ITRAQ-based proteomic study on monocyte cell model discovered an association of LAMP2 downregulation with HIV-1 latency
BMC| Proteome Science
by Lin Yin, Qimin Wang, Siyuan Liu, Jun Chen, Yujiao Zhang, Lingqing Lu, Hongzhou Lu, Zhigang Song and Lijun Zhang
4M ago
Patients with immunodeficiency virus-1 (HIV-1) infection are challenging to be cured completely due to the existence of HIV-1 latency reservoirs. However, the knowledge of the mechanisms and biomarkers associate ..read more
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A methodological exploration of distinguishing hair quality based on hair proteomics
BMC| Proteome Science
by Xiaolin Wu, Tao Zhang, Mingsong Mao, Yali Zhang, Zhenpeng Zhang and Ping Xu
4M ago
Hair is an advantageous biological sample due to its recordable, collectable, and storable nature. Hair's primary components are keratin and keratin-associated proteins. Owing to its abundance of cystine, kera ..read more
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Exosome proteomes reveal glycolysis-related enzyme enrichment in primary canine mammary gland tumor compared to metastases
BMC| Proteome Science
by Hui-Su Kim and Je-Yoel Cho
7M ago
Numerous evidence has highlighted the differences between primary tumors and metastases. Nonetheless, the differences in exosomal proteins derived from primary tumor and metastases remain elusive. Here, we aim ..read more
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Comparative proteomics reveals different protein expression in platelets in patients with alcoholic liver cirrhosis
BMC| Proteome Science
by Nima Haji Begli, Cora Freund, Karl-Heinz Weiss, Daniel Gotthardt and Andreas Wannhoff
8M ago
The role of platelets in disease progression as well as the function of platelets as part of the haemostatic and immunological system in patients with liver cirrhosis is only incompletely understood. This is p ..read more
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Methionine enkephalin (MENK) protected macrophages from ferroptosis by downregulating HMOX1 and ferritin
BMC| Proteome Science
by Jing Tian, Wenrui Fu, Zifeng Xie, Yuanlong Zhao, Haochen Yang and Jiafan Zhao
8M ago
The aim of this work was to investigate the immunological effect of MENK by analyzing the protein spectrum and bioinformatics of macrophage RAW264.7, and to explore the relationship between macrophage and ferr ..read more
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Proteomic profile of tepary bean seed storage proteins in germination with low water potential
BMC| Proteome Science
by Daniel Padilla-Chacón, Laura Campos-Patiño, Cecilia B. Peña-Valdivia, Antonio García-Esteva, José Cruz Jiménez-Galindo and Jorge Luis Pizeno-García
9M ago
Tepary bean (Phaseolus acutifolius A. Gray) is one of the five species domesticated from the genus Phaseolus with genetic resistance to biotic and abiotic stress. To understand the mechanisms underlying drought r ..read more
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Upregulation of S100A8 in peripheral blood mononuclear cells from patients with depression treated with SSRIs: a pilot study
BMC| Proteome Science
by Concepción Gamboa-Sánchez, Enrique Becerril-Villanueva, Samantha Alvarez-Herrera, Gabriela Leyva-Mascareño, Sandra L. González-López, Enrique Estudillo, Alberto E. Fernández-Molina, José Miguel Elizalde-Contreras, Eliel Ruiz-May, Aldo Segura-Cabrera, Janeth Jiménez-Genchi, Lenin Pavón, Sergio Roberto Zamudio and Gilberto Pérez-Sánchez
10M ago
Major depressive disorder (MDD) affects more than 350 million people worldwide, and there is currently no laboratory test to diagnose it. This pilot study aimed to identify potential biomarkers in peripheral b ..read more
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Systematic proteomics profiling of lysine crotonylation of the lung at Pseudoglandular and Canalicular phases in human fetus
BMC| Proteome Science
by Wei Wang, Wei Shi, Yinglan Wang, Yane Yang, Ping Li, Zhipeng Zeng, Wenlong Hu, Yumei Chen, Donge Tang and Yong Dai
10M ago
Lung tissue is an important organ of the fetus, and genomic research on its development has improved our understanding of the biology of this tissue. However, the proteomic research of developing fetal lung ti ..read more
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TMT quantitative proteomics reveals key proteins relevant to microRNA-1-mediated regulation in osteoarthritis
BMC| Proteome Science
by Pinpin Jiang, Dan Liang, Hang Wang, Raorao Zhou, Xianda Che, Linlin Cong, Penghua Li, Chunfang Wang, Wenjin Li, Xiaochun Wei and Pengcui Li
10M ago
Osteoarthritis (OA) is the second-commonest arthritis, but pathogenic and regulatory mechanisms underlying OA remain incompletely understood. Here, we aimed to identify the mechanisms associated with microRNA ..read more
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Label-free quantitative proteomic analysis of serum exosomes in mice with thoracic aortic aneurysm
BMC| Proteome Science
by Jia Xu, Jiacheng Liu, Yibai Qu, Linhui Jiang, Rongxin Liang, Bohai Li, Lei Li and Yong Jiang
11M ago
Thoracic aortic aneurysm (TAA) is a cardiovascular disease with high morbidity and mortality. However, the causes and mechanisms of TAA are not fully understood. Serum exosomes from mice with TAA were used to ..read more
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