
Online Biology Notes
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Hi, I'm Gaurab Karki. I am a dedicated microbiologist with excellent technical and analytical microbiological skills. My primary research interest is intersection between immunology and virology focusing on the design and preclinical evaluation of vaccines targeting emerging viral pathogens. I am also interested in the analysis and characterization of the outbreak strain, molecular..
Online Biology Notes
6M ago
Glomerulonephritis- causes, symptoms, diagnosis and treatments What is Glomerulonephritis? Definition: Glomerulonephritis (GN) is an inflammatory condition affecting the glomeruli, the tiny filtering units within the kidneys. [...]
The post Glomerulonephritis- causes, symptoms, diagnosis and treatments appeared first on Online Biology Notes ..read more
Online Biology Notes
9M ago
What is Diabetes mellitus?
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia resulting from impaired insulin secretion
Classification of Diabetes I. Type 1 Diabetes
Insulin- dependent diabetes mellitus
Juvenile- onset diabetes
Characteristics of Type I Diabetes
Hypoinsulinemia
10% of diabetes case
Patient require insulin
Age onset is childhood
Ketoacidosis
Etiology of Type I Diabetes
Autoimmune disease
Selective destruction of beta cells by T cells
Several circulating antibodies against beta cells
Cause of autoimmune attack
Both genetic and environmental f ..read more
Online Biology Notes
9M ago
Pheromones
Pheromones are chemical messengers secreted or discharged outside the body of the organism that activates a social response in members of the same species.
The term “Pheromone” (Phero-to carry and hormone-to stimulate) was coined by Peter Karlson and Martin Lüscher in 1959.
They are ectohormones in nature.
Both plants and animals can release pheromones
First sex pheromone was identified in 1959 from silk moth (Bombyx mori) termed as bombykol.
Plants use pheromones to attract bees and other pollinators to their flowers.
Some plant pheromones have alike chemistry to ..read more
Online Biology Notes
1y ago
Approaches of DNA Microarrays Introduction:
DNA Microarray is one of the molecular detection techniques which is a collection of microscopic characteristics (commonly DNA) affixed to a solid surface.
Also termed as DNA chip or biochip.
DNA spots can be probed with the target molecules to result either qualitative or quantitative data.
Microarrays can be characterized on the basis of the nature of the probe, the solid support used and the specific technique used for target detection and/or probe addressing
Approaches of DNA microarrays
Some of the approaches of microarrays are;
Printed micro ..read more
Online Biology Notes
1y ago
Extraction of plant materials by solvent extraction method What is extraction of plant?
•Extraction can be defined as the treatment of the plant (or animal tissues) with solvent, where the medicinally active constituents are dissolved and most of the inert particles remain undissolved.
• The process of extraction developed into a distinct area and contributes mainly to the progress of phytochemistry.
• Extraction processes includes maceration, steam or hydro-distillation, pressing, decoction, infusion, percolation and Soxhlet extraction.
• It is difficult to find a production process in the pe ..read more
Online Biology Notes
1y ago
Bronchitis What is Bronchitis?
Bronchitis is defined as persistent cough with sputum production for atleast 3 month in 2 consecutive years
There are three types of bronchitis:
simple chronic bronchitis: it Is a kind of bronchitis in which cough is present with no physiologic evidence of airflow obstruction.
chronic asthmatic bronchitis: it is kind of bronchitis in which hyper reactive airways is present with intermittent bronchospasm and wheezing
obstructive chronic bronchitis: it is a kind of bronchitis in which there is development of chronic airflow obstruction_ emphysema in a heavy smok ..read more
Online Biology Notes
1y ago
Isolation of antibiotic producing microorganisms and Determination of antimicrobial spectrum of isolates Principle:
Soil is the prime storage of the microorganisms producing antibiotics which are able to inhibit the growth of other microorganisms. Antibiotics have been implemented in one or other forms for centuries. The screening of wild isolates from the soil has yielded the broad majority of new antibiotics. Even if the purification of several hundred naturally produced antibiotics has been performed, only a few have been proved to be successful to be used in medical practice. Those which ..read more
Online Biology Notes
1y ago
Spore staining technique: principle, requirements and procedure Principle:
Members of the anaerobic genera Clostridium and Desulfotomaculum and the aerobic genus Bacillus are examples of organisms that have the capacity to exist either as metabolically active vegetative cells or as highly resistant, metabolically inactive cell types called spores. When environmental conditions become unfavorable for continuing vegetative cellular activities, particularly with the exhaustion of a nutritional carbon source, these cells have the capacity to undergo sporogenesis and give rise to a new intracellul ..read more
Online Biology Notes
1y ago
Puerperium: physiological changes in reproductive system and other systems of the body after child birth What is Puerperium?
Puerperium is a duration in which the reproductive organs and all the system of the body revert to their normal condition.
It is followed by the delivery of the placenta and ends approximately 6 weeks later.
Puerperium can also be defined as a period following childbirth in which the body tissues, particularly the pelvic organs return back approximately to the pre-pregnants state both anatomically and physiologically.
Puerperium or post partum period is term given for t ..read more
Online Biology Notes
2y ago
What is Biodiversity?
Biodiversity is defined as the variations among living organisms from all possible sources. It includes the variability within or between the species and within or between ecosystems.
According to the definition of the 1992 UN conference on Environment and Development (UNCED) Convention, biodiversity includes all of its manifestations. Therefore, along with terrestrial biodiversity, it also covers marine as well as other aquatic biodiversity. As such biodiversity means the richness and variety of living things in the world as a whole or in any location within it.
What a ..read more