In this episode Ben Scher talks to Dr Adam Bakker, Professor Michael Liebrenz and Dr Alexander Smith about their commentary in response to a previous paper by Domzaridou and colleages (2023). They discuss the complexities of providing treatment for people who use, and are prescribed, opiates, opiate agonist medications and benzodiazepines. They talk about using a combination of medical and non-medical treatments when working with people who use benzodiazepines as well as the research needed to bring clarity to this pressing clinical issue. "This population is notoriously difficult to engage ..read more

In this episode, Ben Scher talks to Dr Gabriela Khazanov, Professor James McKay and Professor Richard Rawson. They discuss what contingency management is and how effective it can be in treatment settings. They also talk about how contingency management can be used for stimulant use disorders; an area where there are relatively few evidence-based treatments. the team goes on to discuss implementation of contingency management in the US and the barriers faced by practitioners such as predominant ethical concerns. They also cover how attitudes towards contingency management have changed over the ..read more

In this episode Ben Scher talks to Dr Caroline Copeland about her work analysing drug death data to identify drug use trends, harms and to inform policy. Caroline talks about how xylazine first entered the US drug market but has been increasingly identified in Europe and the UK, even being identified in vapes sold as containing tetrahydrocannabinol (THC). Caroline covers the harms from xylazine and the implications for public health practitioners before relating the UK issues to wider global drug markets. "The other really nasty thing that xylazine does is that it can cause blood vessels to c ..read more

In this episode, Dr Elle Wadsworth talks to Paul Griffiths about synthetic drug production in Europe including the differences between lab-made substances and diverted medical drugs. They discuss organised crime and its impact on cocaine production, drug availability and the potential for drug contamination. They also cover fentanyl and the potential for a heroin drought resulting from changes in opium production in Afghanistan. Paul talks about the complexities of European drug markets explaining how they commonly respond to changes in both supply and demand. Elle and Paul then discuss how r ..read more

In this episode Dr Merve Mollaahmetoglu talks to Dr Molly Bowdring about her recent article on the impact of alcohol-free drinks such as zero-percent beers, wines and mocktails. Molly talks about using survey data to explore different patterns, such as using non-alcoholic drinks to slow alcohol consumption, to alternate days or as part of someones recovery. Merve and Molly discuss the occasional differences between how people think non-alcoholic drinks change their alcohol consumption and what actually happens to their overall use. If you're somebody who already uses them, be reflective about ..read more

In this episode, Rob Calder talks to Dr Philip Newall about how the gambling industry frames the evidence on gambling advertising. Philip talks about researching the kinds of bets that are commonly advertised, explaining how they are often projected to be 'good' bets when the chances of winning are very small. "It's really got the two sides of the coin there in that it appears really attractive, but actually it's the bookmaker that's really winning the most. And that's the underlying psychology in how they're able to offer things that seem good but are actually really profitable for them." P ..read more

In this episode Dr Elle Wadsworth talks to Sammie Back and Emese Kroon about nitrous oxide. The discussion happened on 8 November 2023, on the day that possession of nitrous oxide became a Class C substance in the UK. The group discuss the existing evidence for harms, addiction and other disorders, exploring this relatively under-researched area. They cover the lack of research and how researchers can begin to understand what's happening when a drug's popularity rapidly increases. They also talk about how people use nitrous oxide and in which circumstances use might be more likely. Finally, t ..read more

In this episode Rob Calder talks to Francesco Manca about his research on Scotland's Minimum Unit Pricing (MUP) policy for alcohol, and specifically about the impact that MUP has had on road traffic accidents. Francesco discusses how the research team selected appropriate comparitors to assess whether changes to road traffic accidents could be attributed to MUP. He also talks about how this study compares with previous studies that used similar datasets yet drew different conclusions. He describes how understanding the subtle differences between time frames and outcomes can aid researchers to ..read more

In this episode, Zoe Swithenbank talks to Drs Amy O'Donnell and Kat Jackson about their recent study on how to improve care for people with coexisting heavy drinking and depression. The discuss the theoretical concept of Relational Autonomy and how it influenced their research. Amy and Kat describe how they set up the research, and in particular the challenges of recruiting participants from groups where your research is not their priority. They also talk about how much work it takes to conduct effective PPI (Patient and Public Involvement) and how important it is to do it well. They then go ..read more

In this episode, Rob Calder talks to Zoe Swithenbank about her recent article looking at how to improve research reports on smoking cessation trials. Zoe talks about the challenges of organising an international meeting of experts before the COVID-19 pandemic (before people were used to online working). She talks about some common errors and omissions that researchers make when reporting smoking cessation trials and how these can place limits on scientific progress. She talks about developing the CONSORT-SPI tool to help improve the ability of researchers to draw conclusions across studies ..read more