The New England Journal of Medicine
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The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles and editorial opinions on a wide variety of topics of importance to biomedical science and clinical practice.
The New England Journal of Medicine
3d ago
Air Pollution, Mortality, Race, and Social Class In this large study, the mortality benefits of reducing levels of fine particulate matter air pollution were greater for low-income and higher-income Black persons and for low-income White persons than for higher-income White persons ..read more
The New England Journal of Medicine
2w ago
Inaxaplin in Persons with Two In a phase 2a study, 16 participants with nephropathy received inaxaplin, an inhibitor of APOL1 channel function. Among 13 evaluable participants, the mean reduction in proteinuria was 47.6% at week 13 ..read more
The New England Journal of Medicine
3w ago
Transcatheter repair of secondary mitral regurgitation was associated with a lower rate of hospitalization for heart failure and lower all-cause mortality than medical therapy at 5 years of follow-up ..read more
The New England Journal of Medicine
1M ago
Focused Ultrasound Ablation for Parkinson’s Disease In patients with Parkinson’s disease, focused ultrasound ablation of the globus pallidus internus reduced motor impairment and dyskinesias at 3 months. Adverse events included dysarthria, gait disturbance, and loss of taste ..read more
The New England Journal of Medicine
1M ago
In a trial conducted in China, patients with large cerebral infarctions as determined by imaging criteria within 24 hours after onset had better outcomes with endovascular therapy than with medical therapy alone ..read more
The New England Journal of Medicine
1M ago
In patients with treatment-resistant hypertension and blood pressure of 130/80 mm Hg or higher, the aldosterone synthase inhibitor baxdrostat reduced blood pressure in a dose-related manner ..read more
The New England Journal of Medicine
2M ago
Initial treatment of paroxysmal atrial fibrillation with cryoballoon ablation was associated with a lower incidence of persistent atrial fibrillation and other atrial tachyarrhythmias over 3 years than rhythm-control medications ..read more
The New England Journal of Medicine
2M ago
Monoclonal Antibody for Early Alzheimer’s Disease In a phase 3 trial, participants with early Alzheimer’s disease who received the monoclonal antibody lecanemab had less decline on measures of cognition and function at 18 months than those who received placebo ..read more
The New England Journal of Medicine
3M ago
In this trial, a 24-week regimen of bedaquiline, pretomanid, linezolid, and moxifloxacin was noninferior to standard care for rifampin-resistant tuberculosis ..read more
The New England Journal of Medicine
3M ago
Implications of the 2022 Election for Health Policy The rapid identification of a correlate of protection for Covid-19 vaccines — on the basis of several harmonized randomized phase 3 trials using common validated assays — constitutes an important success in vaccinology ..read more