The oral microbiome: a double face in health and disease
Gut Microbiota Health
by Germano Orrù
3d ago
The educational content in this post, elaborated in collaboration with Bromatech, was independently developed and approved by the GMFH publishing team and editorial board. Why oral microbiome matters? When we think about the vast community of bacteria living in our mouths, it’s fascinating to realize that at least 1,000 different species, organized into nine groups, have been identified. Most of these bacteria are harmless and do not typically cause diseases in healthy individuals, but can cause problems in circumstances like illness, medical treatments like chemotherapy, and when the body’s i ..read more
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Unlocking the diagnostic and therapeutic potential roles of gut microbiome: takeaways from the 2024 GMFH Summit
Gut Microbiota Health
by Joël Doré
3w ago
Microbiome-based therapeutics and precision medicine for better health Eran Elinav from the Weizmann Institute of Science (Israel) and German Cancer Research Center (Germany) kicked off the conference by highlighting that the current ‘one size fits all’ microbiome treatment approach is outdated and that we should create a new microbiome and clinical data-driven therapeutic ‘toolbox’. The targeted suppression of human gut commensals contributing to non-communicable diseases remains an unmet challenge. Elinav shared first-of-its-kind findings on using an orally administered cocktail of phages to ..read more
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Feed your microbes to improve gut and mental health
Gut Microbiota Health
by GMFH Editing Team
3w ago
Why does the microbiota-gut-brain axis matter? While the existence of a link between the gut and the brain has recently gained growing attention from the media, the concept of the gut-brain axis is not new. In the 19th and 20th centuries, work from different scientists and physicians, such as William Beumont, Charles Darwin, and Claude Bernard linked gut and digestion to emotions. Later on, studies suggested that the huge community of microorganisms living in the gut are important players in the gut-brain axis, which has led to the term ‘microbiota-gut-brain axis1. The microbiota-gut-brain axi ..read more
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Dysosmobacter welbionis as potential promising next-generation probiotic for improving metabolic health?
Gut Microbiota Health
by Patrice D. Cani
1M ago
Dysosmobacter welbionis J115T is a butyrate-producing commensal bacterium isolated from the human gut in 2017 that has been detected in about 70% of the general population, in a similar amount to Akkermansia muciniphila. Previous research revealed that D. welbionis was associated with lower body mass index, fasting glucose, and improved glycemic control in patients with obesity and type 2 diabetes. While preliminary findings showed treatment with D. welbionis J115T leads to lower weight and fat mass gain and improved glucose metabolism in high-fat diet-fed mice, little is known about how this ..read more
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Fermented foods: fleeting fad or dietary must-have?
Gut Microbiota Health
by Mónica Quinzo
1M ago
The role of fermented foods in gut health Enhancing human health is an evolving strategy, and one intriguing aspect is the modulation of the microbiome by consuming fermented foods as part of a healthy diet. However, understanding the mechanisms underlying the dos and don’ts of a particular food is essential for making informed health decisions. Fermented foods are defined as those made through desired microbial growth and enzymatic conversions of food components. During fermentation, microorganisms transform raw materials, altering the nutritional composition and bioactive properties of foods ..read more
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What role do gut and urogenital microbiomes play in urogenital infections?
Gut Microbiota Health
by Fabio Chiesa
2M ago
The educational content in this post, elaborated in collaboration with Bromatech, was independently developed and approved by the GMFH publishing team and editorial board. Once thought to be sterile, the bladder contains microbes that could influence health Nowadays, it is quite interesting to see how omics sciences are advancing our knowledge; the molecular techniques of genomics, metagenomics, and proteomics can precisely determine the composition and diversity of the microbial communities that are present in various anatomical sites and can identify metabolites that are produced by microorg ..read more
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Understanding the gut microbiota’s impact on longevity
Gut Microbiota Health
by Manon Oliero
2M ago
The educational content in this post, elaborated in collaboration with Lesaffre, was independently developed and approved by the GMFH publishing team and editorial board. What role does gut microbiota play in healthy aging? Aging, defined as the progressive decline in physiological function and cellular integrity over time, is accompanied by an increased susceptibility to various diseases, including cancer, obesity, and neurodegenerative disorders like Alzheimer’s disease. As life expectancy rises globally, ensuring healthy aging has become an urgent concern. The aim is to maintain physical an ..read more
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We have a real jungle in the colon!
Gut Microbiota Health
by Cristina Sáez
3M ago
Do you remember that 1987 movie, “Innerspace“? In it, a pilot commands a miniaturized ship that, by mistake, travels through the body of a very hypochondriac man. Well, if we could, like that pilot, reduce ourselves to just a few millimeters, put on a safari hat, and travel equipped with an explorer’s kit to our intestine, we would discover that it is nothing like the gloomy place we might imagine, dark, where lonely, sad, and hungry bacteria huddle together. Far from it! We would discover that our colon is a real jungle where, instead of trees, insects, and animals, we mainly harbor bacteria ..read more
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A probiotic for metabolic liver diseases?
Gut Microbiota Health
by Hervé Blottière
3M ago
Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), is the most common chronic liver disease worldwide, affecting more than 30% of population. This type of steatosis is caused by factors other than excessive alcohol use and occurs alongside other metabolic disorders such as obesity. While early-stage MASLD does not usually cause any harm, it can lead to an increased risk of liver transplantation and hepatocellular carcinoma. While the exact cause of MASLD isn’t completely understood, recently an altered gut microbiome h ..read more
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Gut microbiome in 2023: current and emerging research trends
Gut Microbiota Health
by GMFH Editing Team
3M ago
As in the beginning of every new year, it is time to look back at the latest scientific and medical advances in the gut microbiome arena during the past 12 months. The “Year at a Glance” document is now available and summarizes recent advances involving the microbiome in diagnosing, preventing, or managing gastrointestinal and systemic diseases. The 2023 edition of “Year at a Glance” starts by focusing on the role of intestinal barrier dysfunction (inaccurately referred in the media as “leaky gut”) in gastrointestinal health and disease, with a particular attention to dietary patterns and micr ..read more
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