Ep. 69: Past and Future of Endotoxin Testing
Sounds of Science
by Charles River
2w ago
Norm Wainwright and Foster Jordan have been immersed in the field of limulus amebocyte lysate (LAL) testing for decades, and have seen the progress and refinement of this crucial safety test. With the 20th anniversary of Charles River's Endosafe Cartridge and the recent introduction of recombinant alternatives, we look back at the past and future of endotoxin testing ..read more
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Ep. 68: Looking Ahead in 2024
Sounds of Science
by Charles River
1M ago
I am joined by four experts in their field to discuss what will be hot in rare diseases, drug discovery, artificial intelligence, and animal models in 2024.  ..read more
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Ep. 67: A Rare Diagnosis
Sounds of Science
by Charles River
2M ago
Molly Dupre, a lab assistant at Charles River's Reno site, was recently diagnosed with Niemann-Pick Type B/ Acid Sphingomyelinase Deficiency. After years of waiting, doctor's visits, and tests, she could finally put a name to the condition that flared up after the birth of her son. But what came next? She joins me to tell her story ..read more
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Ep. 66: When Drug Candidates Miss the Mark: Off-Target Liability
Sounds of Science
by Charles River
3M ago
Senior Principal Scientific Advisor Stan Spence joins me to discuss off-target liability: what happens when a drug misses its target? What are the risks to the patient if the off-target effects aren't caught early? Has there ever been an example of an off-target effect being beneficial to the patient? Find out here ..read more
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BONUS: Life After Cancer With Rachel and Susan
Sounds of Science
by Charles River
4M ago
Rachel Kiserow and Susan Desmond have joined us year after year as part of Eureka's Breast Cancer Roundtable. This year, they wanted to share what happens after - after the treatments, after remission - life after cancer ..read more
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Ep. 65: The New England Compounding Center Tragedy
Sounds of Science
by Charles River
5M ago
For this episode, I am joined by Charles River's Doug Botkin and Pure Microbiology's Abby Roth to discuss the 2012 NECC meningitis outbreak. Doug and Abby bring their background in microbiology to explain how it happened, and how we can prevent such tragedies in the future.  ..read more
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Ep. 64: State of Oncology Report
Sounds of Science
by Charles River
6M ago
Charles River experts Justin Bryans and Elizabeth Anderson join me for a spirited discussion of where we are now in oncology research. Could we ever see a world without cancer ..read more
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Ep. 63: Gene Therapy Manufacturing: Two Perspectives
Sounds of Science
by Charles River
7M ago
Manufacturing gene therapies is a hot topic in the pharma field, on both the supplier and the client ends. Joining me to discuss this issue is Charles River Associate Director of Gene Therapy, Andrew Frazer, and Purespring Therapeutics' VP of Chemistry, Manufacturing and Controls, Amanda Weiss.  ..read more
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Ep. 62: The Value of N-of-1 Research
Sounds of Science
by Charles River
8M ago
Dr. Lauren Black and Dr. Monkol Lek are both committed to the research and advancement of rare disease treatments. But when you are trying to treat just one patient, what can you learn that could help many more? We discuss the importance of n-of-1 studies, not just for that one patient and their families, but for anyone who might someday need a rare cure ..read more
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Ep. 61: Michael Hakeem on Recruiting Diversity Globally
Sounds of Science
by Charles River
9M ago
Through his own first-hand experience, Charles River Senior Director of Global Talent Acquisition Michael Hakeem knows the importance of diversity in hiring. He joins us this Pride Month to talk about his experiences and his insight into a thoughtful approach to recruiting for a company as large as Charles River ..read more
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