A novel oxygen-doped graphitic carbon nitride (OCN) material was designed and synthesized via the hydrothermal-calcination method with melamine and hydroperoxide as starting materials. The OCN material was utilized as a highly efficient solid metal-free photocatalyst for the synthesis of 3-arylquinoxalin-2(1H)-ones via the catalytic decomposition of aryl diazonium salts under blue light irradiation. Following this approach, various 3-arylquinoxalin-2(1H)-one derivatives could be obtained in moderate to excellent yields with broad substrate scope under mild conditions. Also, the OCN solid photo ..read more

Modified crown ethers are fundamental building blocks in supramolecular chemistry, with applications in phase transfer catalysis, metal extraction, smart materials, and molecular machines. Here we report on a one-pot highly chemo- and regioselective photocatalytic fluoroalkylation protocol for the mono-functionalization of benzo substituted crown ethers. For this important class of macrocycles, the method described here represents one of the few late-stage functionalization procedures that is both high yielding and scalable. Because of its breadth of scope and substrate tolerance, the devised ..read more

In this Guest Editorial, Varinder Aggarwal, Zuowei Xie and Hajime Ito introduce the joint EurJOC/AsianJOC special collection on boron chemistry, which features original research and review articles on the synthesis and applications of organoboron compounds from researchers around the world ..read more

The novel synthetic approach was employed to synthesize a series of 1,8-dihydropyrazolo[3,4-b]azepine derivatives from 5-aminopyrazoles in three-step synthesis. The structures of the individual derivatives were unambiguously confirmed by spectral methods, including heteronuclear 1H –13C HMBC spectra and other necessary 2D NMR experiments. The obtained pyrazoloazepines and starting aminopyrazoles were subsequently investigated for their potential cytotoxic effect using mouse and human leukemia cell models. The original L1210 (mouse lymphoblastic), MOLM-13, and SKM-1 (both human myeloblastic) ce ..read more

Ethylenediamine bridged dibenzoxazine proligands were synthesized by a modified Mannich condensation reaction. The reaction of the proligands with two equivalents of AlMe3 resulted in the formation of dinuclear Al(III) compounds in high yield and purity. When the ligand binds to the Al(III) center, it forms two separate six membered N,O chelates with the two Al atoms that resembles the N-alkylated salan moiety. Each aluminum atom adopts a distorted tetrahedral geometry as revealed from the single-crystal X-ray diffraction studies of 1. The catalytic activity of these aluminum compounds was inv ..read more

An efficient regio- and site-selective desaturation and β-nitration of cyclic aliphatic amides through a selective HAT/oxidative desaturation/electrophilic nitration process was realized. Abstract Described herein is the development of a desaturation and N-β-nitration reaction of cyclic amides, which is achieved by a selective hydrogen atom transfer (HAT)/oxidative desaturation/electrophilic nitration process. In this procedure, di-tert-butyl peroxide (DTBP) acted both as the oxidant and HAT reagent, and electrophilic NOBF4 as nitration source. Notably, the application of produced cyclic nit ..read more

The Pd-catalyzed amino- and alkoxycarbonylation of aryl iodides has been exploited, for the first time, in a bioinspired Deep Eutectic Solvent and in gas-free conditions, by using Mo(CO)6 as the CO source. The method allows the preparation of carboxylic amides and esters in high yields (up to 99%), short reaction time (2 h) and in mild reaction conditions (80 °C), with a low catalyst loading (2.5 mol%). Noteworthy, in the case of N-hexylbenzamide, it has been demonstrated that both the catalyst and DES can be used for four consecutive runs, with a moderate decrease of catalytic efficiency. The ..read more

A methodology for the formal addition of β-acylalkenyl anions was developed by utilizing the [1,2]-phospha-Brook rearrangement under Brønsted base catalysis. The two-step reaction involves the catalytic addition of α-oxygenated propargyl anions generated via [1,2]-phospha-Brook rearrangement to electron-deficient ketones and subsequent alcoholysis to afford tertiary alcohols having an enone moiety. This is a rare example of a catalytic carbon-carbon bond forming reaction of β-acylalkenyl anion equivalents, providing synthetic building blocks that are otherwise difficult to access ..read more

The Front Cover shows a new class of bloody-red sulfur compounds, so called tetrathiaporphyrines, which could be isolated from some wild onions (genus Allium L.). These plants are known as drumstick onions and belong to the subgenus Melanocrommyum. This pigment is formed enzymatically if plant tissue is injured. Now, the colour-giving tetrathiaporphyrine, representing a new class of chemical pigments, could be fully synthesized, using 2-thiocyanato-1H-pyrrole as starting block. The final structure of the pigment was confirmed by X-ray crystallography of the reddish, flat crystals. More inform ..read more

The Front Cover illustrates the natural environment that needs to be protected by following the principles of 3Rs (Reduce, Reuse, and Recycle). The background of the picture shows our institute's riverfront, where a reusable polymer-supported aminocatalyst was developed for the sustainable synthesis of chiral amino acid derivatives. Cover design by Ms. Gayathri Chandrakumar. More information can be found in the Research Article by C. Appayee et al ..read more