With more than 200 types of cancer and every cancer individually unique, ongoing efforts to develop precision oncology treatments remain daunting. Most of the focus has been on developing genetic sequencing assays or analyses to identify mutations in cancer driver genes, then trying to match treatments that may work against those mutations ..read more

Polypharmacy, or the concurrent use of five or more medications, is common in older adults and increases the risk of adverse drug interactions. While deprescribing unnecessary drugs can combat this risk, the decision-making process can be complex and time-consuming. Increasingly, there is a need for effective polypharmacy management tools that can support short-staffed primary care practitioners ..read more

Myocardial infarction, more commonly known as a heart attack, is a leading cause of death worldwide. Biomarkers called plasma metabolites may play a key role in the physiological pathways involved in myocardial infarctions. Recently published research used a methodological approach called bidirectional Mendelian randomization to understand more about these biomarkers and what they can tell doctors about heart attack risk ..read more

Searching for evidence for health technology assessments (HTAs) is time-consuming because the evidence identified must be a reliable basis for robust assessment results: The scientific knowledge about the benefits and harms for patients must be completely available. This is why IQWiG's information specialists regularly review the effectiveness and efficiency of information retrieval conducted for the Institute's HTAs ..read more

The clinical knowledge and reasoning skills of GPT-4 are approaching the level of specialist eye doctors, a study led by the University of Cambridge has found ..read more

Researchers have used artificial intelligence techniques to massively accelerate the search for Parkinson's disease treatments ..read more

A new study examines the development of two machine learning models to classify the immunophenotype of a cancer specimen ..read more

Young breast cancer (BC) survivors (40 years or younger) without a pathogenic variant (PV) have a low risk for developing second primary BC (SPBC), according to a study published online April 11 in JAMA Oncology ..read more

An innovative new field of research holds the promise for pediatric cardiologists and heart surgeons to predict the future structural integrity of a child's heart valves so they can perform the best possible surgery today ..read more

With large language models that take notes during patient visits and algorithms that identify disease, artificial intelligence has begun to prove its worth as an assistant for physicians. But a new study from Stanford Medicine shows the potential of AI as a facilitator—one that helps doctors and nurses connect to achieve more efficient, effective patient care ..read more