Navigating CAR-T Survivorship
ASTCT Talks
by ASTCT
5d ago
In this latest episode of ASTCT Talks, Cory M. Edgar, DMSc, PA-C, sits down with Sarah Fitzmaurice, APRN, where they delve into the evolving landscape of survivorship care, particularly in the realm of CAR T-cell therapy. They discuss the development of CAR T-specific protocols, emphasizing the importance of post-treatment monitoring and patient education. They also explore the challenges of defining survivorship, the multidisciplinary nature of care, and insights into late effects, deconditioning, cognitive changes, and psychological concerns beyond the first year. Tune into this episode of ..read more
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Beyond BCMA: Exploring Talquetamab in Myeloma Therapy
ASTCT Talks
by ASTCT
2w ago
In this latest episode of ASTCT Talks, Dr. Rahul Banerjee, MD, FACP, sits down with Dr. Amrita Krishnan, MD. They delve into the use of GPRC5D as a target in myeloma therapy, specifically focusing on Talquetamab. Dr. Krishnan shares insights from the MonumenTAL-1 trial, discussing the dosing schedules and response rates with GPRC5D-targeted therapy. They explore the unique toxicities associated with this treatment, such as cytokine release syndrome and skin and nail toxicities. The conversation also touches on the considerations for patients who have previously received BCMA-targeted therapie ..read more
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Behind the Scenes of CAR-T Therapy at University of California, Davis
ASTCT Talks
by ASTCT
1M ago
In this latest episode of ASTCT Talks, Misty Evans, DNP, APRN, CPNP-AC, sits down with Flora Stondell, FNP, to delve into the intricacies of University of California, Davis’ (UC Davis’) transplant and cellular therapy program, with a specific focus on CAR-T cell therapy. In this insightful conversation, they discuss topics such as patient access, the timeline from referral to CAR-T therapy initiation, overcoming insurance barriers, and the patient education process. Stondell shares valuable insights gained from her experience in the field, highlighting the crucial role of advanced practice pr ..read more
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Revitalizar, Prosperar y Sobrevivir: El Poder del Movimiento en la Recuperación de los Trasplantes
ASTCT Talks
by ASTCT
1M ago
En este último episodio de ASTCT Talks, el Mensaje del Presidente de octubre, el Dr. Andrés Gómez De León está acompañado por el Dr. Miguel Perales, Presidente de ASTCT y Jefe del Servicio de Trasplante de Médula Ósea en Adultos del Memorial Sloan Kettering Cancer Center y Profesor de Medicina en Facultad de Medicina Weill Cornell. Profundizan en el papel vital, pero a menudo pasado por alto, de la actividad física en los trasplantes de terapia celular y hematopoyética, discutiendo desafíos, enfoques proactivos como la "prehabitación", la brecha en la investigación y los efectos transformadore ..read more
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Revitalize, Thrive, and Survive: The Power of Movement in Transplant Recovery
ASTCT Talks
by ASTCT
1M ago
In this latest episode of ASTCT Talks, the October President's Message, Dr. Andrés Gómez De León is joined by Dr. Miguel Perales, President of ASTCT and Chief of the Adult Bone Marrow Transplantation Service at Memorial Sloan Kettering Cancer Center and Professor of Medicine at Weill Cornell Medical College. They delve into the vital but often overlooked role of physical activity in hematopoietic and cell therapy transplants, discussing challenges, proactive approaches like "pre-hab," the research gap, and the transformative effects of movement on recovery. Click here to listen to this episod ..read more
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A PTCy of Relief: GVHD Prophylaxis in Matched Unrelated Donors
ASTCT Talks
by ASTCT
1M ago
In this latest episode of ASTCT Talks, Dr. Rebecca Gonzalez sits down with Dr. Katie Gatwood and Dr. Timothy Porter to kick off National Pharmacy Month by discussing the clinical implications of post-transplant cyclophosphamide (PTCy) use outside of the haploidentical setting. They delve into their respective cancer centers' primary donor sources for match unrelated donors and the breakdown of conditioning intensity within their hematologic patients. They delve into the future of PTCy discussing the potential for earlier de-escalation of immunosuppressants to limit drug-related toxicities and ..read more
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Navigating Intersectionality in GVHD and Transplant Medicine
ASTCT Talks
by ASTCT
2M ago
In this latest episode of ASTCT Talks, we sit down with Associate Professor Nada Hamad, senior staff specialist in bone marrow transplant, and a clinical and laboratory hematologist at St. Vincent’s hospital in Sydney, to explore the impact of intersectionality on graft-versus-host disease (GVHD) in transplant recipients. She dives into how gender and race can compound biases in research, education, and clinical practice, affecting GVHD severity and outcomes. Further discussions center on the need for research into how age, socioeconomic status, and geographic region intersect with GVHD incide ..read more
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Advancing ALL Treatment and Insights on MRD Monitoring
ASTCT Talks
by ASTCT
2M ago
In this latest episode of ASTCT Talks, Christina Cho, MD, interviews Lori Muffly, MD, MS. During the conversation, Dr. Muffly emphasizes the need for more randomized data in ALL treatment and addresses the unique challenges of treating young adults, including fertility preservation. Dr. Muffly also emphasizes the significance of measurable residual disease (MRD) monitoring using the clonoSEQ® Assay, offering valuable insights into leukemia care. About Lori Muffly, MD, MS Lori Muffly, MD, MS, an Associate Professor of Medicine at Stanford University, specializes in adult acute leukemia research ..read more
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Monitoring After CAR-T Therapy for Multiple Myeloma: The APP Perspective
ASTCT Talks
by ASTCT
3M ago
In this latest episode of ASTCT Talks, Rahul Banerjee interviews Josh Epworth, a lead nurse practitioner in the plasma cell disorders clinic at the Fred Hutchinson Cancer Center. They delve into the topic of monitoring after CAR-T therapy for multiple myeloma. Mr. Epworth shares insights from his experience in the outpatient setting, discussing issues like hypogammaglobulinemia, immune cell functionality, and infections that may arise after CAR-T treatment. They also touch on monitoring for cytomegalovirus (CMV) and other respiratory viruses, as well as the importance of developing close relat ..read more
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Titans of Transplant: Dr. Rick Jones
ASTCT Talks
by ASTCT
5M ago
In this latest episode of ASTCT Talks, Dr. Tania Jain engages in a conversation with Dr. Richard Jones, the BMT director and co-director of the Hematologic Malignancies Programs at Johns Hopkins University. He shares his journey in the field of oncology and transplantation, reflecting on the life events and experiences that led him to this path. He delves into the groundbreaking development of post-transplant cyclophosphamide (PTCy) and its significant impact on transplant procedures. Gain insights into the behind-the-scenes efforts and the role PTCy has played in expanding donor options and i ..read more
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