Journal of Alzheimer's Disease Blog
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The Journal of Alzheimer's Disease (JAD) is an international multidisciplinary journal to facilitate progress in understanding the etiology, pathogenesis, epidemiology, genetics, behavior, treatment, and psychology of Alzheimer's disease. The journal publishes research reports, reviews, short communications, hypotheses, ethics reviews, book reviews, and letters-to-the-editor.
Journal of Alzheimer's Disease Blog
1M ago
Weaver DF (2023) Alzheimer's disease as an innate autoimmune disease (AD2): A new molecular paradigm. Alzheimers Dement 19, 1086-1098 ..read more
Journal of Alzheimer's Disease Blog
10M ago
On January 6, 2023, the FDA granted an accelerated approval for lecanemab (branded Leqembi by Eisai and Biogen) in the treatment of early Alzheimer’s dementia (AD) patients ..read more
Journal of Alzheimer's Disease Blog
1y ago
Journal of Alzheimer's Disease Blog
1y ago
Protecting Progress: Communicating and Using Dementia Risk Evidence A transformation in our understanding of dementia is happening through advances in biomarkers, genetics, and other data used as dementia risk evidence (DRE) promising a future for precision dementia care. Last comment on 30 November 2022 by ..read more
Journal of Alzheimer's Disease Blog
1y ago
The prion hypothesis was developed in the context of misleading premises, skewed interpretations of experimental data and observations, and omission of previous findings and knowledge ..read more
Journal of Alzheimer's Disease Blog
2y ago
Music has a profound impact upon the lives of individuals living with Alzheimer’s disease and related dementias ..read more
Journal of Alzheimer's Disease Blog
2y ago
The identification of Aβ peptides as the major components of amyloid plaque and the discovery in familial cases of Alzheimer’s diseases (AD) of multiple mutations in the genes implicated in their production led to the formalization of the Amyloid Hypothesis (AHyp) [1 ..read more
Journal of Alzheimer's Disease Blog
2y ago
Journal of Alzheimer's Disease Blog
2y ago
Sometimes social pressures come to a head, and a moment of crisis offers opportunity. With the disastrous FDA approval of aducanumab (or Aduhelm, as the drug is known in its commercial existence) in June, the figurative “boil” of the Alzheimer’s disease movement has done just that ..read more
Journal of Alzheimer's Disease Blog
2y ago
Amyloids are insoluble extracellular depositions of protein fibrils with a typical X-ray diffraction pattern. Amyloid fibrils are composed of polypeptide chains arranged in a twisted β-pleated sheet conformation ..read more