This podcast the dependence of the brain on glucose as an energy source. Although the brain can use ketone bodies, it only does that in prolonged fasts. Instead the brain can instruct other organs to release hormones that will restore blood glucose ..read more

This pocast covers the endocrine pancreas and the role of the beta cells in secretion of insulin. The rise in bloodstream glucose triggers the increase of glucose uptake by the pancreas by glut-2 transporter, followed by an increase in glycolysiss and a rise in ATP in the cytoplasm. This rise triggers a cascade of events inside the beta cells leading to insulin release ..read more

This podcast covers the tissue distribution of various glucose transporters and their role of glucose uptake from the bloodstream, including the regulation of one transporter (Glut-4) by insulin ..read more

This podcast covers the major glucose transporters, their tissue distribution, and regulation by hormones. The key role of these transporters is to pick up glucose from the bloodstream so it can be further metabolized by the cell. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message ..read more

This podcast covers 4 distinct classes of receptors and their respective hormones, including the mechanism of transducing their intracellular signals. The receptors covered in detail are the steroid receptor, the insulin receptor, and 3 distinct G-protein coupled receptors, including the second messengers they produce. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message ..read more

This podcast covers the use of glucose and ketone bodies as energy sources by the brain. During sleep and short fasts, the brain is completely dependent on the output of glucose by the liver. Glucose is oxidized all the way to CO2 by the brain under aerobic conditions to produce up to 38ATPs. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message ..read more

This podcast covers the tissue distribution of various glucose transporters and their role of glucose uptake from the bloodstream, including the regulation of one transporter (Glut-4) by insulin. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message ..read more

This podcast covers the salvage of Hypoxanthine, guanine and adenine by two important enzymes Hypoxanthine-guanine phosphoribosyl transferase (HGPRT) and Adeneine phosphoribosyl transferase (APRT), including the outcome of an inherited deficiency in HGPRT. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message ..read more

This podcast covers the insulin-dependent uptake of glucose by GLUT-4 in muscle and adipose tissue. This insulin-dependent uptake by these tissues contributes to the reduction of plasma glucose after a meal. Check out the link below for the video podcast: https://youtu.be/_vyijJKL4oY --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message ..read more

This podcast covers the essential role of glucose as an energy source for several tissues. Most notably, red blood cells and the brain. Red blood cells are entirely dependent on glucose for their energy needs while the brain is highly dependent on glucose for its energy. Glucose in the bloodstream is produced by the liver and maintained around 80-100mg/dl during fasting to provide red blood cells and the brain with their energy needs. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message ..read more