By Vince Giuliano 9-27 -2023 Preface and a personal note In April of this year, I experienced a breakthrough in understanding human aging.  This was a key event for me, coming after 15 years of full-time study and writing 600 or so articles on nearly every conceivable facet of the subject.  A second key breakthrough was directly derived from this understanding.  I had finally articulated a simple set of interventions, applicable late in life, that can likely extend healthy active human lifespans by 20% to 30%, allowing most people to be healthy and continuing contributors to the ..read more

By Vince Giuliano 5-31-2023 Since reading Arthur C. Clark’s Childhood End in 1953, I have been on the lookout for signs of the next step of Human Evolution.  As described in the Wikipedia article on the book “the time of humanity as a race composed of single individuals with a concrete identity is coming to an end. The children’s minds reach into each other and merge into a single vast group consciousness.    If the Pacific were to be dried up, the islands dotting it would lose their identity as islands and become part of a new continent; in the same way, the children cease t ..read more

By Vince Giuliano The causal chain of events leading to advanced human aging has only been clarified very recently.  A key step in this causal chain is systemic inflammation leading to accelerated epigenetic aging.  In reports of other researcher and in our own findings, It has become increasingly clear that aging can be slowed down considerably.  One easy way this is achievable is by pursuing a simple life extension program that features reducing such inflammation through taking certain herbal dietary supplements.  Thus, before much longer many of us might be li ..read more

Zoom Link: April 5, 2023, @ 7pm Pacific Time https://us02web.zoom.us/j/81643696466?pwd=bk1ZVll6SEw5dUkzZzdmcDZPSUpydz09 Evidence and insight from several recent longevity science studies constitute a turning point for Longevity Science Enthusiasts. We now know that Aging Factors Exist in our Blood Plasma. And we know there are ways to reduce/dilute these factors, and by doing so increase health and survival probability There are several Interventions we can do now to reduce/dilute these factors. Some of these interventions are new, others are ancient. If done optimally in an informed wa ..read more

By A. Christopher Wikman Preface by Vince Giuliano I see this article by Christ Wikman as highly relevant for anybody who wants to understand their own health or enhance their longevity. Historically, fundlemental scientific discoveries and technologies have been based on new instruments that allow us to observe phenomena that we had no clue existed because they are are unperceivable to our native senses.  In astronomy, the telescope, and new space telescopes like the Hubble and Web led us to radical new understanding the universe in which we exist.  In physics, generations of atom s ..read more

By Vince Giuliano There are two distinct faces of life extension which are often confused, even by the best researchers working in the longevity field.  This sometimes leads to paradoxical observations.  I seek to clarify what these faces are in this blog entry, present evidence for the distinction between them, state how and why both are important, and relate them to longevity interventions previously discussed in this blog.     Two categories of processes and interventions exist that can lead to longer lifespans.  They are very different.  Image source   ..read more

By Vince Giuliano.  With contributions, suggestions and editing by members of the YOUNGING team: Steve Buss, Walter Crompton, Chris Wikman and Debbie Coehlo 5-1-2022 GENERAL CONTEXT From the onset some 12 years ago, this anti-agingfirewalls blog has followed an implicit Mission of contributing to people having and enjoying longer healthy and productive lives.  Some of our posts have been discussions of practical and accessible interventions for doing this, such as taking certain dietary supplement,s or, more recently, exposing ourselves to PEMF interventions.  Other posts ..read more

In the last two months, Vincent and I have given 3 talks about YOUNGING that can now be viewed on YouTube. The first two talks emphasize the two major biological mechanisms central to YOUNGING. In the 3rd talk, we discuss Interventions based in the science of YOUNGING. Two Talks at Oregon State University (OSU) We were invited by Dr. Deborah Coehlo to give two March 2022 lectures in her course called Health Psychology. OSU Talk # 1 About YOUNGING via the Cholinergic Anti-Inflammatory Pathway In the first OSU talk, we discussed some important longevity science basics and then reviewed the scie ..read more

By Vince Giuliano and Steve Buss As announced previously, on November 20 2021 Steve Buss and I were featured in an online Meetup of the London Futurist group.  We focused on delivering a coherent presentation of our research reported in a number of our recent YOUNGING-SERIES blogs.  And, on how we believed that this work initiates a new paradigm for aging in all organisms including us, the prospect for reverse aging, and practical YOUNGING interventions.  You can see the vide of the first hour of that meetup presentation on YouTube by clicking HERE.  Further, as extensions ..read more

By Vince Giuliano and Steve Buss  Image source – retinal neuron This is the fifth blog entry on a natural process of aging in reverse we have called YOUNGING 1.0.  It is about a category of practical interventions that humans can use to initiate YOUNGING 1.0 processes in themselves – interventions based on oxygen scarcity in cells, known as hypoxia. The blog entry also identifies a hitherto undiscussed underlying mechanism explaining hypoxic hormesis – a process that involves remarkable health benefits flowing from various temporary conditions of hypoxia in the body, such as wearin ..read more