Science with a Twist
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It's almost impossible to overstate how many aspects of daily life are impacted by science. From technologies that help ensure the quality of the water we drink to medicines that deliver lifesaving treatments it's all thanks to science. Each month, join Ron O'Brien, a science enthusiast from Thermo Fisher Scientific, the world leader in serving science, as he talks to experts who..
Science with a Twist
1M ago
Gene Therapy's Potential to Transform Rare Disease Treatment
Dr. Peter Marks highlights the groundbreaking advancements in gene therapy, especially for rare diseases with high unmet medical needs. He discusses the FDA's role in fostering these innovations, underscoring the importance of understanding gene therapy's application and ensuring its safe delivery. Dr. Marks emphasizes the challenges in manufacturing gene therapies, noting that overcoming these hurdles is essential for treating large populations and common diseases. This insight reflects on the hope and complexity of gene therapy, ai ..read more
Science with a Twist
5M ago
Brazil's Proactive Measures Against HIV
Brazil has been at the forefront of combating HIV, implementing proactive measures that have made a significant difference. The country began providing no-cost access to CD4 and viral load testing and antiretroviral drugs as early as 1996. This early intervention and consistent approach led to a remarkable outcome: the number of HIV cases in Brazil was significantly lower than initially predicted. An article from the New England Journal of Medicine stated that initial estimates predicted Brazil would have 1.2 million people infected with HIV by the year ..read more
Science with a Twist
8M ago
The Power of Passion in STEM
Eleanor emphasizes the importance of pursuing what you love in STEM. She advises students to focus on their interests rather than trying to impress judges or make a big impact. Eleanor encourages students to be scrappy and innovative and to believe in their ability to navigate through challenges. She underscores that STEM is not just for prodigies and professionals and that anyone can make a difference.
Community Can Help Advance STEM
Eleanor and Maya discuss the importance of community and mentorship in STEM. They highlight the need to break through t ..read more
Science with a Twist
9M ago
The Power of Pharmacogenomics
Jeff explains how pharmacogenomics, the study of how genes affect a person's response to medications, can revolutionize healthcare. By understanding a patient's genetic makeup, healthcare providers can prescribe the right medication and dosage, reducing trial and error, improving treatment effectiveness, and minimizing side effects. This approach acknowledges that each person is unique and recognizes the complex interplay of genetics and non-genetic factors to determine health outcomes.
Real-World Impact of Pharmacogenomics
Jeff provides real-world examples ..read more
Science with a Twist
11M ago
⚡PFAS stands for Per- and Polyfluoroalkyl Substances. Simply put, PFAS are man-made compounds synthesized in a laboratory. ''They were first made in the 1940s. Teflon was one of the very first developments of PFAS. PFAS is a universe of chemicals useful for lots of different consumer and industrial applications over the last 60 to 70 years. These include things like firefighting foam, stain repellents on carpets and textiles, and also mist suppressants to protect workers in chromium plating activities.''
⚡We all have the right to clean water, hence the necessity for testing it for PFAS. Althou ..read more
Science with a Twist
1y ago
⚡ Cell therapy is a promising field. Cell therapies can potentially transform medicine and treat some of the most severe diseases, like cancer. Wendell says, "That's one of the innate challenges here — how do you make something that's very controlled and specific and yet also very potent enough to really overcome the disease. And that's where we really think that cell therapies can be very powerful because cells can read different signals and then process that information almost, like I said, a little computer and then make very intelligent decisions but ones that are also still very potent in ..read more
Science with a Twist
1y ago
⚡ What are the ramifications from a clinical research perspective if diversity is not appropriately represented in a clinical study populations? Even as diversity becomes increasingly important across different sectors, minorities continue to be left out of clinical trials and medical research studies. So, why is diversity so critical in clinical trials? Nik explains, "I think in terms of the ramifications if diversity is not appropriately represented — I think we, unfortunately, saw this clearly playing out during the pandemic when we were seeing a lot of the data emerging that many underrepr ..read more
Science with a Twist
1y ago
⚡ Decentralized clinical trials aim to reduce patient burden. Decentralized clinical trials can help make research more patient-centric. Tim explains the role of decentralization, "It's fair to say that that change management component is absolutely critical in terms of the decentralized adoption, and I think, when I look ahead in terms of decentralization, I see an amazing landscape for patients and the partnerships with EmVenio and also the kind of opportunities Thermo Fisher Scientific has in really driving forward unique and collaborative solutions for the better of the patient and really ..read more
Science with a Twist
1y ago
⚡ There's a diversity mismatch in the oncology workforce. One of the biggest challenges in the oncology space is a lack of diversity in the workforce. The population of the United States is very diverse, while the oncology field is not. Dr. Upal Basu Roy says, "We know that the United States is very diverse. As we speak, the population is very diverse, and we have about 12% African Americans in the population — about 18% who identify as Hispanic/Latinx — and 3% of the population who identify as American Indians and Alaska natives. But is that diversity reflected in the oncology workforce? Abso ..read more
Science with a Twist
1y ago
⚡The most critical part is to shorten the time between doing the test and getting the results. From there, doctors will be better positioned to provide the best care to the patient. ''There's always pressure from the patient, the family, and the physician to start therapy as soon as possible. [...] So getting that test earlier allows us to do the right thing for the patients, improve their outcomes, and frankly, reduce costs.
⚡Staying up to date with changes is the most noticeable obstacle to providing targeted therapy. We expect medicine and science to advance, resulting in better solutions i ..read more