“Diet and exercise” has been the weight-loss mantra for decades – but a drug designed for diabetes patients could now offer hope to people who are obese, at a time when researchers are warning that half of the world’s population are expected to be overweight or obese by 2035. One of the first to have injections of Semaglutide in the UK was Jan who's battled with her weight since childhood. Once the medication took effect she lost 4 stone and said her hunger disappeared. Professor Stephen O’Rahilly from the University of Cambridge explains how the drug mimics our body’s natural appetite signall ..read more

A month on from the devastating earthquakes in Turkey and Syria, we assess what kind of impact the disaster may have had on mental health. We hear from Professor Metin Basoglu, an expert in earthquake trauma and director of the Istanbul Centre for Behavioural Sciences. He explains how it is a unique kind of trauma rooted in fear and compounded by the uncontrollable nature of earthquakes and the thousands of aftershocks that come following the initial disaster. Prof Basoglu tells us about the psychological treatment he developed based on his research with 10,000 survivors of the 1999 earthquake ..read more

In this week’s Health Check we’re talking about the protective effects of vaccines – but it’s not quite what you think… We’re delving into the science of how some vaccines could have unexpected effects beyond their intended target. They’re called “non-specific effects” and we’re only just at the beginning of our understanding despite scientists documenting this curious biological phenomenon more than 100 years ago. One of the earliest vaccines to be studied was the Bacillus Calmette-Guérin vaccine for Tuberculosis, better known as the BCG. Professor Christine Stabell-Benn gives us a history le ..read more

Venomous snakebites are responsible for up to 150,000 deaths a year around the world – and they also leave around half a million survivors with life-changing injuries, including amputations and disfigurement. In this week’s Health Check we investigate why snakebite still disproportionately affects poorer, more rural communities, and what is being done to tackle the problem. We’ll talk to a mother in Kenya whose little girl was bitten by a snake not once, but twice, and to a doctor about how it feels to save lives. We’ll hear how anti-venoms are checked and how in many cases they are too expens ..read more

In this week’s programme we’re asking if changes in the weather can have an impact on our mental health. We go to Bangladesh in South Asia – a country on the front line of the impacts of climate change – where researchers have been exploring connections between incremental changes in heat and humidity, along with bigger impacts like flooding, and the levels of anxiety and depression in the population. You’ll have to listen to find out the answer – but they say their study has stark implications, not just for Bangladesh, but for many other countries too. Our studio guest today is Dr Belinda Fen ..read more

This week we’re dedicating the programme to a common medical emergency – one that can be deadly within minutes without the right help to hand. A cardiac arrest is when the heart suddenly stops pumping blood around the body. We’ll hear from a doctor who battled for five hours to save a man 40,000ft up in the air; a student who’s teaching people not to be afraid to help in an emergency and we’ll hear a survivor’s story of life after cardiac arrest. Globally, there are tens of thousands of cardiac arrests outside of hospital every year. Fewer than one in 10 survive and this number varies dependin ..read more

Six months on from the worst flooding in Pakistan’s history, a medic in eastern Balochistan describes what he is seeing daily. Khalid Saleem, who works for the charity Médecins Sans Frontières (Doctors Without Borders), says many people are still living in shelters at the side of the road and must walk miles if they need healthcare. There are high levels of malnutrition, malaria and skin conditions such as scabies. We also talk Professor Zainab Samad, from Aga Khan University in Islamabad, who is the author of a major new report on the country’s health. She describes how people in these areas ..read more

In this week’s episode we hear from two women who talk about what life is like with endometriosis, an incredibly common but debilitating condition where tissue similar to the lining of the womb grows in other places in the body. Katherine from Ghana and Dee from Wales describe their long journeys to diagnosis and how the “invisible illness” affects every aspect of their lives, from mental health to work and relationships. We also hear from a researcher in the US who is studying the condition in minute detail in the hope that arming the scientific community with deeper knowledge will help lead ..read more

Claudia Hammond explores the psychology of regret with an audience at the Cheltenham Science Festival. What role do rueful thoughts on "what might have been" play in our lives? Is regret a wasted emotion or does it have some hidden benefits? Joining Claudia on stage : Teresa McCormack - Professor of Cognitive Development at the School of Psychology, Queen's University Belfast who researches how regret in childhood can shape our decisions; novelist and essayist Sophie White - whose latest novel The Snag List examines the opportunity to go back in life and follow the road not taken; Fuschia Siro ..read more

Many people say that knitting or crochet helped ease their anxiety during the Covid-19 lockdowns. Claire Anketell set up free Yarn for Mental Health courses in Northern Ireland last year and Gemma McAdam says crochet helped to reduce her stress levels and she's now making blankets. Esther Rutter's book This Golden Fleece: A Journey through Britain's Knitted History aims to unpick what textiles mean to us - including how they became part of the treatment for mental health problems. Learning a skill by following a pattern, connecting with other people and being distracted from everyday worries t ..read more