Aging is an inevitable and normal biological process in humans. Like all human organs, your skin ages and, as you get older, starts exhibiting telltale signs of biological aging (senescence): wrinkles, sagging, and loss of moisture and fat. While numerous factors such as genetics and lifestyle can accelerate the process, research has helped identify aging mechanisms that can be targeted to slow down or delay the appearance of visible signs of aging on skin. Consequently, the multibillion-dollar beauty industry offers a vast array of products and procedures that promise a more youthful complexi ..read more

As eager as one may be to greet a newborn, an early arrival is never good. Preterm birth (PTB) — when an infant is born before 37 weeks of gestation — is a serious problem across the globe. With an estimated 15 million cases annually, spontaneous preterm birth (SPTB) is the leading cause of death in infants under the age of five years. Of the numerous risk factors linked to PTB, ascending bacterial infections of the uterine cavity account for the vast majority of spontaneous preterm births. Therefore, the cervicovaginal microbiome has received increased scrutiny in recent years. Preterm birth ..read more

Alzheimer’s disease (AD) is a devastating neurodegenerative disease causing neuropathological changes and a severe decline in cognitive function. The most common cause of dementia, AD has no known cure. Although some medications may delay the loss of cognition and memory, definitive interventions are elusive. Recent research has focused on the role of the human microbiome in regulating multiple neurochemical pathways through the gut-brain axis and on looking for new therapeutic approaches for microbiota modulation. Alzheimer’s disease, in brief It is estimated that more than 50 million people ..read more

Bariatric surgery improves metabolism and inflammation in severe obesity and is associated with gut microbiota modifications. However, the role of the gut microbiota in inducing these beneficial changes is controversial in part because the surgery may not fully restore microbial balance. Recent research has attempted to disentangle the complex relationship as well as elucidate a potential benefit for the use of probiotics in bariatric patients. Bariatric surgery, in brief A dramatic rise in extreme obesity over the last few decades has led to a subsequent burst in bariatric surgical procedures ..read more

Traumatic brain injury (TBI) is a global public health issue affecting many millions each year. Management requires an understanding of both the primary brain injury and the secondary sequelae that affect peripheral organs, including the gastrointestinal (GI) tract. The gut-brain axis is composed of bidirectional pathways between the gut and brain, hence TBI-induced neuroinflammation and neurodegeneration also impact gut function, which in turn influences secondary injury progression. Restoration of the gut microbiome to modulate the pathways may be a promising avenue for therapy in TBI. Traum ..read more

https://www.teknoscienze.com/wp-content/uploads/2022/04/Editorial_AF1_2022.pdf The Gut Brain Axis, or commonly referred to as the “GBX” is the most researched area after Gastrointestinal an Immune health within the probiotic category. Moreover, the pandemic has emphasized and brought ‘mental health’ into the mainstream and made it “top of mind” as a matter that must be dealt with both during the pandemic and post-pandemic. The scientific research is expanding rapidly into areas of dietary supplements, and also investigating probiotic interventions in mental health conditions previously treated ..read more

As the research into the microbiome continues to find applications in health, customers, retailers, and marketers struggle with understanding or creating product messaging. A recent panel discussion addressed these concerns and provided practical steps to reduce confusion and stay out of reach of regulatory crosshairs. IPA’s Director of Education and Communication Sandra Saville RD was joined by Kristina Campbell of KC Microbiome Communications and Traci Kantowski of the Global Probiotic Association in a panel titled How to Communicate the Microbiome in a Responsible, Resonating Way. The prese ..read more

In 2020, 2.3 million women worldwide were diagnosed with breast cancer. The most frequently identified female cancer, breast cancer has links to changes in the gut and mammary microbiota. The microbiota at these sites appear to influence breast cancer risk, response to treatment, and recurrence. Since the early 2000s, the role of the human gut/ mammary microbiota and potential relevance in breast cancer has become a major area of interest in the scientific and medical communities.  This article (Part 1) will focus on how the gut and mammary microbiota and related dysbiosis (disrupted micr ..read more

Sometimes called uterine cancer, endometrial cancer begins in the layer of cells lining the uterus. Due to emerging evidence that the uterus is not a sterile cavity, researchers have begun to investigate the endometrial microbiome and its possible role in endometrial cancer. Endometrial cancer, in brief The endometrium is dynamic tissue, responding to estrogen and progesterone by thickening in preparation to nourish a fetus and shedding (menstruation) each month when not needed. Endometrial cancer risk is increased by advanced age, early onset of menses, late menopause, nulliparity (no births ..read more

Postbiotics are emerging as potent forces for health, just as with probiotics, prebiotics and synbiotics. But unlike these related substances, the term postbiotic continues to cause no small amount of confusion. Postbiotics, an evolving definition Researchers working with probiotics observed that at times isolated factors produced by the probiotic activity elicited the desired response. They called these factors postbiotics. This early characterization continued to change and evolve as the components were further studied. The current Wikipedia definition states that “postbiotics— also known as ..read more