Hormonal Regulation of Metabolism in a Nutshell
Metabolism Made Easy
by A J Ghalayini, Ph.D.
3w ago
This podcast covers 4 distinct classes of receptors and their respective hormones, including the mechanism of transducing their intracellular signals. The receptors covered in detail are the steroid receptor, the insulin receptor, and 3 distinct G-protein coupled receptors, including the second messengers they produce. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message ..read more
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The Brain's Energy Sources
Metabolism Made Easy
by A J Ghalayini, Ph.D.
1M ago
This podcast covers the use of glucose and ketone bodies as energy sources by the brain. During sleep and short fasts, the brain is completely dependent on the output of glucose by the liver. Glucose is oxidized all the way to CO2 by the brain under aerobic conditions to produce up to 38ATPs. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message ..read more
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GLucose Transporters
Metabolism Made Easy
by A J Ghalayini, Ph.D.
1M ago
This podcast covers the tissue distribution of various glucose transporters and their role of glucose uptake from the bloodstream, including the regulation of one transporter (Glut-4) by insulin. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message ..read more
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The Purine Salvage Pathway
Metabolism Made Easy
by A J Ghalayini, Ph.D.
1M ago
This podcast covers the salvage of Hypoxanthine, guanine and adenine by two important enzymes Hypoxanthine-guanine phosphoribosyl transferase (HGPRT) and Adeneine phosphoribosyl transferase (APRT), including the outcome of an inherited deficiency in HGPRT. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message ..read more
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Glucose Uptake by Muscle & Adipose Tissue
Metabolism Made Easy
by A J Ghalayini, Ph.D.
2M ago
This podcast covers the insulin-dependent uptake of glucose by GLUT-4 in muscle and adipose tissue. This insulin-dependent uptake by these tissues contributes to the reduction of plasma glucose after a meal. Check out the link below for the video podcast: https://youtu.be/_vyijJKL4oY --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message ..read more
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Glucose: The Essential Nutrient
Metabolism Made Easy
by A J Ghalayini, Ph.D.
2M ago
This podcast covers the essential role of glucose as an energy source for several tissues. Most notably, red blood cells and the brain. Red blood cells are entirely dependent on glucose for their energy needs while the brain is highly dependent on glucose for its energy. Glucose in the bloodstream is produced by the liver and maintained around 80-100mg/dl during fasting to provide red blood cells and the brain with their energy needs. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message ..read more
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Hormones & Receptors: 4 Distinct Types
Metabolism Made Easy
by A J Ghalayini, Ph.D.
2M ago
This podcast covers the four different classes of receptors that illicit intracellular signals, including steroid receptors, ion channel receptors, receptor enzymes, and G-protein coupled receptors. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message ..read more
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Insulin Effects on Carbohydrate & Lipid metabolism
Metabolism Made Easy
by A J Ghalayini, Ph.D.
3M ago
This episode summarizes the key effects on carbohydrate and lipid metabolism, including the processes that are activated by insulin and the ones inhibited by it. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message ..read more
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Enzyme Inhibition
Metabolism Made Easy
by A J Ghalayini, Ph.D.
3M ago
This podcast describes 4 distinct types of enzyme inhibitors and their mechanism of inhibition, including: substrate analogues, toxins, allosteric inhibitors, and heavy metals. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message ..read more
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Glycolysis: Regulation of Pyruvate Kinase
Metabolism Made Easy
by A J Ghalayini, Ph.D.
4M ago
This podcast covers the regulation of pyruvate kinase allosterically and by hormone-dependent (insulin & glucagon) covalent modification. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message ..read more
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