these technologies outweigh potential risks and pitfalls?
Dr. Mike Hafran joins Dr. Michael Koren to discuss how clinical trials can and have been used to weigh the risks and benefits of new medicines in the past and how clinical trials need to be applied to emerging healthcare technologies (and newly categorized medicines like cannabis) before they are integ ..read more
MedEvidence! Truth Behind the Data
1w ago
Send us a text
This episode focuses on the FDA's approval of Journavx, a new class of pain medication that offers an alternative to traditional narcotics like OxyContin. Listeners learn about the significance of clinical trials, patient involvement, and the evolution of pain management strategies while emphasizing the need for informed discussions with healthcare providers.
• Introduction to Jernovex and its pain management potential
• Importance of clinical trials in drug development
• Discussion on the practical implications for patients
• Shift in medical policy arou ..read more
MedEvidence! Truth Behind the Data
1w ago
Send us a text
In this second and final part of this series, Dr. Michael Koren and Dr. Seth Baum discuss the importance of patient retention in cardiovascular clinical trials. They highlight how participants in these trials, even those on placebos, often experience better health outcomes due to increased medical attention. They stress the need for clear communication at the outset, proper participant selection, and continued engagement through education and personal interactions. Dropping out of a trial can negatively impact the study’s validity and broader medical advancements.
Dr. Kor ..read more
MedEvidence! Truth Behind the Data
1w ago
Send us a text
The trajectory for those with cardiovascular disease has changed drastically in the past few decades. Cardiologists Michael Koren and Seth Baum discuss the amazing 60% drop in cardiovascular mortality since the 1980's and the worrying rebound in heart-related mortality starting around 2012. They dissect various influences for both of these trends, including changes in diet, a widespread drop in medical compliance, and wavering public opinion on heart medicines like statins.
Dr. Koren and Dr. Baum then dive into some potential ways to tackle the worrying recent trend, including ..read more
MedEvidence! Truth Behind the Data
2w ago
Send us a text
Dr. Michael Koren reflects on his interview with Dr. Anthony Fauci with Kevin Geddings. This episode explores Dr. Fauci's history in public health and his life after exiting the government sphere. Dr. Koren and Kevin Geddings also highlight the importance of acknowledging uncertainties in science, and how other fields don't always have the same clarity and transparency as medicine.
A key takeaway is the MedEvidence! approach: identifying what is known, unknown, and how to learn more. This honest perspective underscores the value of evidence-based medicine, public tr ..read more
MedEvidence! Truth Behind the Data
2w ago
Send us a text
Join Dr. Anthony Fauci and Dr. Michael Koren as they discuss the public health events that have punctuated Dr. Fauci's life. The doctors discuss the difficulties of the HIV epidemic in the 1980's and how Dr. Fauci's early career decision to pursue this emerging threat helped inform and prepare him for the COVID-19 pandemic. Doctors Koren and Fauci wade through the myriad controversies surrounding the public health response to the COVID-19 pandemic; from its origins, the importance of vaccines, and the balance of public health and individual rights. Finally, the two speak about t ..read more
MedEvidence! Truth Behind the Data
3w ago
Send us a text
Recent guidelines from the Surgeon General indicate that even moderate alcohol consumption poses significant health risks, particularly increasing the likelihood of several cancers. In this episode, cardiologist Dr. Michael Koren and GI specialist Dr. Bharat Misra analyze the data on alcohol and if it aligns with the Surgeon General's recommendation to add warning labels to alcohol.
The doctors suggest limiting the number of days per week alcohol is consumed and challenge traditional views to look at effects on cancers, heart health, and social aspects. They emphasize the ..read more
MedEvidence! Truth Behind the Data
3w ago
Send us a text
On this week's Monday Morning Minute, Dr. Michael Koren and Kevin Geddings discuss the worry uncertainty brings in a changing government landscape and how this affects healthcare. They discuss the stress of not knowing what to expect with competing visions from the incoming administration and how the structure of clinical research trials provides consistency in uncertain times. The two talk about what may change with the second Trump administration, including research funding, healthcare dollars, and access to medicines like the GLP-1 inhibitors Maunjaro and Ozempic that help wi ..read more
MedEvidence! Truth Behind the Data
3w ago
Send us a text
Dr. Michael Koren sits down with Alexandria Clark and Anna Fehr of One of a Kind (1-OAK) Clinical Research to discuss their bold decision to launch a clinical research company in 2021, shortly after the disruptions caused by the COVID-19 pandemic. Dr. Koren reflects on how the pandemic reshaped the clinical research landscape, forcing the closure of many smaller sites which couldn't continue seeing patients in-person. Alexandria and Anna saw an opportunity in the vacuum to build a business specializing in high-need areas like asthma, immunology, and gastroenterology. The convers ..read more