The relationship between gamma-band neural oscillations and language skills in youth with Autism Spectrum Disorder and their first-degree relatives
BMC » Molecular Autism
by Vardan Arutiunian, Megha Santhosh, Emily Neuhaus, Heather Borland, Chris Tompkins, Raphael A. Bernier, Susan Y. Bookheimer, Mirella Dapretto, Abha R. Gupta, Allison Jack, Shafali Jeste, James C. McPartland, Adam Naples, John D. Van Horn, Kevin A. Pelphrey and Sara Jane Webb
1d ago
Most children with Autism Spectrum Disorder (ASD) have co-occurring language impairments and some of these autism-specific language difficulties are also present in their non-autistic first-degree relatives. O ..read more
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Trajectory of depressive symptoms over adolescence in autistic and neurotypical youth
BMC » Molecular Autism
by Blythe A. Corbett, Rachael A. Muscatello, Trey McGonigle, Simon Vandekar, Christina Burroughs and Sloane Sparks
4d ago
Adolescence coincides with a dramatic rise in the onset of psychiatric conditions including depression. Depression symptoms may be particularly prevalent and impairing for youth with autism spectrum disorder ..read more
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Systematic review and meta-analysis: multimodal functional and anatomical neural alterations in autism spectrum disorder
BMC » Molecular Autism
by Zixuan Guo, Xinyue Tang, Shu Xiao, Hong Yan, Shilin Sun, Zibin Yang, Li Huang, Zhuoming Chen and Ying Wang
3w ago
This meta-analysis aimed to explore the most robust findings across numerous existing resting-state functional imaging and voxel-based morphometry (VBM) studies on the functional and structural brain alteratio ..read more
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Detection of autism spectrum disorder-related pathogenic trio variants by a novel structure-based approach
BMC » Molecular Autism
by Sadhna Rao, Anastasiia Sadybekov, David C. DeWitt, Joanna Lipka, Vsevolod Katritch and Bruce E. Herring
1M ago
Glutamatergic synapse dysfunction is believed to underlie the development of Autism Spectrum Disorder (ASD) and Intellectual Disability (ID) in many individuals. However, identification of genetic markers that ..read more
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Shank3 deficiency elicits autistic-like behaviors by activating p38α in hypothalamic AgRP neurons
BMC » Molecular Autism
by Shanshan Wu, Jing Wang, Zicheng Zhang, Xinchen Jin, Yang Xu, Youwen Si, Yixiao Liang, Yueping Ge, Huidong Zhan, Li peng, Wenkai Bi, Dandan Luo, Mengzhu Li, Bo Meng, Qingbo Guan, Jiajun Zhao…
1M ago
SH3 and multiple ankyrin repeat domains protein 3 (SHANK3) monogenic mutations or deficiency leads to excessive stereotypic behavior and impaired sociability, which frequently occur in autism cases. To date, t ..read more
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Neuroligin-2 shapes individual slow waves during slow-wave sleep and the response to sleep deprivation in mice
BMC » Molecular Autism
by Tanya Leduc, Hiba El Alami, Khadija Bougadir, Erika Bélanger-Nelson and Valérie Mongrain
1M ago
Sleep disturbances are a common comorbidity to most neurodevelopmental disorders and tend to worsen disease symptomatology. It is thus crucial to understand mechanisms underlying sleep disturbances to improve ..read more
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Clinical correlates of diagnostic certainty in children and youths with Autistic Disorder
BMC » Molecular Autism
by Eya-Mist Rødgaard, Borja Rodríguez-Herreros, Abderrahim Zeribi, Kristian Jensen, Valérie Courchesne, Elise Douard, David Gagnon, Guillaume Huguet, Sebastien Jacquemont and Laurent Mottron
1M ago
Clinicians diagnosing autism rely on diagnostic criteria and instruments in combination with an implicit knowledge based on clinical expertise of the specific signs and presentations associated with the condit ..read more
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Fetal brain growth and infant autistic traits
BMC » Molecular Autism
by Ezra Aydin, Alex Tsompanidis, Daren Chaplin, Rebecca Hawkes, Carrie Allison, Gerald Hackett, Topun Austin, Eglė Padaigaitė, Lidia V. Gabis, John Sucking, Rosemary Holt and Simon Baron-Cohen
2M ago
Structural differences exist in the brains of autistic individuals. To date only a few studies have explored the relationship between fetal brain growth and later infant autistic traits, and some have used fet ..read more
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Granulocyte macrophage colony-stimulating factor-induced macrophages of individuals with autism spectrum disorder adversely affect neuronal dendrites through the secretion of pro-inflammatory cytokines
BMC » Molecular Autism
by Ryohei Takada, Michihiro Toritsuka, Takahira Yamauchi, Rio Ishida, Yoshinori Kayashima, Yuki Nishi, Mitsuru Ishikawa, Kazuhiko Yamamuro, Minobu Ikehara, Takashi Komori, Yuki Noriyama, Kohei Kamikawa, Yasuhiko Saito, Hideyuki Okano and Manabu Makinodan
2M ago
A growing body of evidence suggests that immune dysfunction and inflammation in the peripheral tissues as well as the central nervous system are associated with the neurodevelopmental deficits observed in auti ..read more
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Naturally occurring low sociality in female rhesus monkeys: A tractable model for autism or not?
BMC » Molecular Autism
by Ozge Oztan, Laura A. Del Rosso, Sierra M. Simmons, Duyen K. K. Nguyen, Catherine F. Talbot, John P. Capitanio, Joseph P. Garner and Karen J. Parker
3M ago
Autism spectrum disorder (ASD) is characterized by persistent social interaction impairments and is male-biased in prevalence. We have established naturally occurring low sociality in male rhesus monkeys as a ..read more
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