Modeling the Body on a Few USB Sticks: The Power of Organs-on-Chips
A Closer Look at Stem Cells
by john parsley
2y ago
<p>Shallow breath in, shallow breath out. Your diaphragm contracts as you inhale, creating a vacuum, drawing air into your lungs. Then it relaxes as you exhale, pushing the air out. Whether you experienced this after a run last week, or the memory is ingrained from gym class, one thing is for sure: your lungs require mechanical forces to develop and function throughout life. It is critical to model the complex and dynamic forces that our organs depend on, both to understand how they develop and what goes wrong when they fail.</p> <p>While many biomedical advances have been ma ..read more
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Skyrocketing Science with Stem Cells in Space
A Closer Look at Stem Cells
by john parsley
2y ago
<p>Do you think stem cells floating in space could possibly help us down on Earth? This might sound far out, but scientists are finding that researching stem cells outside our planet could help us better understand the physiological changes to astronauts in orbit and, more broadly, provide key insights about disease progression and treatment on Earth.</p> <p><strong>When stem cells are out of this world</strong></p> <p>Space travel plucks us away from the pull of Earth&rsquo;s gravity and exposes us to solar radiation &ndash; novel conditions t ..read more
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Setting the Standards – New Stem Cell Research Guidelines Released
A Closer Look at Stem Cells
by john parsley
2y ago
<figure> <center><img src=”https://www.closerlookatstemcells.org/wp-content/uploads/2021/08/file-20210527-23-n1k71z-scaled.jpg” /> <figcaption> <span class=”attribution”><span class=”source”>Paul Sakuma/AP</span></span> </figcaption> </center></figure> <span><a href=”https://theconversation.com/profiles/megan-munsie-756″>Megan Munsie</a>, <em><a href=”https://theconversation.com/institutions/the-university-of-melbourne-722″>The University of Melbourne</a></em> and <a href=”https://the ..read more
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I’ll Take My Burger with a Side of Sustainability
A Closer Look at Stem Cells
by john parsley
2y ago
Imagine that a chef personally asks you to taste a new burger recipe. It looks medium rare as requested, has a satisfying texture, and most importantly, it tastes delightfully meaty. What if they tell you that the&nbsp;burger you just ate was better for animals, the environment, and your health? Then they tell you that the burger was not made from a cow, but rather, from stem cells in a lab. Does that change how you feel about your meal? </p> <p>Every year, humans consume 77 billion land animals, which has far-reaching consequences on the environment. Animal agriculture has det ..read more
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Can Stem Cell Research Save Endangered Species?
A Closer Look at Stem Cells
by john parsley
2y ago
“It’s like witnessing a funeral,” a spectator whispers as the Tasmanian artist Lucienne Rickard chafes a rubber eraser against a pencil portrait of the swift parrot. This critically endangered bird migrates between southeastern mainland Australia and Tasmania, where it breeds. Rickard has been <a href=”https://www.tmag.tas.gov.au/whats_on/exhibitions/current_upcoming/info/extinction_studies”>drawing and then erasing</a> meticulous replicas of extinct and threatened species to alert viewers of the ongoing assault on Earth&rsquo;s biodiversity (Figure 1). Even the loss of a singl ..read more
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The Universe of Universal Stem Cells: Rewards vs Risks
A Closer Look at Stem Cells
by john parsley
2y ago
Many incurable health problems are characterized by the death of cells that cannot regenerate or repair themselves upon damage or injury. For example, cardiac muscle cells die in heart attack, nerve cells perish in the brain during a stroke, and insulin-producing cells vanish in diabetes. Unfortunately, these cells are incapable of regeneration, leading to irreversible damage. Laboratory scientists are developing potential solutions to replace these cells.  Stem cell scientists are studying the use of stem cells to produce functional cells that could be transplanted into patients to ..read more
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Stem Cells May Offer Key to Treating Venomous Snake Bites
A Closer Look at Stem Cells
by john parsley
2y ago
Each year people around the world fall victim to about 1.8 – 2.7 million venomous snake bites. Many of these injuries go untreated due to lack of access to available treatments or health insurance, resulting in more than 100,000 deaths and approximately three times as many permanent disabilities. New therapies are needed to treat snakebite envenoming, a neglected public health issue. A new therapeutic tool to treat venomous snake bites may have come from an unlikely source &ndash; stem cell research.</p> <p>There are about 250 types of venomous snake species with the highest pr ..read more
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Closing in on Pluripotent Stem Cell Therapies for Liver Diseases
A Closer Look at Stem Cells
by john parsley
2y ago
The liver, our largest internal organ, plays vital roles in food metabolism, energy storage, and elimination of toxins. Liver disorders kill more than two million people per year, representing a significant global health challenge. In addition, liver failure is the end stage of many life-threatening diseases, such as alcoholic hepatitis, Hepatitis B infection, and liver cancer. In such conditions, liver failure results from the widespread death of the major cell type of the liver, the hepatocyte. <p style=”text-align: left;”>Organ transplantation is the only available therapeutic option ..read more
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Scientists Use Stem Cells to Uncover COVID-19 Effects on the Heart
A Closer Look at Stem Cells
by john parsley
2y ago
Scientists and medical professionals worldwide are collaborating to discover how to address the coronavirus pandemic and to better understand its effects on the body. It is well known that COVID-19 can devastate the lungs, causing symptoms including cough, shortness of breath, pneumonia, and acute respiratory distress syndrome<a href=”https://isscresearch-my.sharepoint.com/personal/jperlin_isscr_org/Documents/A%20closer%20look/Blog%202020/September%20-%20COVID%20and%20stem%20cells/ACL%20Sept%202020%20Blog%20Arun%20Sharma%20final.docx#_ENREF_2″ title=”Madjid, 2020 #5″></a>. However ..read more
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Basic Research: The Wind Beneath Innovation’s Wings
A Closer Look at Stem Cells
by john parsley
2y ago
<p>Biomedical research &ndash; the science of investigating the mechanisms and causes of disease &ndash; has been the driving force for many of the greatest medical advances in history: from drugs like penicillin to fight bacterial infections to medications like insulin to control diabetes. Its importance feels even more pertinent nowadays amidst the COVID-19 pandemic. While the wait for treatments might feel long, vaccine development is moving forward at an exceptional pace. Such rapid progress can be achieved because scientists are armed with the knowledge from earlier discover ..read more
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