Correspondence to “Bipolar disorder-iPSC derived neural progenitor cells exhibit dysregulation of store-operated Ca2+ entry and accelerated differentiation” by Hewitt et al. (PMID: 37402854)
Nature » Stem cells
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1M ago
Correspondence to “Bipolar disorder-iPSC derived neural progenitor cells exhibit dysregulation of store-operated Ca entry and accelerated differentiation” by Hewitt et al. (PMID: 37402854 ..read more
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Advances and challenges in modeling inherited peripheral neuropathies using iPSCs
Nature » Stem cells
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1M ago
Advances and challenges in modeling inherited peripheral neuropathies using iPSCs ..read more
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Analysis of human neuronal cells carrying ASTN2 deletion associated with psychiatric disorders
Nature » Stem cells
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1M ago
Analysis of human neuronal cells carrying deletion associated with psychiatric disorders ..read more
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The properties of absorbable scaffold harvested with human amniotic fluid stem cells on rat model: an innovation for pelvic reconstruction surgery
Nature » Stem cells
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1M ago
The properties of absorbable scaffold harvested with human amniotic fluid stem cells on rat model: an innovation for pelvic reconstruction surgery ..read more
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XIST dampens X chromosome activity in a SPEN-dependent manner during early human development
Nature » Stem cells
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1M ago
XIST dampens X chromosome activity in a SPEN-dependent manner during early human development Using naive human embryonic stem cells as a model for early embryogenesis, the authors report that the XIST (X-inactive specific transcript) long noncoding RNA recruits repressive histone marks and attenuates X chromosome expression before the establishment of X chromosome inactivation ..read more
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Prognostic factors impacting post-transplant outcomes in adult T-cell acute lymphoblastic leukemia: a registry-based study by the EBMT acute leukemia working party
Nature » Stem cells
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1M ago
Prognostic factors impacting post-transplant outcomes in adult T-cell acute lymphoblastic leukemia: a registry-based study by the EBMT acute leukemia working party ..read more
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Cardiac ACTN2 enhancer regulates cardiometabolism and maturation
Nature » Stem cells
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1M ago
enhancer regulates cardiometabolism and maturation A study describes the role of the enhancer in myocardial maturation, highlighting its relevance in regulating structural, functional and metabolic dynamics in the heart. These findings offer insights that may advance our understanding of cardiovascular disease ..read more
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Non-hierarchically related HSCs replenish platelets by distinct progenitor pathways
Nature » Stem cells
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1M ago
Non-hierarchically related HSCs replenish platelets by distinct progenitor pathways Genetic lineage tracing and progenitor and multilineage fate mapping after single hematopoietic stem cell (HSC) transplantations identify two distinct HSC-progenitor trajectories for the replenishment of platelets in mice. These pathways include a slower multilineage pathway and a faster platelet-restricted or biased pathway, initiated by distinct and non-hierarchically related HSCs ..read more
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Lab-grown sperm and eggs: ‘epigenetic’ reset in human cells paves the way
Nature » Stem cells
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1M ago
Lab-grown sperm and eggs: ‘epigenetic’ reset in human cells paves the way Technique wipes away tags on DNA that must be reprogrammed during development of reproductive cells ..read more
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Acquisition of epithelial plasticity in human chronic liver disease
Nature » Stem cells
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1M ago
Acquisition of epithelial plasticity in human chronic liver disease Single-cell RNA sequencing and 3D imaging have revealed the cellular changes and structural reorganization that occur during the progression of human chronic liver disease and as the liver attempts to regenerate ..read more
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