Naila brings you 21 articles from January 2024, on non-pharmacological approaches to the prevention and intervention of Alzheimer's disease. You'll be treated to research from computational modeling, to rodent models, to clinical trials, with a particular focus on optimizing and personalizing intervention strategies. This episode also covers some research on the role of caregivers, and several papers consider the socioeconomic and ethnographic context in which these studies take place. Let's get to it!   Stimulation Techniques (7) Exercise (3) Cognitive Training (2)   Art Therapy and ..read more

Join Christy for 12 papers from January 2024 on structural neuroimaging in the diagnosis of Alzheimer's disease. This episode is a bit different from past ones because it's all about the use of machine learning and deep learning. Whether you're an AI researcher or simply curious about the topic, you won't want to miss this episode.   Detecting AD (3:42)   Predictions, associations or comparisons (16:48) --------------------------------------------------------------  You can find the bibliography for this episode here, or by clicking the link below: https://drive.google.com/file ..read more

Another series of AMiNDR kicks off with this episode. Anusha takes you through 7 papers published in January 2024 targeting neuroprotection in AD. If you'd like to hear about potential compounds that could reduce neurodegeneration in Alzheimer's disease, this is the episode for you. Testing for neuroprotection in cell lines (2:57) Testing for neuroprotection using in vivo AD models (11:47) --------------------------------------------------------------  You can find the bibliography for this episode here, or by clicking the link below: https://drive.google.com/file/d/1A4HZVCtgh5AwZkd5V2ATZ ..read more

Another special episode to help kick off our return! In what we hope to be a recurring special series, an interview with members in our scholarly community on navigating the multiple facets of life as a scientist. In the first episode, host Kevin Nishimura interviews one of our own Joseph Liang on his personal journey to and through graduate school. Tune in to learn what he has to say about getting into graduate school, and how his perspective on the journey has changed since he's started! We hope you enjoy, and please let us know if you want to hear more episodes like this!   To access t ..read more

In today's episode, Naila provides an overview of 14 articles published in November 2023 on non-pharmacological interventions for AD. You'll hear about cognitive training, music therapy, chair yoga, providing support to caregivers, and a range of neural stimulation techniques. Enjoy!   Cognitive and Social Factors (2:26) Lifestyle interventions (13:40) Stimulation Techniques (19:20) --------------------------------------------------------------  You can find the bibliography for this episode here, or by clicking the link below: https://drive.google.com/file/d/1A4HZVCtgh5AwZkd5V2ATZSF ..read more

Join us as we cover a set of papers published in November 2023 on treatments targeting cholinergic transmission in Alzheimer's disease. In this episode hosted by Christy, we will go over various topics, from drug discovery using synthesized compounds to drug testing of plant extracts, as well as improving drug delivery through the blood-brain barrier. Enjoy!   Papers evaluating synthesized compounds (2:00)   Papers targeting AchE (10:45) --------------------------------------------------------------  You can find the bibliography for this episode here, or by clicking the link be ..read more

As we get back up to speed on our regular episodes, we thought we'd treat you (and ourselves) to something out of the ordinary: a conversation on how visual storytelling can shape how we think - and feel - about Alzheimer's disease. Host Naila Kuhlmann had the pleasure of interviewing Gina Martin, who founded the Bob and Diane Fund to support and promote visual storytelling about Alzheimer's and dementia. Tune in to get the backstory on the fund, an auditory glimpse at the work of this year's winner, a discussion on the social narrative of Alzheimer's disease, and reflections on the role of th ..read more

In today's episode, Naila provides you with an overview of 10 paper published in February 2023, on non-pharmacological therapies for Alzheimer's disease. You'll learn about a virtual reality intervention targeting anxiety, the signaling pathways underlying the potential benefits of acupuncture, the challenges of implementing new interventions, and what spectral light flicker means. Happy listening!   Sections in this episode:   Psychological Interventions (1:37)   Physical Activity (7:26)   Neuromodulatory Techniques (14:05)  ..read more

Elyn's back with more insight from the field on how blood vessel health impacts brain health. Tune in for a journey through mechanisms underlying increased risk from "vascular risk factors" like hypertension, diabetes, and atrial fibrillation, lots of neuroimaging studies providing clinical insights, and several interesting novel therapeutic avenues. If you weren't already convinced that the vasculature is relevant in the context of AD, you sure will be after this episode!   Sections in this episode:   Cerebral blood flow and hypoperfusion (4:08)   More clinical insights (10:53 ..read more

This episode covers some papers from January 2023 on treatments focused on repairing the neurotransmitter imbalance in Alzheimer's disease. We hope you enjoy listening as Christy summarizes this exciting research—from the discovery of new therapeutics to the synthesis of drugs.   Sections in this episode: Drug Screening (3:37) New Drugs (7:00) Synthesized Drugs (13:35) --------------------------------------------------------------  To find the numbered bibliography with all the papers covered in this episode, click here, or use the link below: https://drive.google.com/file/d/1BkF6ofS ..read more