A map of mouse embryogenesis
Nature » Stem cells
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3d ago
Exosomes derived from mesenchymal stem cells in diabetes and diabetic complications ..read more
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Reprogramming fibroblast into human iBlastoids
Nature » Stem cells
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3d ago
A protocol for the generation of induced blastoids, an in vitro integrated model of the human blastocyst derived via somatic reprogramming. This model overcomes restrictions associated with the use of human blastocysts in embryology research ..read more
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Exosomes derived from mesenchymal stem cells in diabetes and diabetic complications
Nature » Stem cells
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3d ago
Exosomes derived from mesenchymal stem cells in diabetes and diabetic complications ..read more
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De novo reconstruction of a functional in vivo-like equine endometrium using collagen-based tissue engineering
Nature » Stem cells
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3d ago
De novo reconstruction of a functional in vivo-like equine endometrium using collagen-based tissue engineering ..read more
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Aging-induced MCPH1 translocation activates necroptosis and impairs hematopoietic stem cell function
Nature » Stem cells
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3d ago
Aging-induced MCPH1 translocation activates necroptosis and impairs hematopoietic stem cell function He et al. characterizes a role of microcephalin (MCPH1), a known regulator of DNA damage response, in hematopoietic stem cell (HSC) aging demonstrating nuclear MCPH1 translocation that leads to activation of necroptosis and deterioration of HSC function with age ..read more
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Epigenetic modulation through BET bromodomain inhibitors as a novel therapeutic strategy for progranulin-deficient frontotemporal dementia
Nature » Stem cells
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3d ago
Epigenetic modulation through BET bromodomain inhibitors as a novel therapeutic strategy for progranulin-deficient frontotemporal dementia ..read more
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‘Mini liver’ will grow in person’s own lymph node in bold new trial
Nature » Stem cells
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2w ago
‘Mini liver’ will grow in person’s own lymph node in bold new trial Biotechnology firm LyGenesis has injected donor cells into a person with liver failure for the first time ..read more
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Dynamic molecular network analysis of iPSC-Purkinje cells differentiation delineates roles of ISG15 in SCA1 at the earliest stage
Nature » Stem cells
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2w ago
Dynamic molecular network analysis of iPSC-Purkinje cells differentiation delineates roles of ISG15 in SCA1 at the earliest stage Molecular changes in neurodegeneration occur much earlier than previously expected. In this study, dynamic molecular network analysis of iPSC differentiation uncovers a temporal pathway from histone to ISG15 with the earliest molecular changes of SCA1 ..read more
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Thiamine-modified metabolic reprogramming of human pluripotent stem cell-derived cardiomyocyte under space microgravity
Nature » Stem cells
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2w ago
Thiamine-modified metabolic reprogramming of human pluripotent stem cell-derived cardiomyocyte under space microgravity ..read more
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Umbilical cord mesenchymal stem cell-derived exosomes inhibits fibrosis in human endometrial stromal cells via miR-140-3p/FOXP1/Smad axis
Nature » Stem cells
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2w ago
Umbilical cord mesenchymal stem cell-derived exosomes inhibits fibrosis in human endometrial stromal cells via miR-140-3p/FOXP1/Smad axis ..read more
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