Clinical characteristics of patients with psoriasis with family history: A multicenter observational study
Wiley Online Library » The Journal of Dermatology
by Chika Ohata, Hisataka Anezaki, Sakae Kaneko, Fusako Okazaki, Kotaro Ito, Yuki Matsuzaka, Satoko Kikuchi, Yuta Koike, Hiroyuki Murota, Takuya Miyagi, Kenzo Takahashi, Kazunari Sugita, Aki Hashimoto, Takeshi Nakahara, Shin Morizane, Bungo Ohyama, Hiroshi Saruwatari, Tetsuji Yanase, Yuichi Yoshida, Kentaro Yonekura, Yuko Higashi, Yutaka Hatano, Kanami Saito, Eri Katayama, Mariko Yamane, Fumikazu Yamazaki, Noriko Tsuruta, Shinichi Imafuku
6d ago
Abstract Previous studies on family history of psoriasis showed that patients with a family history have an earlier onset of the disease, but such studies in Japan are still limited. To elucidate the characteristics of patients with familial psoriasis, we studied the family history of patients with psoriasis using the West Japan Psoriasis Registry, a multi-institutional registry operated by 26 facilities in the western part of Japan, including university hospitals, community hospitals, and clinics. This study enrolled 1847 patients registered between September 2019 and December 2021, with 199 ..read more
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Successful treatment of epidermolysis bullosa pruriginosa by dupilumab
Wiley Online Library » The Journal of Dermatology
by Xue‐Ge Wu, Shi Yan, Jin‐Qiu Jiang, Tian‐Tian Zhou, Xiao Fang, Huan Yang, Xiao‐Ming Bai, Hua Wang, Xiaoyan Luo
6d ago
Abstract Epidermolysis bullosa pruriginosa (EBP) is a rare variant of dystrophic epidermolysis bullosa caused by COL7A1 gene mutation. Intense pruritus and nodular prurigo-like lesions are the main features of the disease. To date, the treatment strategies for this condition are not well established. Recent studies have indicated that type 2 inflammation plays a role in the pathophysiology of EBP, suggesting Th2 cytokines could be potential therapeutic targets. In this prospective case series study, we reported three patients with EBP, diagnosed by clinical manifestations, histopathological ev ..read more
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A case of Kimura disease with atopic dermatitis successfully treated with baricitinib
Wiley Online Library » The Journal of Dermatology
by Marina Ueda, Toshiaki Kogame, Gyohei Egawa, Naotomo Kambe, Kenji Kabashima
1w ago
The Journal of Dermatology, EarlyView ..read more
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Cutaneous manifestations in elderly patients with confirmed coronavirus disease 2019 and the disease outcomes: A systematic review
Wiley Online Library » The Journal of Dermatology
by Shannaz Nadia Yusharyahya, Valdi Ven Japranata, Reganedgary Jonlean, Lili Legiawati, Rinadewi Astriningrum
1w ago
Abstract Cutaneous manifestations in coronavirus disease 2019 (COVID-19) patients may possess prognostic value for identifying potentially severe cases. This systematic review investigated whether dermatological features are associated with COVID-19 outcomes in elderly patients. Literature retrieval was conducted on May 11, 2022, from databases, hand-searching, and tracing citations. Following selection against eligibility criteria, the remaining records were evaluated utilizing the National Heart, Lung, and Blood Institute Study Quality Assessment Tool or Newcastle–Ottawa Scale. The pooled in ..read more
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Preface to The Journal of Dermatology special issue: What's new in autoimmune bullous diseases
Wiley Online Library » The Journal of Dermatology
by Daisuke Tsuruta
1w ago
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Biologics in pediatric psoriasis
Wiley Online Library » The Journal of Dermatology
by Wen‐Ming Wang, Hong‐Zhong Jin
1w ago
Abstract Psoriasis is a chronic inflammatory skin disorder with a chronic relapsing course. Biologics have revolutionized the treatment of adult psoriasis with higher efficacy and favorable safety profile. Recently, more studies have focused on the use of biologics in pediatric psoriasis, and several biologics have been approved for use therein. This review is divided into two sections: the first part focuses on real-world studies on the use of biologics in pediatric psoriasis and the second part summarizes the findings of other clinical trials related to biologics in pediatric psoriasis. Case ..read more
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Association between the first exposure to general anesthesia and alopecia areata
Wiley Online Library » The Journal of Dermatology
by Heera Lee, Young Woong Choi, You Chan Kim, Jee Woong Choi
1w ago
Abstract Alopecia areata (AA) is an autoimmune cutaneous disorder reported to be related to various immunologic diseases and psychiatric disorders. Some AA patients report the onset of patchy hair loss after surgeries under general anesthesia (GA). However, no large-scale studies have been conducted on the relationship between AA and GA. Thus, we aimed to evaluate whether exposure to GA is associated with an increased risk of AA. In this retrospective study, we analyzed a population exposed to GA. These individuals were compared to unexposed controls, matched by age, sex, income level, and com ..read more
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IL‐31 and IL‐31 receptor alpha in pemphigus: Contributors to more than just itch?
Wiley Online Library » The Journal of Dermatology
by Satoshi Okuno, Takashi Hashimoto, Yuki Yamazaki, Manami Okuzawa, Takahiro Satoh
1w ago
Abstract Pemphigus is an autoimmune blistering disorder with four major subtypes: pemphigus vulgaris (PV), pemphigus vegetans (PVe), pemphigus foliaceus (PF), and pemphigus herpetiformis (PH). Among them, PF and PH present itching as a clinical feature; however, the mechanisms behind the pruritus are still unclear. In this report, we sought to investigate the expression of a type 2 inflammation-related pruritogenic cytokine IL-31 and its receptor subunit IL-31RA through immunofluorescence staining analysis. The number of eosinophils, basophils, and mast cells, and the expression levels of thym ..read more
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Trichoblastic carcinosarcoma of the neck: Case report and molecular analysis of a seldom, relapsing entity and a review of the literature
Wiley Online Library » The Journal of Dermatology
by Thomas Weiland, Birgit Sadoghi, Prisca Pondorfer, Peter Kiss, Iva Brcic, Dietmar Thurnher
1w ago
Abstract Trichoblastic carcinosarcoma is a seldom biphasic adnexal tumor with malignant epithelial and mesenchymal components. The authors report the first tumor on the neck developed from preexistent trichoblastoma showing aggressive, recurrent behavior. An 82-year-old man presented with a solitary 3-cm exophytic lesion. Histology verified the diagnosis of trichoblastic carcinosarcoma. Four years earlier, a trichoblastic carcinoma arising in a preexisting trichoblastoma was excised at the same location. Despite successful surgical treatments, three local recurrences within 4 years were diagno ..read more
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Successful treatment of cutaneous Mycobacterium chelonae infection by switching from levofloxacin to sitafloxacin
Wiley Online Library » The Journal of Dermatology
by Takuo Murakami, Naohiko Aozasa, Hanako Fukano, Yuji Miyamoto, Norihisa Ishii, Yuichiro Tsunemi, Koichiro Nakamura
1w ago
The Journal of Dermatology, EarlyView ..read more
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