Chemistry, Vol. 5, Pages 1407-1418: Suzuki–Miyaura Reaction in the Presence of N-Acetylcysteamine Thioesters Enables Rapid Synthesis of Biomimetic Polyketide Thioester Surrogates for Biosynthetic Studies Chemistry doi: 10.3390/chemistry5020096 Authors: Sebastian Derra Luca Schlotte Frank Hahn Biomimetic N-acetylcysteamine thioesters are essential for the study of polyketide synthases, non-ribosomal peptide synthetases and fatty acid synthases. The chemistry for their preparation is, however, limited by their specific functionalization and their susceptibility to undesired side reacti ..read more

Chemistry, Vol. 5, Pages 1329-1343: Using Imidazolium in the Construction of Hybrid 2D and 3D Lead Bromide Pseudoperovskites Chemistry doi: 10.3390/chemistry5020090 Authors: Gonzalo García-Espejo Konstantis F. Konidaris Antonietta Guagliardi Norberto Masciocchi The field of hybrid organic–inorganic perovskite materials continues to attract the interest of the scientific community due to their fascinating properties and the plethora of promising applications in photovoltaic and optoelectronic devices. To enhance the efficiency and stability of perovskite-based devices, it is essen ..read more

Chemistry, Vol. 5, Pages 1317-1328: Multiple Intramolecular Hydrogen Bonding in Large Biomolecules: DFT Calculations and Deuterium Isotope Effects on 13C Chemical Shifts as a Tool in Structural Studies Chemistry doi: 10.3390/chemistry5020089 Authors: Poul Erik Hansen Fadhil S. Kamounah Large biomolecules often have multiple intramolecular hydrogen bonds. In the cases where these interact, it requires special tools to disentangle the patterns. Such a tool could be deuterium isotope effects on chemical shifts. The use of theoretical calculations is an indispensable tool in such studies. The pres ..read more

Chemistry, Vol. 5, Pages 1271-1287: Improved Synthesis and Coordination Behavior of 1H-1,2,3-Triazole-4,5-dithiolates (tazdt2−) with NiII, PdII, PtII and CoIII Chemistry doi: 10.3390/chemistry5020086 Authors: Nils Pardemann Alexander Villinger Wolfram W. Seidel A new synthetic route to 1H-1,2,3-triazole-4,5-dithiols (tazdtH2) as ligands for the coordination of NiII, PdII, PtII and CoIII via the dithiolate unit is presented. Different N-protective groups were introduced with the corresponding azide via a click-like copper-catalyzed azide-alkyne [3 + 2] cycloaddition (CuAAC) and fully ..read more