Thrombolytic Dosing in PE: Versus Series Special Guest: Lauren Igneri, PharmD, BCPS, BCCCP, FCCM   05:20 – High-risk PE 23:00 – Intermediate-risk 37:10 – Cardiac arrest 52:30 – Closing arguments 57:15 – Bonus: TNK v. tPA   Reference List: https://pharmacytodose.files.wordpress.com/2024/04/thrombolytic-dosing-in-pe-references.pdf   PharmacyToDose.Com @PharmacyToDose PharmacyToDose@Gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices ..read more

Glycemic Control in the Critically Ill: Part II Special Guests: Judi Jacobi, PharmD, FCCP, MCCM, BCCCP @JudiJacobi Michael Sirimaturos, PharmD, BCNSP, BCCCP, FCCM @MSirimaturos   04:10 – Becoming panel members 11:50 – Guideline scope and PICO questions 21:35 – 2012 v. 2024 guidelines 28:05 – Effect of TGC-FAST 30:40 – 2024 guideline deep-dive 42:00 – Clinical decision support tools 50:00 – Pediatric recommendations 54:40 – Important future research topics 66:05 – Guideline manuscript writing 76:10 – Take-home points   Reference List: https://pharmacytodose.files.wordpress.com/2024/04 ..read more

Literature Review Series November 2023 Special Guests: Arjay Mendoza, PharmD, BCPS, AAHIVP Brock Townsend, PharmD @Townsend_PharmD   04:30 – Featured Articles 35:25 – Cardiology 48:05 – Precision-based medicine potpourri 58:50 – Infectious Diseases 69:10 – PharmD   Reference List: https://pharmacytodose.files.wordpress.com/2024/04/november-lrs-2023-references.pdf   PharmacyToDose.Com @PharmacyToDose PharmacyToDose@Gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices ..read more

Trial of the Week: SOAP II Special Guest: Jessica Casey, PharmD, BCPS, BCCP @jmc_cardspharmd   Jessica Casey joins to discuss the April Trial of the Week “Comparison of Dopamine and Norepinephrine in the Treatment of Shock,” the SOAP II study, published in NEJM in 2010. We set the scene by reviewing catecholamine vasopressor receptor physiology, guideline recommendations, and pre-SOAP II research. Then we do a deep dive into the SOAP II trial of the week. Did including all forms of shock help or hurt? How does the mortality in this study compare with others? Would this have been as positi ..read more

Trials of the Week: Landmark Nimodipine Studies Special Guest: Salia Farrokh, PharmD, BCCCP, FNCS @salia_farrokh   Salia Farrokh joins to highlight two landmark studies with nimodipine, “Cerebral Arterial Spasm – A Controlled Trial of Nimodipine in Patients with Subarachnoid Hemorrhage” published in NEJM in 1983 and “Effect of Oral Nimodipine on Cerebral Infarction and Outcome after Subarachnoid Hemorrhage: British Aneurysm Nimodipine Trial” published in 1989 in BMJ. We review aSAH treatments in the 1970’s and 1980’s and what evidence existed for nimodipine use before highlighting our two ..read more

Final Four Preview and More: 2024 Critical Care Trials March Madness Bracket   Sepsis/Fluids Bracketologist: Clay Small, PharmD, BCCCP CV/Pulm Bracketologist: Jolie Gallagher, PharmD, BCCCP Bleeding/BG Bracketologist: Jason Hecht, PharmD, BCPS, BCCCP, FCCM Neuro/PADIS Bracketologist: Karen Berger, PharmD, FASHP, FCCM, BCPS, BCCCP   06:10 – Region recaps 32:10 – Final Four preview and predictions 45:30 – Revisiting pre-tournament predictions   PubMed links for all 68 Critical Care March Madness trials: https://pharmacytodose.files.wordpress.com/2024/03/critical-care-trials-refere ..read more

Literature Review Series October 2023 Special Guests: Hailey Burns, PharmD @Hailey_rx36 Caitlyn Simonson, PharmD   03:45 – Featured Articles 38:15 – Neuro 50:10 – EM/Tox/Trauma 61:50 – Renal/Endocrine 66:38 – PharmD 70:10 – Sweet Emotion   Reference List: https://pharmacytodose.files.wordpress.com/2024/03/october-lrs-2023-references.pdf   PharmacyToDose.Com @PharmacyToDose PharmacyToDose@Gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices ..read more

Sweet 16 Preview and Recap: 2024 Critical Care Trials March Madness Bracket Preview   04:06 – First round recap 13:25 – Second round recap 19:05 – Sweet 16 preview   PubMed links for all 68 Critical Care March Madness trials: https://pharmacytodose.files.wordpress.com/2024/03/critical-care-trials-reference-list-all-regions.pdf   2024 March Madness Bracket: https://pharmacytodose.com/2024/03/17/2024-critical-care-trials-march-madness-bracket/   PharmacyToDose.Com @PharmacyToDose PharmacyToDose@Gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices ..read more

Pharmacotherapy in the Critically Ill Pregnant Patient: Part II Special Guests: Allison Lankford, MD Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP @mtbastin   04:50 – Obstetric hemorrhage 18:20 – Ectopic pregnancy 22:30 – Hypertensive emergency 28:45 – Pre-eclampsia/eclampsia 35:00 – Lactation considerations 39:35 – Take-home points   Pharmacotherapy “Caring for two in the ICU” articles: Part I: https://pubmed.ncbi.nlm.nih.gov/36938691/ Part II: https://pubmed.ncbi.nlm.nih.gov/37323102/   PharmacyToDose.Com @PharmacyToDose PharmacyToDose@Gmail.com Learn more about your ..read more

2024 Critical Care Trials March Madness Bracket Preview: Part II Cardiac/Pulmonary and Sepsis/Fluids Regions   CV/Pulm Bracketologist: Jolie Gallagher, PharmD, BCCCP Sepsis/Fluids Bracketologist: Clay Small, PharmD, BCCCP   PubMed links for all 68 Critical Care March Madness trials: https://pharmacytodose.files.wordpress.com/2024/03/critical-care-trials-reference-list-all-regions.pdf   2024 March Madness Bracket: https://pharmacytodose.com/2024/03/17/2024-critical-care-trials-march-madness-bracket/   PharmacyToDose.Com @PharmacyToDose PharmacyToDose@Gmail.com Learn more abo ..read more