Alkalinization Using Sodium Bicarbonate for COVID-19 Treatment: A Systematic Review and Meta-Analysis
SAGE Journals » Journal of Evidence-Based Integrative Medicine
by Arman Shafiee, Kyana Jafarabady, Hassan Moltazemi, Mohammad Javad Amini, Mohammad Ali Rafiei, Amirhossein Akhondi, Sayed-Hamidreza Mozhgani
2w ago
Journal of Evidence-Based Integrative Medicine, Volume 29, Issue , January-December 2024. BackgroundA systematic review and meta-analysis have been conducted to evaluate the efficacy of alkalinization for COVID-19 patients based on current evidence to determine the impact of alkalinization on COVID-19 outcomes.MethodsWe searched MEDLINE (Pubmed), Web of Science, Cochrane Library, and Clinicaltrials.gov for studies evaluating the efficacy of alkalinization up to 30 April 2023. Based on the PRISMA 2020 statement criteria a systematic review and meta-analysis of studies were performed.ResultsThe ..read more
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A Combination of Curcumin and Lactobacillus rhamnosus GG Inhibits Viability and Induces Apoptosis in SCC-9 Human Oral Squamous Cell Carcinoma Cells
SAGE Journals » Journal of Evidence-Based Integrative Medicine
by Chatchaphan Udompatanakorn, Panan Ratthawongjirakul
3w ago
Journal of Evidence-Based Integrative Medicine, Volume 29, Issue , January-December 2024. The aim of this study was to evaluate the effect of curcumin combined with Lactobacillus rhamnosus GG cell-free supernatant (LGG CFS) on the proliferation and induction of apoptosis in SCC-9 oral squamous cell carcinoma (OSCC) cells. Curcumin (40 µg/ml) and 25% v/v LGG CFS (108 CFU/ml), both alone and in a combination regimen, significantly decreased the viability of SCC-9 cells and normal human gingival fibroblast (HGF) cells. Interestingly, the combination of low doses of curcumin (5 µg/ml) and 25% v/v ..read more
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In Vivo Anti-Hepatocellular Carcinoma Effects of the Chloroform Root Extract of Clausena excavata Burm
SAGE Journals » Journal of Evidence-Based Integrative Medicine
by Peter Waziri, Richard Auta, Mustapha U Imam, Ben A Chindo, Zakari Ladan, Zainab Mohammed, Samson Wayah, Ja'afar Mohammed, Mohammed I Tahir, Abdurrahman E Ahmad, Yusuf Alhassan, Daniel Tyoapine, Abel S Agbaji
1M ago
Journal of Evidence-Based Integrative Medicine, Volume 29, Issue , January-December 2024. Liver cancer is the most common cancer among males in Africa. The disease has a poor prognosis and its treatment is associated with toxicity and resistance. For this reason, numerous herbal combinations are being subjected to anticancer screening to circumvent the shortcomings of the conventional anticancer drugs. In the current study, the in vivo anti-cancer effects of the chloroform root extract of the herb, Clausena excavata Burm were investigated. Liver cancer was induced in mice by a single intraperi ..read more
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Effect of Aqueous Extract of Unripe Musa Paradisiaca Linn on Parameters Affecting Reproduction in Rats
SAGE Journals » Journal of Evidence-Based Integrative Medicine
by Collins Azubuike Onyeto, Akachukwu Marytheresa Onwuka, Ikechukwu Emmanuel Peter, Chukwuemeka Sylvester Nworu, Peter Achunike Akah
1M ago
Journal of Evidence-Based Integrative Medicine, Volume 29, Issue , January-December 2024. ObjectiveAqueous extract of unripe Musa paradisiaca fruit is commonly used for the treatment of ulcers in eastern Nigeria. This study aimed to assess the acute and subacute effects of an aqueous extract of unripe fruit on male and female fertility in rats.MethodsAqueous extracts obtained by maceration were analyzed for acute and subacute toxicity and for the presence of phytochemical constituents using standard procedures. The extract (100, 500, and 1000 mg/kg) was administered daily to rats of both sexes ..read more
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Garcinia dulcis Extract Alleviates Inflammation in Kidney and Liver of the 2-Kidney-1-Clip Hypertensive rat
SAGE Journals » Journal of Evidence-Based Integrative Medicine
by Nattaya Thongsepee, Wanwisa Himakhun, Ratsikan Parachat, Pongsakorn Martviset, Pathanin Chantree, Phornphan Sornchuer, Kant Sangpairoj, Siriphun Hiranyachattada
2M ago
Journal of Evidence-Based Integrative Medicine, Volume 29, Issue , January-December 2024. Garcinia dulcis (GD) extract possesses anti-hypertensive property that are poorly characterized. This study aimed to investigate an anti-inflammatory effect of GD flower extract in the 2-kidney-1-clip (2K1C) hypertensive compared to sham operative (SO) rat. Male Wistar rats were divided into 2 groups; the 2K1C group in which a silver clip was placed around renal artery to induce hypertension, and the SO normotensive group. Four weeks later, each group of rats were further divided into 2 subgroups, each su ..read more
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Objective Evaluation of Pulse Width Using an Array Pulse Diagram
SAGE Journals » Journal of Evidence-Based Integrative Medicine
by Zi-Juan Bi, Ji Cui, Xing-Hua Yao, Xiao-Juan Hu, Si-Han Wang, Meng-Chen Liang, Zhi-Hui Zhou, Jia-Tuo Xu
2M ago
Journal of Evidence-Based Integrative Medicine, Volume 29, Issue , January-December 2024. BackgroundPulse width, which can reflect qi, blood excess, and deficiency, has been used for diagnosing diseases and determining the prognosis in traditional Chinese medicine (TCM). This study aimed to devise an objective method to measure the pulse width based on an array pulse diagram for objective diagnosis.MethodsThe channel 6, the region wherein the pulse wave signal is the strongest, is located in the middle of the pulse sensor array and at the guan position of cunkou during data collection. Therefo ..read more
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Cognition Enhancing Potential of Aqueous Leaf Extract of Amaranthus dubius in Mice
SAGE Journals » Journal of Evidence-Based Integrative Medicine
by Daisy Jepkosgei Kipkemoi, Anthony Murithi Ireri, Mathew Piero Ngugi
7M ago
Journal of Evidence-Based Integrative Medicine, Volume 28, Issue , January-December 2023. Amaranthus dubius is a vegetable consumed for its nutritional content in Kenya. In herbal medicine, A. dubius is utilized to relief fever, anemia and hemorrhage. Additionally, it is utilized to manage cognitive dysfunction and is considered to augment brain function, but there is no empirical evidence to support this claim. The contemporary study investigated cognitive enhancing potential of A. dubius in mice model of Alzheimer's disease (AD)-like dementia induced with ketamine. Cognitively damaged mice w ..read more
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Comparing Vitamin D Level Between Patients with Psoriasis and Healthy Individuals: A Systematic Review and Meta-Analysis
SAGE Journals » Journal of Evidence-Based Integrative Medicine
by Mahmood Moosazadeh, Giovanni Damiani, Mohammad Khademloo, Motahareh Kheradmand, Fatemeh Nabinezhad-Male, Amirhossein Hessami
7M ago
Journal of Evidence-Based Integrative Medicine, Volume 28, Issue , January-December 2023. BackgroundPsoriasis is nowadays regarded as a systemic inflammatory disorder. Among the topicals, vitamin D derivates are often applied on the skin for their anti-inflammatory and immune-modulatory properties. Vitamin D serum levels in psoriasis (PsO) patients are still debated and an eventual depletion may offer the rational to integrate anti-psoriatic therapies with oral vitamin D. Then, we aimed to perform a systematic review and meta-analysis on the current evidence towards serum vitamin D level in Ps ..read more
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Cassava (Manihot esculenta Crantz): A Systematic Review for the Pharmacological Activities, Traditional Uses, Nutritional Values, and Phytochemistry
SAGE Journals » Journal of Evidence-Based Integrative Medicine
by Siti Raudhah Noor Shifa Putri Mohidin, Said Moshawih, Andi Hermansyah, Mohd Ikmal Asmuni, Naeem Shafqat, Long Chiau Ming
8M ago
Journal of Evidence-Based Integrative Medicine, Volume 28, Issue , January-December 2023. Cassava (Manihot esculenta Crantz) is considered one of the essential tuber crops, serving as a dietary staple food for various populations. This systematic review provides a comprehensive summary of the nutritional and therapeutic properties of cassava, which is an important dietary staple and traditional medicine. The review aims to evaluate and summarize the phytochemical components of cassava and their association with pharmacological activities, traditional uses, and nutritional importance in global ..read more
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A Short-Term Safety Evaluation of Silbinol®- an Extract from Pterocarpus marsupium in Healthy Adults- a Randomized, Double-Blind, Placebo-Controlled Study
SAGE Journals » Journal of Evidence-Based Integrative Medicine
by Muhammed Majeed, Kalyanam Nagabhushanam, Shaji Paulose, Lakshmi Mundkur
10M ago
Journal of Evidence-Based Integrative Medicine, Volume 28, Issue , January-December 2023. Background: Pterostilbene is an active molecule from the bark of the Pterocarpus marsupium tree with antioxidant and anti-inflammatory properties. Objective: This study aimed to evaluate the clinical safety of a standardized P. marsupium extract (PME) containing 90% pterostilbene (200 mg per day) in healthy adults. Methods: In a randomized, double-blind, placebo-controlled study, 60 healthy adult participants (27 males and 33 females) were randomized to receive PME-100 mg or placebo capsule twice a day fo ..read more
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